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8CU1
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BU of 8cu1 by Molmil
Structure of a K+ selective NaK mutant (NaK2K, Laue diffraction) in the presence of an electric field of ~0.8MV/cm along the crystallographic z axis, 500ns, with eightfold extrapolation of structure factor differences
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein, ...
Authors:Lee, B, White, K.I, Socolich, M.A, Klureza, M.A, Henning, R, Srajer, V, Ranganathan, R, Hekstra, D.
Deposit date:2022-05-16
Release date:2023-07-26
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Direct visualization of electric field-stimulated ion conduction in a potassium channel
To Be Published
8CU3
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BU of 8cu3 by Molmil
Structure of a K+ selective NaK mutant (NaK2K, Laue diffraction) in the presence of an electric field of ~0.8MV/cm along the crystallographic z axis, 200ns, with eightfold extrapolation of structure factor differences
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein, ...
Authors:Lee, B, White, K.I, Socolich, M.A, Klureza, M.A, Henning, R, Srajer, V, Ranganathan, R, Hekstra, D.
Deposit date:2022-05-16
Release date:2023-07-26
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Direct visualization of electric field-stimulated ion conduction in a potassium channel
To Be Published
8CU2
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BU of 8cu2 by Molmil
Structure of a K+ selective NaK mutant (NaK2K, Laue diffraction) in the presence of an electric field of ~0.8MV/cm along the crystallographic z axis, 100ns, with eightfold extrapolation of structure factor differences
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein, ...
Authors:Lee, B, White, K.I, Socolich, M.A, Klureza, M.A, Henning, R, Srajer, V, Ranganathan, R, Hekstra, D.
Deposit date:2022-05-16
Release date:2023-07-26
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Direct visualization of electric field-stimulated ion conduction in a potassium channel
To Be Published
6V22
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BU of 6v22 by Molmil
Cryo-EM structure of Ca2+-bound hsSlo1-beta4 channel complex
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Tao, X, MacKinnon, R.
Deposit date:2019-11-22
Release date:2019-12-25
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Molecular structures of the human Slo1 K + channel in complex with beta 4.
Elife, 8, 2019
1BUN
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BU of 1bun by Molmil
STRUCTURE OF BETA2-BUNGAROTOXIN: POTASSIUM CHANNEL BINDING BY KUNITZ MODULES AND TARGETED PHOSPHOLIPASE ACTION
Descriptor: BETA2-BUNGAROTOXIN, SODIUM ION
Authors:Kwong, P.D, Mcdonald, N.Q, Sigler, P.B, Hendrickson, W.A.
Deposit date:1995-10-15
Release date:1996-04-03
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of beta 2-bungarotoxin: potassium channel binding by Kunitz modules and targeted phospholipase action.
Structure, 3, 1995
7LJ5
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BU of 7lj5 by Molmil
Human TRAAK K+ channel FHIEG mutant A198E in a K+ bound conductive conformation
Descriptor: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
Authors:Rietmeijer, R.A, Brohawn, S.G.
Deposit date:2021-01-28
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Physical basis for distinct basal and mechanically gated activity of the human K + channel TRAAK.
Neuron, 109, 2021
7LJB
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BU of 7ljb by Molmil
Human TRAAK K+ channel mutant G158D in a K+ bound conductive conformation
Descriptor: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
Authors:Rietmeijer, R.A, Brohawn, S.G.
Deposit date:2021-01-28
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Physical basis for distinct basal and mechanically gated activity of the human K + channel TRAAK.
Neuron, 109, 2021
7LJ4
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BU of 7lj4 by Molmil
Human TRAAK K+ channel FHEIG mutant A270P in a K+ bound conductive conformation
Descriptor: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
Authors:Rietmeijer, R.A, Brohawn, S.G.
Deposit date:2021-01-28
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.782 Å)
Cite:Physical basis for distinct basal and mechanically gated activity of the human K + channel TRAAK.
Neuron, 109, 2021
2HEO
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BU of 2heo by Molmil
General Structure-Based Approach to the Design of Protein Ligands: Application to the Design of Kv1.2 Potassium Channel Blockers.
