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8G02
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BU of 8g02 by Molmil
YES Complex - E. coli MraY, Protein E PhiX174, E. coli SlyD
Descriptor: Lysis protein E, Peptidyl-prolyl cis-trans isomerase, Phospho-N-acetylmuramoyl-pentapeptide-transferase
Authors:Orta, A.K, Clemons, W.M, Li, Y.E.
Deposit date:2023-01-31
Release date:2023-07-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The mechanism of the phage-encoded protein antibiotic from Phi X174.
Science, 381, 2023
8DTY
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BU of 8dty by Molmil
Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
Authors:Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
Deposit date:2022-07-26
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions
To Be Published
7VMO
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BU of 7vmo by Molmil
Structure of recombinant RyR2 (Ca2+ dataset, class 1, open state)
Descriptor: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
Authors:Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
Deposit date:2021-10-09
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
7VMM
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BU of 7vmm by Molmil
Structure of recombinant RyR2 (EGTA dataset, class 1, closed state)
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
Authors:Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
Deposit date:2021-10-09
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
7VMN
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BU of 7vmn by Molmil
Structure of recombinant RyR2 (EGTA dataset, class 2, closed state)
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
Authors:Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
Deposit date:2021-10-09
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
7VMP
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BU of 7vmp by Molmil
Structure of recombinant RyR2 (Ca2+ dataset, class 2, open state)
Descriptor: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
Authors:Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
Deposit date:2021-10-09
Release date:2022-08-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
8UXH
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BU of 8uxh by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the primed state in the presence of calcium
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-11-09
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8UXE
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BU of 8uxe by Molmil
Structure of PKA phosphorylated human RyR2-R420Q in the closed state in the presence of ARM210
Descriptor: 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-11-09
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
6WOT
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BU of 6wot by Molmil
Cryo-EM structure of recombinant rabbit Ryanodine Receptor type 1 mutant R164C in complex with FKBP12.6
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION
Authors:Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M.
Deposit date:2020-04-25
Release date:2020-08-05
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM.
Sci Adv, 6, 2020
8VK4
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BU of 8vk4 by Molmil
Structure of mouse RyR1 in complex with S100A1 (high-Ca2+/CFF/ATP dataset)
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ...
Authors:Weninger, G, Marks, A.R.
Deposit date:2024-01-08
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Structural insights into the regulation of RyR1 by S100A1.
To Be Published
8UXM
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BU of 8uxm by Molmil
Structure of PKA phosphorylated human RyR2-R420W in the open state in the presence of calcium and calmodulin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-11-09
Release date:2023-11-22
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8SEP
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BU of 8sep by Molmil
Cryo-EM Structure of RyR1 + ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glutathione S-transferase class-mu 26 kDa isozyme,Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
Authors:Cholak, S, Saville, J.W, Zhu, X, Berezuk, A.M, Tuttle, K.S, Haji-Ghassemi, O, Van Petegem, F, Subramaniam, S.
Deposit date:2023-04-10
Release date:2023-05-24
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives.
Structure, 31, 2023
7UA9
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BU of 7ua9 by Molmil
Structure of dephosphorylated human RyR2 in the open state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2022-03-11
Release date:2022-08-03
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
7WFF
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BU of 7wff by Molmil
Subcomplexes B,M and L in the Cylic electron transfer supercomplex NDH-PSI from Arabidopsis
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Pan, X.W, Li, M.
Deposit date:2021-12-26
Release date:2022-03-16
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:Supramolecular assembly of chloroplast NADH dehydrogenase-like complex with photosystem I from Arabidopsis thaliana.
Mol Plant, 15, 2022
6JI8
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BU of 6ji8 by Molmil
Structure of RyR2 (F/apoCaM dataset)
Descriptor: Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, RyR2, ...
Authors:Gong, D.S, Chi, X.M, Zhou, G.W, Huang, G.X.Y, Lei, J.L, Yan, N.
Deposit date:2019-02-20
Release date:2019-07-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Modulation of cardiac ryanodine receptor 2 by calmodulin.
Nature, 572, 2019
8DTZ
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BU of 8dtz by Molmil
Recombinant mouse RyR2 triple phosphonull mutant S2807A/S2813A/S2030A in complex with FKBP12.6 and nanodisc under closed-state conditions
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
Authors:Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
Deposit date:2022-07-26
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Recombinant mouse RyR2 triple phosphonull mutant S2807A/S2813A/S2030A in complex with FKBP12.6 and nanodisc under closed-state conditions
To Be Published
5T15
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BU of 5t15 by Molmil
Structural basis for gating and activation of RyR1 (30 uM Ca2+ dataset, all particles)
Descriptor: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1,Ryanodine receptor 1,Ryanodine receptor 1,Ryanodine receptor 1,Ryanodine receptor 1,Ryanodine receptor 1,Ryanodine receptor 1, ...
Authors:Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J.
Deposit date:2016-08-17
Release date:2016-10-12
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Basis for Gating and Activation of RyR1.
Cell, 167, 2016
8UQ4
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BU of 8uq4 by Molmil
Structure of human RyR2-S2808D in the subprimed state in the presence of H2O2/NOC-12/GSH
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2023-10-23
Release date:2023-11-15
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders
To Be Published
8JGA
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BU of 8jga by Molmil
Cryo-EM structure of Mi3 fused with FKBP
Descriptor: Peptidyl-prolyl cis-trans isomerase FKBP1A,2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase
Authors:Zhang, H.W, Kang, W, Xue, C.
Deposit date:2023-05-20
Release date:2024-04-24
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Dynamic Metabolons Using Stimuli-Responsive Protein Cages.
J.Am.Chem.Soc., 146, 2024
8DVV
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BU of 8dvv by Molmil
Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions
Descriptor: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
Authors:Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
Deposit date:2022-07-29
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions
To Be Published
7U9R
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BU of 7u9r by Molmil
Structure of PKA phosphorylated human RyR2 in the open state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
Authors:Miotto, M.C, Marks, A.R.
Deposit date:2022-03-11
Release date:2022-08-03
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment.
Sci Adv, 8, 2022
8JD1
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BU of 8jd1 by Molmil
Cryo-EM structure of mGlu2-mGlu3 heterodimer in Rco state
Descriptor: CHOLESTEROL, GLUTAMIC ACID, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ...
Authors:Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B.
Deposit date:2023-05-12
Release date:2023-06-21
Last modified:2023-10-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
6H3J
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BU of 6h3j by Molmil
Structural snapshots of the Type 9 protein translocon Plug-complex
Descriptor: Peptidyl-prolyl cis-trans isomerase, Plug, Protein involved in gliding motility SprA
Authors:Deme, J.C, Lea, S.M.
Deposit date:2018-07-18
Release date:2018-11-07
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Type 9 secretion system structures reveal a new protein transport mechanism.
Nature, 564, 2018
6JRS
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BU of 6jrs by Molmil
Structure of RyR2 (*F/A/C/L-Ca2+/Ca2+-CaM dataset)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
Authors:Gong, D.S, Chi, X.M, Zhou, G.W, Huang, G.X.Y, Lei, J.L, Yan, N.
Deposit date:2019-04-05
Release date:2019-07-17
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Modulation of cardiac ryanodine receptor 2 by calmodulin.
Nature, 572, 2019
8DUJ
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BU of 8duj by Molmil
Global map in C1 of RyR1 particles in complex with ImperaCalcin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
Authors:Haji-Ghassemi, O, Van Petegm, F.
Deposit date:2022-07-27
Release date:2023-05-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023

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PDB entries from 2024-06-12

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