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5DWQ
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BU of 5dwq by Molmil
Crystal structure of CARM1, sinefungin, and methylated H3 peptide (R17)
Descriptor: GLYCEROL, Histone-arginine methyltransferase CARM1, SINEFUNGIN, ...
Authors:Boriack-Sjodin, P.A.
Deposit date:2015-09-22
Release date:2015-11-25
Last modified:2025-04-02
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates.
Acs Chem.Biol., 11, 2016
4GUS
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BU of 4gus by Molmil
Crystal structure of LSD2-NPAC with H3 in space group P3221
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ...
Authors:Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GUR
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BU of 4gur by Molmil
Crystal structure of LSD2-NPAC with H3 in space group P21
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ...
Authors:Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y.
Deposit date:2012-08-29
Release date:2013-01-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4EO5
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BU of 4eo5 by Molmil
Yeast Asf1 bound to H3/H4G94P mutant
Descriptor: ACETATE ION, GLYCEROL, Histone H3.2, ...
Authors:Scorgie, J.K, Churchill, M.E.
Deposit date:2012-04-13
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The conformational flexibility of the C-terminus of histone H4 promotes histone octamer and nucleosome stability and yeast viability.
Epigenetics Chromatin, 5, 2012
3GL6
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BU of 3gl6 by Molmil
Crystal structure of JARID1A-PHD3 complexed with H3(1-9)K4me3 peptide
Descriptor: Histone H3, Histone demethylase JARID1A, ZINC ION
Authors:Wang, Z, Song, J, Patel, D.J.
Deposit date:2009-03-11
Release date:2009-05-05
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.
Nature, 459, 2009
3O34
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BU of 3o34 by Molmil
Crystal structure of TRIM24 PHD-Bromo complexed with H3(13-32)K23ac peptide
Descriptor: BIOTIN, Histone H3.1, Transcription intermediary factor 1-alpha, ...
Authors:Wang, Z, Patel, D.J.
Deposit date:2010-07-23
Release date:2010-12-15
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:TRIM24 links a non-canonical histone signature to breast cancer.
Nature, 468, 2010
3SOU
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BU of 3sou by Molmil
Structure of UHRF1 PHD finger in complex with histone H3 1-9 peptide
Descriptor: E3 ubiquitin-protein ligase UHRF1, Histone H3, ZINC ION
Authors:Rajakumara, E, Patel, D.J.
Deposit date:2011-06-30
Release date:2011-08-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8001 Å)
Cite:PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression.
Mol.Cell, 43, 2011
5Y2L
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BU of 5y2l by Molmil
Crystal structure of a group 2 HA binding antibody AF4H1K1 Fab in complex with the 1968 H3N2 pandemic (H3-AC/68) hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Xiao, H, Qi, J, Gao, F.G.
Deposit date:2017-07-26
Release date:2019-01-30
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.902 Å)
Cite:An H3-clade neutralizing antibody screened from an H7N9 patient that binds group 2 influenza A hemagglutinins
To Be Published
3UII
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BU of 3uii by Molmil
crystal structure of human Survivin in complex with H3(1-10) peptide
Descriptor: Baculoviral IAP repeat-containing protein 5, ZINC ION, histone H3(1-10) peptide
Authors:Du, J, Patel, D.J.
Deposit date:2011-11-04
Release date:2012-02-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin.
Structure, 20, 2012
8GE0
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BU of 8ge0 by Molmil
Crystal structure of JADE1 PZP domain in complex with Histone H3
Descriptor: Histone H3.1,Protein Jade-1, ZINC ION
Authors:Klein, B.J, Liu, J, Kutateladze, T.G.
Deposit date:2023-03-06
Release date:2024-03-13
Last modified:2024-07-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Guiding the HBO1 complex function through the JADE subunit.
Nat.Struct.Mol.Biol., 31, 2024
8I60
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BU of 8i60 by Molmil
Crystal structure of GAS41 YEATS domain in complex with histone H3K27cr
Descriptor: ALA-ARG-KCR-SER-ALA-PRO, GLYCEROL, SULFATE ION, ...
Authors:Konuma, T, Zhou, M.-M.
Deposit date:2023-01-26
Release date:2023-07-26
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin.
Mol.Cell, 83, 2023
1DLF
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BU of 1dlf by Molmil
HIGH RESOLUTION CRYSTAL STRUCTURE OF THE FV FRAGMENT FROM AN ANTI-DANSYL SWITCH VARIANT ANTIBODY IGG2A(S) CRYSTALLIZED AT PH 5.25
Descriptor: ANTI-DANSYL IMMUNOGLOBULIN IGG2A(S), SULFATE ION
Authors:Nakasako, M, Takahashi, H, Shimada, I, Arata, Y.
Deposit date:1998-07-14
Release date:1999-07-26
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The pH-dependent structural variation of complementarity-determining region H3 in the crystal structures of the Fv fragment from an anti-dansyl monoclonal antibody.
J.Mol.Biol., 291, 1999
2AJ3
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BU of 2aj3 by Molmil
Crystal Structure of a Cross-Reactive HIV-1 Neutralizing CD4-Binding Site Antibody Fab m18
Descriptor: Fab m18, Heavy Chain, Light Chain, ...