Descriptor: 5'-D(*TP*CP*GP*CP*GP*CP*G)-3', Z-DNA binding protein 1
Authors:Magis, C, Gasparini, S, Charbonnier, J.B, Stura, E, Le Du, M.H, Menez, A, Cuniasse, P.
Deposit date:2006-06-21
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure-based secondary structure-independent approach to design protein ligands: Application to the design of Kv1.2 potassium channel blockers.
J.Am.Chem.Soc., 128, 2006
2K1E
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BU of 2k1e by Molmil
NMR studies of a channel protein without membranes: structure and dynamics of water-solubilized KcsA
Descriptor: water soluble analogue of potassium channel, KcsA
Authors:Ma, D, Xu, Y, Tillman, T, Tang, P, Meirovitch, E, Eckenhoff, R, Carnini, A.
Deposit date:2008-02-29
Release date:2008-11-11
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR studies of a channel protein without membranes: structure and dynamics of water-solubilized KcsA.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1B4G
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BU of 1b4g by Molmil
CONTROL OF K+ CHANNEL GATING BY PROTEIN PHOSPHORYLATION: STRUCTURAL SWITCHES OF THE INACTIVATION GATE, NMR, 22 STRUCTURES
Descriptor: POTASSIUM CHANNEL
Authors:Antz, C, Bauer, T, Kalbacher, H, Frank, R, Covarrubias, M, Kalbitzer, H.R, Ruppersberg, J.P, Baukrowitz, T, Fakler, B.
Deposit date:1998-12-22
Release date:1999-04-27
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Control of K+ channel gating by protein phosphorylation: structural switches of the inactivation gate.
Nat.Struct.Biol., 6, 1999
1B4I
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BU of 1b4i by Molmil
Control of K+ Channel Gating by protein phosphorylation: structural switches of the inactivation gate, NMR, 22 structures
Descriptor: POTASSIUM CHANNEL
Authors:Antz, C, Bauer, T, Kalbacher, H, Frank, R, Covarrubias, M, Kalbitzer, H.R, Ruppersberg, J.P, Baukrowitz, T, Fakler, B.
Deposit date:1998-12-22
Release date:1999-04-27
Last modified:2022-03-23
Method:SOLUTION NMR
Cite:Control of K+ channel gating by protein phosphorylation: structural switches of the inactivation gate.
Nat.Struct.Biol., 6, 1999
5VA1
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BU of 5va1 by Molmil
Cryo-EM structure of the human ether-a-go-go related K+ channel
Descriptor: Potassium voltage-gated channel subfamily H member 2
Authors:Wang, W.W, MacKinnon, R.
Deposit date:2017-03-24
Release date:2017-05-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM Structure of the Open Human Ether-a-go-go-Related K(+) Channel hERG.
Cell, 169, 2017
7PQT
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BU of 7pqt by Molmil
Apo human Kv3.1 cryo-EM structure
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily C member 1
Authors:Botte, M, Huber, S, Bucher, D, Klint, J.K, Rodriguez, D, Tagmose, L, Chami, M, Cheng, R, Hennig, M, Abdul Rhaman, W.
Deposit date:2021-09-20
Release date:2022-08-17
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 channel reveal a novel binding site for positive modulators.
Pnas Nexus, 1, 2022
6WLV
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BU of 6wlv by Molmil
TASK2 in MSP1D1 lipid nanodisc at pH 6.5
Descriptor: POTASSIUM ION, Potassium channel TASK2
Authors:Li, B, Brohawn, S.G.
Deposit date:2020-04-20
Release date:2020-07-15
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structural basis for pH gating of the two-pore domain K + channel TASK2.
Nature, 586, 2020
6WM0
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BU of 6wm0 by Molmil
TASK2 in MSP1D1 lipid nanodisc at pH 8.5
Descriptor: POTASSIUM ION, Potassium channel TASK2
Authors:Li, B, Brohawn, S.G.
Deposit date:2020-04-20
Release date:2020-07-15
Last modified:2020-10-28
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:Structural basis for pH gating of the two-pore domain K + channel TASK2.
