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8T8K
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Structure of Domain of Unknown Function 507 (DUF507) in Space Group C222(1)
Descriptor: DUF507 family protein, HEXANE-1,6-DIOL
Authors:Tanner, J.J, McKay, C.E.
Deposit date:2023-06-22
Release date:2023-08-30
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structure of domain of unknown function 507 (DUF507) reveals a new protein fold.
Sci Rep, 13, 2023
8T8I
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Structure of VHH-Fab complex with engineered Elbow FNQIKG, Crystal Kappa and SER substitutions
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Fab heavy chain, ...
Authors:Filippova, E.V, Thompson, I, Kossiakoff, A.A.
Deposit date:2023-06-22
Release date:2023-11-29
Last modified:2024-01-03
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8T8G
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BU of 8t8g by Molmil
C208A Streptococcus pyogenes Sortase A (spySrtA) bound to LPALA peptide
Descriptor: LEU-PRO-ALA-LEU-ALA-GLY, Sortase
Authors:Kodama, H.M, Amacher, J.F.
Deposit date:2023-06-22
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A unique binding mode of P1' Leu-containing target sequences for Streptococcus pyogenes sortase A results in alternative cleavage.
Rsc Chem Biol, 5, 2024
8T8F
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Smc5/6 8mer
Descriptor: DNA repair protein KRE29, Non-structural maintenance of chromosome element 4, Non-structural maintenance of chromosome element 5, ...
Authors:Yu, Y, Patel, D.J.
Deposit date:2023-06-22
Release date:2023-11-15
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Molecular basis for Nse5-6 mediated regulation of Smc5/6 functions.
Proc.Natl.Acad.Sci.USA, 120, 2023
8T8E
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BU of 8t8e by Molmil
cryoEM structure of Smc5/6 5mer
Descriptor: DNA repair protein KRE29, Non-structural maintenance of chromosome element 5, Structural maintenance of chromosomes protein 6
Authors:Yu, Y, Patel, D.J.
Deposit date:2023-06-22
Release date:2023-11-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular basis for Nse5-6 mediated regulation of Smc5/6 functions.
Proc.Natl.Acad.Sci.USA, 120, 2023
8T8D
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BU of 8t8d by Molmil
Structure of Helicobacter pylori adhesin A, HpaA
Descriptor: ACETATE ION, GLYCEROL, Neuraminyllactose-binding hemagglutinin
Authors:Martini, C, Calmettes, C.
Deposit date:2023-06-22
Release date:2024-01-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Unraveling the crystal structure of the HpaA adhesin: insights into cell adhesion function and epitope localization of a Helicobacter pylori vaccine candidate.
Mbio, 15, 2024
8T8C
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BU of 8t8c by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site formyl-MFI-tripeptidyl-tRNA analog ACCA-IFMf at 2.60A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
Authors:Thaler, J, Syroegin, E.A, Breuker, K, Polikanov, Y.S, Micura, R.
Deposit date:2023-06-22
Release date:2023-07-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Practical Synthesis of N -Formylmethionylated Peptidyl-tRNA Mimics.
Acs Chem.Biol., 18, 2023
8T8B
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BU of 8t8b by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site formyl-MAI-tripeptidyl-tRNA analog ACCA-IAMf at 2.65A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
Authors:Thaler, J, Syroegin, E.A, Breuker, K, Polikanov, Y.S, Micura, R.
Deposit date:2023-06-22
Release date:2023-07-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Practical Synthesis of N -Formylmethionylated Peptidyl-tRNA Mimics.
Acs Chem.Biol., 18, 2023
8T8A
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BU of 8t8a by Molmil
Structure of arginine oxidase from Pseudomonas sp. TRU 7192
Descriptor: Amine oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Takahashi, K, Yamaguchi, H, Tatsumi, M, Sugiki, M.
