7PVK
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![BU of 7pvk by Molmil](/molmil-images/mine/7pvk) | X-ray structure of dimeric PorX (T272A mutant), in complex with pGpG. | Descriptor: | BERYLLIUM TRIFLUORIDE ION, FORMIC ACID, GLYCEROL, ... | Authors: | Schmitz, C.A, Madej, M, Potempa, J, Sola, M. | Deposit date: | 2021-10-04 | Release date: | 2022-12-14 | Last modified: | 2023-01-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Response regulator PorX coordinates oligonucleotide signalling and gene expression to control the secretion of virulence factors Nucleic Acids Res., 50, 2022
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7LZA
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![BU of 7lza by Molmil](/molmil-images/mine/7lza) | Activated form of VanR from S. coelicolor | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Putative two-component system response regulator | Authors: | Maciunas, L.J, Loll, P.J. | Deposit date: | 2021-03-09 | Release date: | 2021-07-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states. Acta Crystallogr D Struct Biol, 77, 2021
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7LZ9
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![BU of 7lz9 by Molmil](/molmil-images/mine/7lz9) | Inactive form of VanR from S. coelicolor | Descriptor: | MAGNESIUM ION, Putative two-component system response regulator | Authors: | Maciunas, L.J, Loll, P.J. | Deposit date: | 2021-03-09 | Release date: | 2021-07-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states. Acta Crystallogr D Struct Biol, 77, 2021
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5EP0
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![BU of 5ep0 by Molmil](/molmil-images/mine/5ep0) | Quorum-Sensing Signal Integrator LuxO - Receiver+Catalytic Domains | Descriptor: | 1,2-ETHANEDIOL, Putative repressor protein luxO, SULFATE ION | Authors: | Shah, T, Selcuk, H.B, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2015-11-11 | Release date: | 2016-04-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO. Plos Biol., 14, 2016
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2WB4
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![BU of 2wb4 by Molmil](/molmil-images/mine/2wb4) | activated diguanylate cyclase PleD in complex with c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), BERYLLIUM TRIFLUORIDE ION, DIGUANYLATE CYCLASE, ... | Authors: | Wassmann, P, Schirmer, T. | Deposit date: | 2009-02-20 | Release date: | 2010-04-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Activated Pled, Identification of Dimerization and Catalysis Relevant Regulatory Mechanisms To be Published
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5DCL
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![BU of 5dcl by Molmil](/molmil-images/mine/5dcl) | Structure of a lantibiotic response regulator: N terminal domain of the nisin resistance regulator NsrR | Descriptor: | 1,2-ETHANEDIOL, PhoB family transcriptional regulator | Authors: | Khosa, S, Kleinschrodt, D, Hoeppner, A, Smits, S.H. | Deposit date: | 2015-08-24 | Release date: | 2016-03-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Structure of the Response Regulator NsrR from Streptococcus agalactiae, Which Is Involved in Lantibiotic Resistance. Plos One, 11, 2016
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4CBV
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![BU of 4cbv by Molmil](/molmil-images/mine/4cbv) | X-ray structure of full-length ComE from Streptococcus pneumoniae. | Descriptor: | COME | Authors: | Boudes, M, Durand, D, Graille, M, van Tilbeurgh, H, Quevillon-Cheruel, S. | Deposit date: | 2013-10-16 | Release date: | 2014-02-12 | Last modified: | 2014-05-14 | Method: | X-RAY DIFFRACTION (3.39 Å) | Cite: | Structural Insights Into the Dimerization of the Response Regulator Come from Streptococcus Pneumoniae. Nucleic Acids Res., 42, 2014
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5DCM
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![BU of 5dcm by Molmil](/molmil-images/mine/5dcm) | Structure of a lantibiotic response regulator: C-terminal domain of the nisin resistance regulator NsrR | Descriptor: | PhoB family transcriptional regulator | Authors: | Khosa, S, Kleinschrodt, D, Hoeppner, A, Smits, S.H.J. | Deposit date: | 2015-08-24 | Release date: | 2016-07-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the Response Regulator NsrR from Streptococcus agalactiae, Which Is Involved in Lantibiotic Resistance. Plos One, 11, 2016
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4EUK
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![BU of 4euk by Molmil](/molmil-images/mine/4euk) | Crystal structure | Descriptor: | 1,2-ETHANEDIOL, Histidine kinase 5, Histidine-containing phosphotransfer protein 1, ... | Authors: | Stehle, T, Bauer, J. | Deposit date: | 2012-04-25 | Release date: | 2013-02-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure-Function Analysis of Arabidopsis thaliana Histidine Kinase AHK5 Bound to Its Cognate Phosphotransfer Protein AHP1. Mol Plant, 6, 2013
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2V0N
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![BU of 2v0n by Molmil](/molmil-images/mine/2v0n) | ACTIVATED RESPONSE REGULATOR PLED IN COMPLEX WITH C-DIGMP AND GTP- ALPHA-S | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, ... | Authors: | Wassmann, P, Schirmer, T. | Deposit date: | 2007-05-15 | Release date: | 2007-08-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structure of Bef3--Modified Response Regulator Pled: Implications for Diguanylate Cyclase Activation, Catalysis, and Feedback Inhibition Structure, 15, 2007
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4QIC
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4QPJ
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![BU of 4qpj by Molmil](/molmil-images/mine/4qpj) | 2.7 Angstrom Structure of a Phosphotransferase in Complex with a Receiver Domain | Descriptor: | CALCIUM ION, CHLORIDE ION, Cell cycle response regulator CtrA, ... | Authors: | Willett, J.W, Herrou, J, Crosson, S. | Deposit date: | 2014-06-23 | Release date: | 2015-07-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.742 Å) | Cite: | Structural asymmetry in a conserved signaling system that regulates division, replication, and virulence of an intracellular pathogen. Proc.Natl.Acad.Sci.USA, 112, 2015
