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6GDG
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Cryo-EM structure of the adenosine A2A receptor bound to a miniGs heterotrimer
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Garcia-Nafria, J, Lee, Y.
Deposit date:2018-04-23
Release date:2018-05-16
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (4.11 Å)
Cite:Cryo-EM structure of the adenosine A2Areceptor coupled to an engineered heterotrimeric G protein.
Elife, 7, 2018
6GD1
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BU of 6gd1 by Molmil
Structure of HuR RRM3
Descriptor: SODIUM ION, Thioredoxin 1,ELAV-like protein 1
Authors:Pabis, M, Sattler, M.
Deposit date:2018-04-21
Release date:2018-10-31
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
6H7J
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BU of 6h7j by Molmil
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND AGONIST ISOPRENALINE AND NANOBODY Nb80
Descriptor: Beta-1 adrenergic receptor, Camelid antibody fragment Nb80, HEGA-10, ...
Authors:Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G.
Deposit date:2018-07-31
Release date:2018-10-17
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis for high-affinity agonist binding in GPCRs.
Science, 364, 2019
6H7L
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BU of 6h7l by Molmil
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST DOBUTAMINE AND NANOBODY Nb6B9
Descriptor: Beta-1 adrenergic receptor, Camelid antibody fragment Nb6B9, DOBUTAMINE, ...
Authors:Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G.
Deposit date:2018-07-31
Release date:2018-10-17
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis for high-affinity agonist binding in GPCRs.
Science, 364, 2019
6H7O
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BU of 6h7o by Molmil
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND WEAK PARTIAL AGONIST CYANOPINDOLOL AND NANOBODY Nb6B9
Descriptor: 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, Beta-1 adrenergic receptor, Camelid antibody fragment Nb6B9, ...
Authors:Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G.
Deposit date:2018-07-31
Release date:2018-10-17
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis for high-affinity agonist binding in GPCRs.
Science, 364, 2019
6H7N
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BU of 6h7n by Molmil
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST XAMOTEROL AND NANOBODY Nb6B9
Descriptor: Beta-1 adrenergic receptor, Camelid antibody fragment Nb6B9, HEGA-10, ...
Authors:Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G.
Deposit date:2018-07-31
Release date:2018-10-17
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular basis for high affinity agonist binding in GPCRs
Biorxiv, 2018
6H7M
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BU of 6h7m by Molmil
ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST SALBUTAMOL AND NANOBODY Nb6B9
Descriptor: Beta-1 adrenergic receptor, Camelid antibody fragment Nb6B9, HEGA-10, ...
Authors:Warne, T, Edwards, P.C, Dore, A.S, Leslie, A.G.W, Tate, C.G.
Deposit date:2018-07-31
Release date:2018-10-17
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Molecular basis for high-affinity agonist binding in GPCRs.
Science, 364, 2019
9BW4
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BU of 9bw4 by Molmil
TXNL1-bound proteasome
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Gao, J, Yip, M.C.J, Shao, S.
Deposit date:2024-05-20
Release date:2025-06-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the TXNL1-bound proteasome
To Be Published
9E8N
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BU of 9e8n by Molmil
Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt3 at top of spiral staircase
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Arkinson, C, Gee, C.L, Martin, A.
Deposit date:2024-11-05
Release date:2024-12-04
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1.
Biorxiv, 2024
9E8J
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BU of 9e8j by Molmil
Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt1 at top of spiral staircase
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Arkinson, C, Gee, C.L, Martin, A.
Deposit date:2024-11-05
Release date:2024-12-04
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1.
Biorxiv, 2024
9E8I
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BU of 9e8i by Molmil
Human proteasome in resting state conformation bound to TXNL1 in Forward conformation
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Arkinson, C, Gee, C.L, Martin, A.
Deposit date:2024-11-05
Release date:2024-12-04
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1.
Biorxiv, 2024
9E8G
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BU of 9e8g by Molmil
Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt5 at top of spiral staircase
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Arkinson, C, Gee, C.L, Martin, A.
Deposit date:2024-11-05
Release date:2024-12-04
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1.
Biorxiv, 2024
9E8H
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BU of 9e8h by Molmil
Human proteasome in resting state conformation bound to TXNL1 in backward conformation
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Arkinson, C, Gee, C.L, Martin, A.
Deposit date:2024-11-05
Release date:2024-12-04
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1.
Biorxiv, 2024
9E8L
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BU of 9e8l by Molmil
Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt4 at top of spiral staircase
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Arkinson, C, Gee, C.L, Martin, A.
Deposit date:2024-11-05
Release date:2024-12-04
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1.
Biorxiv, 2024
9E8K
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BU of 9e8k by Molmil
Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt6 at top of spiral staircase
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Arkinson, C, Gee, C.L, Martin, A.
Deposit date:2024-11-05
Release date:2024-12-04
Method:ELECTRON MICROSCOPY (4.08 Å)
Cite:Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1.
Biorxiv, 2024
9E8O
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BU of 9e8o by Molmil
Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt2 at top of spiral staircase and partially unfolded Eos
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ...
Authors:Arkinson, C, Gee, C.L, Martin, A.
Deposit date:2024-11-05
Release date:2024-12-04
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1.
Biorxiv, 2024
1F6M
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BU of 1f6m by Molmil
CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THIOREDOXIN REDUCTASE, THIOREDOXIN, AND THE NADP+ ANALOG, AADP+
Descriptor: 3-AMINOPYRIDINE-ADENINE DINUCLEOTIDE PHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, THIOREDOXIN 1, ...
Authors:Lennon, B.W, Williams Jr, C.H, Ludwig, M.L.
Deposit date:2000-06-22
Release date:2000-08-30
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Twists in catalysis: alternating conformations of Escherichia coli thioredoxin reductase.
Science, 289, 2000

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