Deposit date:2023-06-22
Release date:2024-06-26
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis of arginine oxidase from Pseudomonas sp. TRU 7192
To Be Published
8T89
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BU of 8t89 by Molmil
Racemic mixture of amyloid beta segment 16-KLVFFA-21 forms heterochiral rippled beta-sheet
Descriptor: Racemic mixture of amyloid beta segment 16-KLVFFA-21, trifluoroacetic acid
Authors:Sawaya, M.R, Raskatov, J.A, Hazari, A.
Deposit date:2023-06-22
Release date:2023-11-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Racemic Peptides from Amyloid beta and Amylin Form Rippled beta-Sheets Rather Than Pleated beta-Sheets.
J.Am.Chem.Soc., 145, 2023
8T88
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FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, Oxadiazolone JJ004 bound
Descriptor: Fluorophosphonate-binding serine hydrolase E, MAGNESIUM ION, methyl 2-formyl-2-[4-(undec-10-ynamido)phenyl]hydrazine-1-carboxylate
Authors:Fellner, M.
Deposit date:2023-06-22
Release date:2024-03-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections.
J.Am.Chem.Soc., 146, 2024
8T87
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BU of 8t87 by Molmil
FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, unbound dimer crystal form 1
Descriptor: Fluorophosphonate-binding serine hydrolase E, MAGNESIUM ION
Authors:Fellner, M.
Deposit date:2023-06-22
Release date:2024-03-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections.
J.Am.Chem.Soc., 146, 2024
8T86
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BU of 8t86 by Molmil
Racemic mixture of amylin segment 25-AILSS-29 forms heterochiral rippled beta-sheet
Descriptor: Racemic mixture of amylin segment 25-AILSS-29
Authors:Sawaya, M.R, Raskatov, J.A, Hazari, A, Sajimon, M.
Deposit date:2023-06-21
Release date:2023-11-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.102 Å)
Cite:Racemic Peptides from Amyloid beta and Amylin Form Rippled beta-Sheets Rather Than Pleated beta-Sheets.
J.Am.Chem.Soc., 145, 2023
8T85
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BU of 8t85 by Molmil
Structure of RssB bound to beryllofluoride
Descriptor: BERYLLIUM TRIFLUORIDE ION, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
Authors:Brugger, C, Schwartz, J, Deaconescu, A.M.
Deposit date:2023-06-21
Release date:2024-01-17
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure of phosphorylated-like RssB, the adaptor delivering sigma s to the ClpXP proteolytic machinery, reveals an interface switch for activation.
J.Biol.Chem., 299, 2023
8T84
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BU of 8t84 by Molmil
Racemic mixture of amyloid beta segment 35-MVGGVV-40 forms heterochiral rippled beta-sheet, includes hexafluoroisopropanol
Descriptor: 1,1,1,3,3,3-hexafluoropropan-2-ol, Racemic mixture of amyloid beta segment 35-MVGGVV-40
Authors:Sawaya, M.R, Raskatov, J.A, Hazari, A.
Deposit date:2023-06-21
Release date:2023-11-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.101 Å)
Cite:Racemic Peptides from Amyloid beta and Amylin Form Rippled beta-Sheets Rather Than Pleated beta-Sheets.
J.Am.Chem.Soc., 145, 2023
8T83
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BU of 8t83 by Molmil
X-ray crystal structure of PfA-M1(M462K)
Descriptor: Aminopeptidase N, GLYCEROL, ZINC ION
Authors:Yang, W, Drinkwater, N, Webb, C.T, McGowan, S.
Deposit date:2023-06-21
Release date:2024-06-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational dynamics of the Plasmodium falciparum M1 aminopeptidase.
To Be Published
8T82
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Racemic mixture of amyloid beta segment 35-MVGGVV-40 forms heterochiral rippled beta-sheet, includes pentafluoropropionic acid
Descriptor: amyloid beta segment 35-MVGGVV-40, racemic mixture, pentafluoropropanoic acid
Authors:Sawaya, M.R, Raskatov, J.A, Hazari, A.
Deposit date:2023-06-21
Release date:2023-11-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Racemic Peptides from Amyloid beta and Amylin Form Rippled beta-Sheets Rather Than Pleated beta-Sheets.
