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7PVK
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BU of 7pvk by Molmil
X-ray structure of dimeric PorX (T272A mutant), in complex with pGpG.
Descriptor: BERYLLIUM TRIFLUORIDE ION, FORMIC ACID, GLYCEROL, ...
Authors:Schmitz, C.A, Madej, M, Potempa, J, Sola, M.
Deposit date:2021-10-04
Release date:2022-12-14
Last modified:2023-01-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Response regulator PorX coordinates oligonucleotide signalling and gene expression to control the secretion of virulence factors
Nucleic Acids Res., 50, 2022
7LZA
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BU of 7lza by Molmil
Activated form of VanR from S. coelicolor
Descriptor: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Putative two-component system response regulator
Authors:Maciunas, L.J, Loll, P.J.
Deposit date:2021-03-09
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states.
Acta Crystallogr D Struct Biol, 77, 2021
7LZ9
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BU of 7lz9 by Molmil
Inactive form of VanR from S. coelicolor
Descriptor: MAGNESIUM ION, Putative two-component system response regulator
Authors:Maciunas, L.J, Loll, P.J.
Deposit date:2021-03-09
Release date:2021-07-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states.
Acta Crystallogr D Struct Biol, 77, 2021
5EP0
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BU of 5ep0 by Molmil
Quorum-Sensing Signal Integrator LuxO - Receiver+Catalytic Domains
Descriptor: 1,2-ETHANEDIOL, Putative repressor protein luxO, SULFATE ION
Authors:Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M.
Deposit date:2015-11-11
Release date:2016-04-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.
Plos Biol., 14, 2016
2WB4
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BU of 2wb4 by Molmil
activated diguanylate cyclase PleD in complex with c-di-GMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), BERYLLIUM TRIFLUORIDE ION, DIGUANYLATE CYCLASE, ...
Authors:Wassmann, P, Schirmer, T.
Deposit date:2009-02-20
Release date:2010-04-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Activated Pled, Identification of Dimerization and Catalysis Relevant Regulatory Mechanisms
To be Published
5DCL
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BU of 5dcl by Molmil
Structure of a lantibiotic response regulator: N terminal domain of the nisin resistance regulator NsrR
Descriptor: 1,2-ETHANEDIOL, PhoB family transcriptional regulator
Authors:Khosa, S, Kleinschrodt, D, Hoeppner, A, Smits, S.H.
Deposit date:2015-08-24
Release date:2016-03-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structure of the Response Regulator NsrR from Streptococcus agalactiae, Which Is Involved in Lantibiotic Resistance.
Plos One, 11, 2016
4CBV
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BU of 4cbv by Molmil
X-ray structure of full-length ComE from Streptococcus pneumoniae.
Descriptor: COME
Authors:Boudes, M, Durand, D, Graille, M, van Tilbeurgh, H, Quevillon-Cheruel, S.
Deposit date:2013-10-16
Release date:2014-02-12
Last modified:2014-05-14
Method:X-RAY DIFFRACTION (3.39 Å)
Cite:Structural Insights Into the Dimerization of the Response Regulator Come from Streptococcus Pneumoniae.
Nucleic Acids Res., 42, 2014
5DCM
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BU of 5dcm by Molmil
Structure of a lantibiotic response regulator: C-terminal domain of the nisin resistance regulator NsrR
Descriptor: PhoB family transcriptional regulator
Authors:Khosa, S, Kleinschrodt, D, Hoeppner, A, Smits, S.H.J.
Deposit date:2015-08-24
Release date:2016-07-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the Response Regulator NsrR from Streptococcus agalactiae, Which Is Involved in Lantibiotic Resistance.
Plos One, 11, 2016
4EUK
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BU of 4euk by Molmil
Crystal structure
Descriptor: 1,2-ETHANEDIOL, Histidine kinase 5, Histidine-containing phosphotransfer protein 1, ...