Authors:Prabakaran, P, Gan, J, Wu, Y.Q, Zhang, M.Y, Dimitrov, D.S, Ji, X.
Deposit date:2005-08-01
Release date:2006-03-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural mimicry of CD4 by a cross-reactive HIV-1 neutralizing antibody with CDR-H2 and H3 containing unique motifs.
J.Mol.Biol., 357, 2006
5BT1
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BU of 5bt1 by Molmil
histone chaperone Hif1 playing with histone H2A-H2B dimer
Descriptor: HAT1-interacting factor 1, Histone H2A.1, Histone H2B.1
Authors:Liu, H, Zhang, M, Gao, Y, Teng, M, Niu, L.
Deposit date:2015-06-02
Release date:2016-10-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structural Insights into the Association of Hif1 with Histones H2A-H2B Dimer and H3-H4 Tetramer
Structure, 24, 2016
2R0Y
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BU of 2r0y by Molmil
Structure of the Rsc4 tandem bromodomain in complex with an acetylated H3 peptide
Descriptor: Chromatin structure-remodeling complex protein RSC4, Histone H3 peptide
Authors:VanDemark, A.P, Kasten, M.M, Ferris, E, Heroux, A, Hill, C.P, Cairns, B.R.
Deposit date:2007-08-21
Release date:2007-10-30
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
Mol.Cell, 27, 2007
9BDG
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BU of 9bdg by Molmil
Influenza A virus Hemagglutinin H3/Darwin/6/2021 in complex with Fab ADI-85647
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab ADI-85647 Heavy chain, ...
Authors:Ferreira Ramos, A.S, Bajic, G.
Deposit date:2024-04-11
Release date:2024-11-13
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Influenza A virus Hemagglutinin H3/Darwin/6/2021 in complex with Fab ADI-85647
To Be Published
9BDF
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BU of 9bdf by Molmil
Influenza A virus Hemagglutinin H3/Darwin/6/2021 in complex with Fab ADI-85666
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-85666 Fab heavy chain, ...
Authors:Ferreira Ramos, A.S, Bajic, G.
Deposit date:2024-04-11
Release date:2024-11-13
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Influenza A virus Hemagglutinin H3/Darwin/6/2021 in complex with Fab ADI-85666
To be Published
4O62
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BU of 4o62 by Molmil
CW-type zinc finger of ZCWPW2 in complex with the amino terminus of histone H3
Descriptor: Histone H3.3, UNKNOWN ATOM OR ION, ZINC ION, ...
Authors:Liu, Y, Tempel, W, Dong, A, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2013-12-20
Release date:2014-03-26
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Family-wide Characterization of Histone Binding Abilities of Human CW Domain-containing Proteins.
J.Biol.Chem., 291, 2016
1TEY
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BU of 1tey by Molmil
NMR structure of human histone chaperone, ASF1A
Descriptor: ASF1 anti-silencing function 1 homolog A
Authors:Mousson, F, Lautrette, A, Thuret, J.Y, Agez, M, Amigues, B, Courbeyrette, R, Neumann, J.M, Guerois, R, Mann, C, Ochsenbein, F.
Deposit date:2004-05-26
Release date:2005-04-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural basis for the interaction of Asf1 with histone H3 and its functional implications.
Proc.Natl.Acad.Sci.Usa, 102, 2005
6OI2
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BU of 6oi2 by Molmil
Crystal structure of human WDR5 in complex with symmetric dimethyl-L-arginine
Descriptor: GLYCEROL, N3, N4-DIMETHYLARGININE, ...
Authors:Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D.
Deposit date:2019-04-08
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.
Biochemistry, 59, 2020
6OFZ
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BU of 6ofz by Molmil
Crystal structure of human WDR5
Descriptor: WD repeat-containing protein 5
Authors:Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D.
Deposit date:2019-04-01
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.
Biochemistry, 59, 2020
6OI1
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BU of 6oi1 by Molmil
Crystal structure of human WDR5 in complex with monomethyl L-arginine
Descriptor: (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, GLYCEROL, SULFATE ION, ...
Authors:Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D.
Deposit date:2019-04-08
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.
Biochemistry, 59, 2020
7VRF
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BU of 7vrf by Molmil
Crystal structure of Oxpecker chromodomain in complex with H3K9me3
Descriptor: H3K9me3, Oxpecker
Authors:Huang, Y, Jin, Z, Yu, B.
Deposit date:2021-10-22
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into the chromodomain of Oxpecker in complex with histone H3 lysine 9 trimethylation reveal a transposon silencing mechanism by heterodimerization.
Biochem.Biophys.Res.Commun., 652, 2023
2GF7
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BU of 2gf7 by Molmil
Double tudor domain structure
Descriptor: Jumonji domain-containing protein 2A, SULFATE ION
Authors:Huang, Y, Fang, J, Bedford, M.T, Zhang, Y, Xu, R.M.
Deposit date:2006-03-21
Release date:2006-05-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
Science, 312, 2006
5U7G
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BU of 5u7g by Molmil
Crystal Structure of the Catalytic Core of CBP
Descriptor: CREB-binding protein, ZINC ION
Authors:Park, S, Stanfield, R.L, Martinez-Yamout, M.M, Dyson, H.J, Wilson, I.A, Wright, P.E.
Deposit date:2016-12-12
Release date:2017-06-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

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