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4S05
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![BU of 4s05 by Molmil](/molmil-images/mine/4s05) | Crystal structure of Klebsiella pneumoniae PmrA in complex with PmrA box DNA | Descriptor: | BERYLLIUM TRIFLUORIDE ION, DNA (26-MER), DNA-binding transcriptional regulator BasR, ... | Authors: | Hsiao, C.D, Weng, T.H, Li, Y.C. | Deposit date: | 2014-12-30 | Release date: | 2015-11-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA. Nat Commun, 6, 2015
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4S04
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![BU of 4s04 by Molmil](/molmil-images/mine/4s04) | Crystal structure of Klebsiella pneumoniae PmrA in complex with PmrA box DNA | Descriptor: | BERYLLIUM TRIFLUORIDE ION, DNA (25-MER), DNA-binding transcriptional regulator BasR, ... | Authors: | Hsiao, C.D, Weng, T.H, Li, Y.C. | Deposit date: | 2014-12-30 | Release date: | 2015-11-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA. Nat Commun, 6, 2015
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8OYP
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![BU of 8oyp by Molmil](/molmil-images/mine/8oyp) | Crystal structure of Ubiquitin specific protease 11 (USP11) in complex with a substrate mimetic | Descriptor: | CADMIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Maurer, S.K, Caulton, S.G, Ward, S.J, Emsley, J, Dreveny, I. | Deposit date: | 2023-05-05 | Release date: | 2023-10-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity. J.Biol.Chem., 299, 2023
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8P6F
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![BU of 8p6f by Molmil](/molmil-images/mine/8p6f) | Crystal structure of PorX-Fj | Descriptor: | ACETATE ION, MAGNESIUM ION, Response regulator receiver domain-containing protein, ... | Authors: | Leone, P. | Deposit date: | 2023-05-26 | Release date: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-function analysis of PorX Fj , the PorX homolog from Flavobacterium johnsioniae, suggests a role of the CheY-like domain in type IX secretion motor activity. Sci Rep, 14, 2024
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8PDC
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8Q52
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![BU of 8q52 by Molmil](/molmil-images/mine/8q52) | A PBP-like protein built from fragments of different folds | Descriptor: | Leucine-specific-binding protein,Chemotaxis protein CheY, SULFATE ION | Authors: | Shanmugaratnam, S, Toledo-Patino, S, Goetz, S.K, Farias-Rico, J.A, Hocker, B. | Deposit date: | 2023-08-08 | Release date: | 2024-04-10 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Molecular handcraft of a well-folded protein chimera. Febs Lett., 598, 2024
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5IUJ
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![BU of 5iuj by Molmil](/molmil-images/mine/5iuj) | Crystal structure of the DesK-DesR complex in the phosphotransfer state with low Mg2+ (20 mM) | Descriptor: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... | Authors: | Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A. | Deposit date: | 2016-03-18 | Release date: | 2016-12-21 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action. Elife, 5, 2016
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5IUL
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![BU of 5iul by Molmil](/molmil-images/mine/5iul) | Crystal structure of the DesK-DesR complex in the phosphotransfer state with high Mg2+ (150 mM) and BeF3 | Descriptor: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... | Authors: | Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A. | Deposit date: | 2016-03-18 | Release date: | 2016-12-21 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.153 Å) | Cite: | Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action. Elife, 5, 2016
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5IUK
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![BU of 5iuk by Molmil](/molmil-images/mine/5iuk) | Crystal structure of the DesK-DesR complex in the phosphotransfer state with high Mg2+ (150 mM) | Descriptor: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... | Authors: | Trajtenberg, F, Imelio, J.A, Larrieux, N, Buschiazzo, A. | Deposit date: | 2016-03-18 | Release date: | 2016-12-21 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action. Elife, 5, 2016
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5KBX
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6WW6
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![BU of 6ww6 by Molmil](/molmil-images/mine/6ww6) | Crystal structure of EutV bound to RNA | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Response regulator, eutP P2 | Authors: | Ataide, S.F, Walshe, J.L. | Deposit date: | 2020-05-07 | Release date: | 2021-11-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural characterization of the ANTAR antiterminator domain bound to RNA. Nucleic Acids Res., 50, 2022
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1SD5
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![BU of 1sd5 by Molmil](/molmil-images/mine/1sd5) | Crystal structure of Rv1626 | Descriptor: | IODIDE ION, putative antiterminator | Authors: | Morth, J.P, Feng, V, Perry, L.J, Svergun, D.I, Tucker, P.A, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2004-02-13 | Release date: | 2004-09-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | The Crystal and Solution Structure of a Putative Transcriptional Antiterminator from Mycobacterium tuberculosis. Structure, 12, 2004
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1EAY
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![BU of 1eay by Molmil](/molmil-images/mine/1eay) | CHEY-BINDING (P2) DOMAIN OF CHEA IN COMPLEX WITH CHEY FROM ESCHERICHIA COLI | Descriptor: | CHEA, CHEY | Authors: | Mcevoy, M.M, Hausrath, A.C, Randolph, G.B, Remington, S.J, Dahlquist, F.W. | Deposit date: | 1998-04-23 | Release date: | 1998-07-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Two binding modes reveal flexibility in kinase/response regulator interactions in the bacterial chemotaxis pathway. Proc.Natl.Acad.Sci.USA, 95, 1998
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