Authors:Stehle, T, Bauer, J.
Deposit date:2012-04-25
Release date:2013-02-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure-Function Analysis of Arabidopsis thaliana Histidine Kinase AHK5 Bound to Its Cognate Phosphotransfer Protein AHP1.
Mol Plant, 6, 2013
2V0N
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BU of 2v0n by Molmil
ACTIVATED RESPONSE REGULATOR PLED IN COMPLEX WITH C-DIGMP AND GTP- ALPHA-S
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, ...
Authors:Wassmann, P, Schirmer, T.
Deposit date:2007-05-15
Release date:2007-08-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structure of Bef3--Modified Response Regulator Pled: Implications for Diguanylate Cyclase Activation, Catalysis, and Feedback Inhibition
Structure, 15, 2007
4QIC
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BU of 4qic by Molmil
Co-Crystal Structure of Anti-anti-sigma factor PhyR complexed with Anti-sigma factor NepR from Bartonella quintana
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, Anti-sigma factor NepR, ...
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2014-05-30
Release date:2015-07-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Co-Crystal Structure of Anti-anti-sigma factor PhyR complexed with Anti-sigma factor NepR from Bartonella quintana
To be Published
4QPJ
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BU of 4qpj by Molmil
2.7 Angstrom Structure of a Phosphotransferase in Complex with a Receiver Domain
Descriptor: CALCIUM ION, CHLORIDE ION, Cell cycle response regulator CtrA, ...
Authors:Willett, J.W, Herrou, J, Crosson, S.
Deposit date:2014-06-23
Release date:2015-07-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.742 Å)
Cite:Structural asymmetry in a conserved signaling system that regulates division, replication, and virulence of an intracellular pathogen.
Proc.Natl.Acad.Sci.USA, 112, 2015
4S05
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BU of 4s05 by Molmil
Crystal structure of Klebsiella pneumoniae PmrA in complex with PmrA box DNA
Descriptor: BERYLLIUM TRIFLUORIDE ION, DNA (26-MER), DNA-binding transcriptional regulator BasR, ...
Authors:Hsiao, C.D, Weng, T.H, Li, Y.C.
Deposit date:2014-12-30
Release date:2015-11-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA.
Nat Commun, 6, 2015
4S04
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BU of 4s04 by Molmil
Crystal structure of Klebsiella pneumoniae PmrA in complex with PmrA box DNA
Descriptor: BERYLLIUM TRIFLUORIDE ION, DNA (25-MER), DNA-binding transcriptional regulator BasR, ...
Authors:Hsiao, C.D, Weng, T.H, Li, Y.C.
Deposit date:2014-12-30
Release date:2015-11-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA.
Nat Commun, 6, 2015
8OYP
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BU of 8oyp by Molmil
Crystal structure of Ubiquitin specific protease 11 (USP11) in complex with a substrate mimetic
Descriptor: CADMIUM ION, CHLORIDE ION, GLYCEROL, ...
Authors:Maurer, S.K, Caulton, S.G, Ward, S.J, Emsley, J, Dreveny, I.
Deposit date:2023-05-05
Release date:2023-10-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity.
J.Biol.Chem., 299, 2023
8P6F
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BU of 8p6f by Molmil
Crystal structure of PorX-Fj
Descriptor: ACETATE ION, MAGNESIUM ION, Response regulator receiver domain-containing protein, ...
Authors:Leone, P.
Deposit date:2023-05-26
Release date:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-function analysis of PorX Fj , the PorX homolog from Flavobacterium johnsioniae, suggests a role of the CheY-like domain in type IX secretion motor activity.
Sci Rep, 14, 2024
8PDC
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BU of 8pdc by Molmil
Complex of Histidine-containing phosphotransfer protein and receiver domain of hybrid Histidine Kinase 6 from Chaetomium thermophilum
Descriptor: BERYLLIUM TRIFLUORIDE ION, HPt domain-containing protein, MAGNESIUM ION, ...
