5U8K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5u8k by Molmil](/molmil-images/mine/5u8k) | RitR mutant - C128S | Descriptor: | Response regulator | Authors: | Silvaggi, N.R, Han, L. | Deposit date: | 2016-12-14 | Release date: | 2017-12-20 | Last modified: | 2018-11-28 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization. PLoS Pathog., 14, 2018
|
|
5M7N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5m7n by Molmil](/molmil-images/mine/5m7n) | Crystal structure of NtrX from Brucella abortus in complex with ATP processed with the CrystalDirect automated mounting and cryo-cooling technology | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nitrogen assimilation regulatory protein | Authors: | Cornaciu, I, Fernandez, I, Hoffmann, G, Carrica, M.C, Goldbaum, F.A, Marquez, J.A. | Deposit date: | 2016-10-28 | Release date: | 2017-01-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Three-Dimensional Structure of Full-Length NtrX, an Unusual Member of the NtrC Family of Response Regulators. J. Mol. Biol., 429, 2017
|
|
5UXV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5uxv by Molmil](/molmil-images/mine/5uxv) | |
7VE6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ve6 by Molmil](/molmil-images/mine/7ve6) | N-terminal domain of VraR | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Response regulator protein VraR | Authors: | Kumar, J.V, Chen, C, Hsu, C.H. | Deposit date: | 2021-09-08 | Release date: | 2022-05-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Structural insights into DNA binding domain of vancomycin-resistance-associated response regulator in complex with its promoter DNA from Staphylococcus aureus. Protein Sci., 31, 2022
|
|
6LGQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lgq by Molmil](/molmil-images/mine/6lgq) | |
6AZR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6azr by Molmil](/molmil-images/mine/6azr) | Crystal structure of the T264A HK853cp-BeF3-RR468 complex | Descriptor: | Chemotaxis regulator-transmits chemoreceptor signals to flagelllar motor components CheY, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Rose, J, Zhou, P. | Deposit date: | 2017-09-11 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.628 Å) | Cite: | A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases. Nat Commun, 8, 2017
|
|
8AVX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8avx by Molmil](/molmil-images/mine/8avx) | |
8AVV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8avv by Molmil](/molmil-images/mine/8avv) | Cryo-EM structure of DrBphP photosensory module in Pr state | Descriptor: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome,Response regulator | Authors: | Wahlgren, W.Y, Takala, H, Westenhoff, S. | Deposit date: | 2022-08-27 | Release date: | 2022-12-21 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural mechanism of signal transduction in a phytochrome histidine kinase. Nat Commun, 13, 2022
|
|
7LZA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lza by Molmil](/molmil-images/mine/7lza) | Activated form of VanR from S. coelicolor | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Putative two-component system response regulator | Authors: | Maciunas, L.J, Loll, P.J. | Deposit date: | 2021-03-09 | Release date: | 2021-07-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states. Acta Crystallogr D Struct Biol, 77, 2021
|
|
7LZ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lz9 by Molmil](/molmil-images/mine/7lz9) | Inactive form of VanR from S. coelicolor | Descriptor: | MAGNESIUM ION, Putative two-component system response regulator | Authors: | Maciunas, L.J, Loll, P.J. | Deposit date: | 2021-03-09 | Release date: | 2021-07-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states. Acta Crystallogr D Struct Biol, 77, 2021
|
|
6WSH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wsh by Molmil](/molmil-images/mine/6wsh) | |
6WW6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ww6 by Molmil](/molmil-images/mine/6ww6) | Crystal structure of EutV bound to RNA | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Response regulator, eutP P2 | Authors: | Ataide, S.F, Walshe, J.L. | Deposit date: | 2020-05-07 | Release date: | 2021-11-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural characterization of the ANTAR antiterminator domain bound to RNA. Nucleic Acids Res., 50, 2022
|
|
8OYP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8oyp by Molmil](/molmil-images/mine/8oyp) | Crystal structure of Ubiquitin specific protease 11 (USP11) in complex with a substrate mimetic | Descriptor: | CADMIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Maurer, S.K, Caulton, S.G, Ward, S.J, Emsley, J, Dreveny, I. | Deposit date: | 2023-05-05 | Release date: | 2023-10-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity. J.Biol.Chem., 299, 2023
|
|