Nature, 586, 2020
7LGV
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BU of 7lgv by Molmil
NMR structure of Beta-KTx14.3
Descriptor: Neurotoxin beta-KTx 14.3
Authors:Carranza-Gonzalez, L.E, Titaux-Delgado, G.A, del Rio-Portilla, J.F.
Deposit date:2021-01-21
Release date:2022-02-09
Last modified:2023-08-23
Method:SOLUTION NMR
Cite:Beta-KTx14.3, a scorpion toxin, blocks the human potassium channel KCNQ1.
Biochim Biophys Acta Proteins Proteom, 1871, 2023
7UK5
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BU of 7uk5 by Molmil
Human Kv4.2-KChIP2 channel complex in an open state, transmembrane region
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily D member 2
Authors:Zhao, H, Dai, Y, Lee, C.H.
Deposit date:2022-03-31
Release date:2022-06-29
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Activation and closed-state inactivation mechanisms of the human voltage-gated K V 4 channel complexes.
Mol.Cell, 82, 2022
4LLO
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BU of 4llo by Molmil
Structure of the eag domain-CNBHD complex of the mouse EAG1 channel
Descriptor: Potassium voltage-gated channel subfamily H member 1
Authors:Haitin, Y, Carlson, A.E, Zagotta, W.N.
Deposit date:2013-07-09
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.995 Å)
Cite:The structural mechanism of KCNH-channel regulation by the eag domain.
Nature, 501, 2013
2OVC
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BU of 2ovc by Molmil
Crystal structure of a coiled-coil tetramerization domain from Kv7.4 channels
Descriptor: Potassium voltage-gated channel subfamily KQT member 4
Authors:Howard, R.J, Clark, K.A, Holton, J.M, Minor, D.L.
Deposit date:2007-02-13
Release date:2007-03-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural Insight into KCNQ (Kv7) Channel Assembly and Channelopathy.
Neuron, 53, 2007
7UKD
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BU of 7ukd by Molmil
Human Kv4.2-KChIP2 channel complex in an inactivated state, class 2, transmembrane region
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily D member 2
Authors:Zhao, H, Dai, Y, Lee, C.H.
Deposit date:2022-04-01
Release date:2022-06-29
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Activation and closed-state inactivation mechanisms of the human voltage-gated K V 4 channel complexes.
Mol.Cell, 82, 2022
7UKC
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BU of 7ukc by Molmil
Human Kv4.2-KChIP2 channel complex in an inactivated state, class 1, transmembrane region
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily D member 2
Authors:Zhao, H, Dai, Y, Lee, C.H.
Deposit date:2022-04-01
Release date:2022-06-29
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Activation and closed-state inactivation mechanisms of the human voltage-gated K V 4 channel complexes.
Mol.Cell, 82, 2022
7UKE
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BU of 7uke by Molmil
Human Kv4.2-KChIP2 channel complex in an intermediate state, transmembrane region
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily D member 2
Authors:Zhao, H, Dai, Y, Lee, C.H.
Deposit date:2022-04-01
Release date:2022-06-29
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Activation and closed-state inactivation mechanisms of the human voltage-gated K V 4 channel complexes.
Mol.Cell, 82, 2022
1WPD
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BU of 1wpd by Molmil
Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins
Descriptor: Potassium channel toxin alpha-KTx 6.2,Potassium channel toxin alpha-KTx 6.3
Authors:Regaya, I, Beeton, C, Ferrat, G, Andreotti, N, Chandy, G.K, Darbon, H, De Waard, M, Sabatier, J.M.
Deposit date:2004-09-01
Release date:2004-10-19
Last modified:2019-12-18
Method:SOLUTION NMR
Cite:Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins
J.Biol.Chem., 279, 2004
1F6G
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BU of 1f6g by Molmil
POTASSIUM CHANNEL (KCSA) FULL-LENGTH FOLD
Descriptor: VOLTAGE-GATED POTASSIUM CHANNEL
Authors:Cortes, D.M, Perozo, E.
Deposit date:2000-06-21
Release date:2001-02-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating.
J.Gen.Physiol., 117, 2001

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