J.Am.Chem.Soc., 145, 2023
8T81
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BU of 8t81 by Molmil
Influenza PAN endonuclease E23K mutant with 6-(4-(1H-tetrazol-5-yl)-2-(trifluoromethyl)phenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid
Descriptor: (6M)-3-hydroxy-4-oxo-6-[(4M)-4-(1H-tetrazol-5-yl)-2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein
Authors:Kohlbrand, A.J, Cohen, S.M.
Deposit date:2023-06-21
Release date:2024-05-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Studies of Inhibitors with Clinically Relevant Influenza Endonuclease Variants.
Biochemistry, 63, 2024
8T80
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BU of 8t80 by Molmil
Sequence specific (AATT) orientation of Hoechst molecules at two unique minor groove binding sites within a self-assembled 3D DNA lattice (4x5)
Descriptor: 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*GP*AP*GP*AP*AP*TP*TP*CP*CP*TP*GP*AP*CP*GP*AP*CP*AP*AP*TP*TP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*TP*TP*GP*T)-3'), ...
Authors:Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H.
Deposit date:2023-06-21
Release date:2023-12-20
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Site-Specific Arrangement and Structure Determination of Minor Groove Binding Molecules in Self-Assembled Three-Dimensional DNA Crystals.
J.Am.Chem.Soc., 145, 2023
8T7Z
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BU of 8t7z by Molmil
Crystal structure of alpha-glucosidase (yicI) from Klebsiella aerogenes
Descriptor: Alpha-glucosidase yicI
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-06-21
Release date:2023-07-05
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of alpha-glucosidase (yicI) from Klebsiella aerogenes
To be published
8T7Y
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BU of 8t7y by Molmil
Structure of SARS CoV-2 main protease in complex with Chymostatin.
Descriptor: 3C-like proteinase nsp5, Chymostatin A (bound form)
Authors:Terzyan, S, Yarla, N, Rao, C.V, Mooers, B.
Deposit date:2023-06-21
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structure of SARS CoV-2 main protease in complex with Chymostatin.
to be published
8T7X
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BU of 8t7x by Molmil
Sequence specific (AATT) orientation of DAPI molecules at two unique minor groove binding sites within a self-assembled 3D DNA lattice (4x5)
Descriptor: 6-AMIDINE-2-(4-AMIDINO-PHENYL)INDOLE, CACODYLATE ION, DNA (5'-D(*GP*AP*GP*AP*AP*TP*TP*CP*CP*TP*GP*AP*CP*GP*AP*CP*AP*AP*TP*TP*A)-3'), ...
Authors:Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H.
Deposit date:2023-06-21
Release date:2023-12-20
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Site-Specific Arrangement and Structure Determination of Minor Groove Binding Molecules in Self-Assembled Three-Dimensional DNA Crystals.
J.Am.Chem.Soc., 145, 2023
8T7W
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Crystal structure of Oxygen-dependent coproporphyrinogen-III oxidase (hemF) from Klebsiella aerogenes
Descriptor: 1,2-ETHANEDIOL, Oxygen-dependent coproporphyrinogen-III oxidase
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2023-06-21
Release date:2023-06-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of Oxygen-dependent coproporphyrinogen-III oxidase (hemF) from Klebsiella aerogenes
To be published
8T7V
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Co-crystal structure of KRIT1 with a 1-hydroxy 2-naphthaldehyde derivative (6-(furan-2-yl)-2-hydroxy-1-naphthaldehyde)
Descriptor: (7M)-7-(furan-2-yl)-2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Bruystens, J.G.H.
Deposit date:2023-06-21
Release date:2023-12-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
Acs Pharmacol Transl Sci, 6, 2023
8T7U
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BU of 8t7u by Molmil
ADP-bound Bcs1 (unsymmetrized)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Mitochondrial chaperone BCS1
Authors:Zhan, J, Xia, D.
Deposit date:2023-06-21
Release date:2024-06-05
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024

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PDB entries from 2024-07-17

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