8P6F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p6f by Molmil](/molmil-images/mine/8p6f) | Crystal structure of PorX-Fj | Descriptor: | ACETATE ION, MAGNESIUM ION, Response regulator receiver domain-containing protein, ... | Authors: | Leone, P. | Deposit date: | 2023-05-26 | Release date: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure-function analysis of PorX Fj , the PorX homolog from Flavobacterium johnsioniae, suggests a role of the CheY-like domain in type IX secretion motor activity. Sci Rep, 14, 2024
|
|
8Q52
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8q52 by Molmil](/molmil-images/mine/8q52) | A PBP-like protein built from fragments of different folds | Descriptor: | Leucine-specific-binding protein,Chemotaxis protein CheY, SULFATE ION | Authors: | Shanmugaratnam, S, Toledo-Patino, S, Goetz, S.K, Farias-Rico, J.A, Hocker, B. | Deposit date: | 2023-08-08 | Release date: | 2024-04-10 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Molecular handcraft of a well-folded protein chimera. Febs Lett., 598, 2024
|
|
5M7P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5m7p by Molmil](/molmil-images/mine/5m7p) | Crystal structure of NtrX from Brucella abortus in complex with ADP processed with the CrystalDirect automated mounting and cryo-cooling technology | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nitrogen assimilation regulatory protein | Authors: | Cornaciu, I, Fernandez, I, Hoffmann, G, Carrica, M.C, Goldbaum, F.A, Marquez, J.A. | Deposit date: | 2016-10-28 | Release date: | 2017-01-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Three-Dimensional Structure of Full-Length NtrX, an Unusual Member of the NtrC Family of Response Regulators. J. Mol. Biol., 429, 2017
|
|
2WB4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wb4 by Molmil](/molmil-images/mine/2wb4) | activated diguanylate cyclase PleD in complex with c-di-GMP | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), BERYLLIUM TRIFLUORIDE ION, DIGUANYLATE CYCLASE, ... | Authors: | Wassmann, P, Schirmer, T. | Deposit date: | 2009-02-20 | Release date: | 2010-04-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of Activated Pled, Identification of Dimerization and Catalysis Relevant Regulatory Mechanisms To be Published
|
|
5O8Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5o8z by Molmil](/molmil-images/mine/5o8z) | Conformational dynamism for DNA interaction in Salmonella typhimurium RcsB response regulator. | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Transcriptional regulatory protein RcsB | Authors: | Casino, P, Marina, A, Miguel-Romero, L, Huesa, J. | Deposit date: | 2017-06-14 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Conformational dynamism for DNA interaction in the Salmonella RcsB response regulator. Nucleic Acids Res., 46, 2018
|
|
5O8Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5o8y by Molmil](/molmil-images/mine/5o8y) | Conformational dynamism for DNA interaction in Salmonella typhimurium RcsB response regulator. | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, SULFATE ION, Transcriptional regulatory protein RcsB | Authors: | Casino, P, Marina, A, Miguel-Romero, L, Huesa, J. | Deposit date: | 2017-06-14 | Release date: | 2017-11-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Conformational dynamism for DNA interaction in the Salmonella RcsB response regulator. Nucleic Acids Res., 46, 2018
|
|
4B09
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4b09 by Molmil](/molmil-images/mine/4b09) | Structure of unphosphorylated BaeR dimer | Descriptor: | HEXATANTALUM DODECABROMIDE, TRANSCRIPTIONAL REGULATORY PROTEIN BAER | Authors: | Choudhury, H, Beis, K. | Deposit date: | 2012-06-29 | Release date: | 2013-07-10 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The Dimeric Form of the Unphosphorylated Response Regulator Baer. Protein Sci., 22, 2013
|
|
7SSI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ssi by Molmil](/molmil-images/mine/7ssi) | |
7SSJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ssj by Molmil](/molmil-images/mine/7ssj) | |
3A0R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3a0r by Molmil](/molmil-images/mine/3a0r) | Crystal structure of histidine kinase ThkA (TM1359) in complex with response regulator protein TrrA (TM1360) | Descriptor: | MERCURY (II) ION, Response regulator, Sensor protein | Authors: | Yamada, S, Sugimoto, H, Kobayashi, M, Ohno, A, Nakamura, H, Shiro, Y. | Deposit date: | 2009-03-24 | Release date: | 2009-10-20 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structure of PAS-linked histidine kinase and the response regulator complex Structure, 17, 2009
|
|
4CBV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cbv by Molmil](/molmil-images/mine/4cbv) | X-ray structure of full-length ComE from Streptococcus pneumoniae. | Descriptor: | COME | Authors: | Boudes, M, Durand, D, Graille, M, van Tilbeurgh, H, Quevillon-Cheruel, S. | Deposit date: | 2013-10-16 | Release date: | 2014-02-12 | Last modified: | 2014-05-14 | Method: | X-RAY DIFFRACTION (3.39 Å) | Cite: | Structural Insights Into the Dimerization of the Response Regulator Come from Streptococcus Pneumoniae. Nucleic Acids Res., 42, 2014
|
|
4QIC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qic by Molmil](/molmil-images/mine/4qic) | |