Authors:Paredes-Martinez, F, Casino, P.
Deposit date:2023-06-12
Release date:2024-07-03
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional insights underlying recognition of histidine phosphotransfer protein in fungal phosphorelay systems.
Commun Biol, 7, 2024
8Q52
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BU of 8q52 by Molmil
A PBP-like protein built from fragments of different folds
Descriptor: Leucine-specific-binding protein,Chemotaxis protein CheY, SULFATE ION
Authors:Shanmugaratnam, S, Toledo-Patino, S, Goetz, S.K, Farias-Rico, J.A, Hocker, B.
Deposit date:2023-08-08
Release date:2024-04-10
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Molecular handcraft of a well-folded protein chimera.
Febs Lett., 598, 2024
5IUJ
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BU of 5iuj by Molmil
Crystal structure of the DesK-DesR complex in the phosphotransfer state with low Mg2+ (20 mM)
Descriptor: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ...
Authors:Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A.
Deposit date:2016-03-18
Release date:2016-12-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action.
Elife, 5, 2016
5IUL
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BU of 5iul by Molmil
Crystal structure of the DesK-DesR complex in the phosphotransfer state with high Mg2+ (150 mM) and BeF3
Descriptor: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ...
Authors:Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A.
Deposit date:2016-03-18
Release date:2016-12-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.153 Å)
Cite:Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action.
Elife, 5, 2016
5IUK
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BU of 5iuk by Molmil
Crystal structure of the DesK-DesR complex in the phosphotransfer state with high Mg2+ (150 mM)
Descriptor: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ...
Authors:Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A.
Deposit date:2016-03-18
Release date:2016-12-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action.
Elife, 5, 2016
5KBX
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BU of 5kbx by Molmil
Co-crystal structure of the Saccharomyces cerevisiae histidine phosphotransfer signaling protein Ypd1 and the receiver domain of its downstream response regulator Ssk1
Descriptor: GLYCEROL, Osmolarity two-component system protein SSK1, PHOSPHATE ION, ...
Authors:Menon, S.K, West, A.H.
Deposit date:2016-06-03
Release date:2017-06-07
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Insights revealed by the co-crystal structure of the Saccharomyces cerevisiae histidine phosphotransfer signaling protein Ypd1 and the receiver domain of its downstream response regulator Ssk1
To Be Published
6WW6
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BU of 6ww6 by Molmil
Crystal structure of EutV bound to RNA
Descriptor: BERYLLIUM TRIFLUORIDE ION, Response regulator, eutP P2
Authors:Ataide, S.F, Walshe, J.L.
Deposit date:2020-05-07
Release date:2021-11-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural characterization of the ANTAR antiterminator domain bound to RNA.
Nucleic Acids Res., 50, 2022
1SD5
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BU of 1sd5 by Molmil
Crystal structure of Rv1626
Descriptor: IODIDE ION, putative antiterminator
Authors:Morth, J.P, Feng, V, Perry, L.J, Svergun, D.I, Tucker, P.A, TB Structural Genomics Consortium (TBSGC)
Deposit date:2004-02-13
Release date:2004-09-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:The Crystal and Solution Structure of a Putative Transcriptional Antiterminator from Mycobacterium tuberculosis.
Structure, 12, 2004
1EAY
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BU of 1eay by Molmil
CHEY-BINDING (P2) DOMAIN OF CHEA IN COMPLEX WITH CHEY FROM ESCHERICHIA COLI
Descriptor: CHEA, CHEY
Authors:Mcevoy, M.M, Hausrath, A.C, Randolph, G.B, Remington, S.J, Dahlquist, F.W.
Deposit date:1998-04-23
Release date:1998-07-15
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Two binding modes reveal flexibility in kinase/response regulator interactions in the bacterial chemotaxis pathway.
Proc.Natl.Acad.Sci.USA, 95, 1998

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