3Q3X
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![BU of 3q3x by Molmil](/molmil-images/mine/3q3x) | Crystal structure of the main protease (3C) from human enterovirus B EV93 | Descriptor: | GLYCEROL, HEVB EV93 3C protease, MAGNESIUM ION | Authors: | Costenaro, L, Sola, M, Coutard, B, Norder, H, Canard, B, Coll, M. | Deposit date: | 2010-12-22 | Release date: | 2011-09-07 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93. J.Virol., 85, 2011
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4QUA
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![BU of 4qua by Molmil](/molmil-images/mine/4qua) | Caspase-3 Y195F | Descriptor: | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 | Authors: | Cade, C, Swartz, P.D, MacKenzie, S.H, Clark, A.C. | Deposit date: | 2014-07-10 | Release date: | 2014-11-05 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.892 Å) | Cite: | Modifying caspase-3 activity by altering allosteric networks. Biochemistry, 53, 2014
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3Q45
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![BU of 3q45 by Molmil](/molmil-images/mine/3q45) | Crystal structure of Dipeptide Epimerase from Cytophaga hutchinsonii complexed with Mg and dipeptide D-Ala-L-Val | Descriptor: | D-ALANINE, MAGNESIUM ION, Mandelate racemase/muconate lactonizing enzyme family; possible chloromuconate cycloisomerase, ... | Authors: | Lukk, T, Gerlt, J.A, Nair, S.K. | Deposit date: | 2010-12-22 | Release date: | 2011-02-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA, 109, 2012
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4QUB
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![BU of 4qub by Molmil](/molmil-images/mine/4qub) | Caspase-3 K137A | Descriptor: | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, AZIDE ION, Caspase-3 | Authors: | Cade, C, Swartz, P.D, MacKenzie, S.H, Clark, A.C. | Deposit date: | 2014-07-10 | Release date: | 2014-11-05 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.689 Å) | Cite: | Modifying caspase-3 activity by altering allosteric networks. Biochemistry, 53, 2014
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1MKW
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![BU of 1mkw by Molmil](/molmil-images/mine/1mkw) | |
3RUO
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![BU of 3ruo by Molmil](/molmil-images/mine/3ruo) | Complex structure of HevB EV93 main protease 3C with Rupintrivir (AG7088) | Descriptor: | 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, CHLORIDE ION, HEVB EV93 3C PROTEASE, ... | Authors: | Kaczmarska, Z, Janowski, R, Costenaro, L, Coutard, B, Norder, H, Canard, B, Coll, M. | Deposit date: | 2011-05-05 | Release date: | 2011-09-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93. J.Virol., 85, 2011
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3SHO
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3SJ9
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![BU of 3sj9 by Molmil](/molmil-images/mine/3sj9) | crystal structure of the C147A mutant 3C of CVA16 in complex with FAGLRQAVTQ peptide | Descriptor: | 3C protease, FAGLRQAVTQ peptide | Authors: | Lu, G, Qi, J, Chen, Z, Xu, X, Gao, F, Lin, D, Qian, W, Liu, H, Jiang, H, Yan, J, Gao, G.F. | Deposit date: | 2011-06-21 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.399 Å) | Cite: | Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design. J.Virol., 85, 2011
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1YT0
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![BU of 1yt0 by Molmil](/molmil-images/mine/1yt0) | Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL SOAKED WITH ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Endoplasmin, MAGNESIUM ION, ... | Authors: | Dollins, D.E, Immormino, R.M, Gewirth, D.T. | Deposit date: | 2005-02-09 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE J.Biol.Chem., 280, 2005
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3SJK
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![BU of 3sjk by Molmil](/molmil-images/mine/3sjk) | Crystal structure of the C147A mutant 3C from enterovirus 71 | Descriptor: | 3C protease, KPVLRTATVQGPSLDF peptide | Authors: | Lu, G, Qi, J, Chen, Z, Xu, X, Gao, F, Lin, D, Qian, W, Liu, H, Jiang, H, Yan, J, Gao, G.F. | Deposit date: | 2011-06-21 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.096 Å) | Cite: | Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design. J.Virol., 85, 2011
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1YT1
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![BU of 1yt1 by Molmil](/molmil-images/mine/1yt1) | Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL | Descriptor: | Endoplasmin, PENTAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL | Authors: | Dollins, D.E, Immormino, R.M, Gewirth, D.T. | Deposit date: | 2005-02-09 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE J.Biol.Chem., 280, 2005
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3R6V
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![BU of 3r6v by Molmil](/molmil-images/mine/3r6v) | Crystal structure of aspartase from Bacillus sp. YM55-1 with bound L-aspartate | Descriptor: | ASPARTIC ACID, Aspartase, CALCIUM ION | Authors: | Fibriansah, G, Puthan Veetil, V, Poelarends, G.J, Thunnissen, A.-M.W.H. | Deposit date: | 2011-03-22 | Release date: | 2011-07-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for the catalytic mechanism of aspartate ammonia lyase. Biochemistry, 50, 2011
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3R1Z
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![BU of 3r1z by Molmil](/molmil-images/mine/3r1z) | Crystal structure of NYSGRC enolase target 200555, a putative dipeptide epimerase from Francisella philomiragia : Complex with L-Ala-L-Glu and L-Ala-D-Glu | Descriptor: | ALANINE, D-GLUTAMIC ACID, Enzyme of enolase superfamily, ... | Authors: | Vetting, M.W, Hillerich, B, Seidel, R.D, Zencheck, W.D, Toro, R, Imker, H.J, Gerlt, J.A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2011-03-11 | Release date: | 2011-04-20 | Last modified: | 2012-03-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA, 109, 2012
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4PO4
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![BU of 4po4 by Molmil](/molmil-images/mine/4po4) | |
3RIT
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![BU of 3rit by Molmil](/molmil-images/mine/3rit) | Crystal structure of Dipeptide Epimerase from Methylococcus capsulatus complexed with Mg and dipeptide L-Arg-D-Lys | Descriptor: | ARGININE, D-LYSINE, Dipeptide epimerase, ... | Authors: | Lukk, T, Sakai, A, Song, L, Gerlt, J.A, Nair, S.K. | Deposit date: | 2011-04-14 | Release date: | 2011-04-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily. Proc.Natl.Acad.Sci.USA, 109, 2012
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4PMJ
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![BU of 4pmj by Molmil](/molmil-images/mine/4pmj) | Crystal structure of a putative oxidoreductase from Sinorhizobium meliloti 1021 in complex with NADP | Descriptor: | GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative oxidoreductase | Authors: | Gasiorowska, O.A, Shabalin, I.G, Handing, K.B, Szlachta, K, Zimmerman, M.D, Hillerich, B.S, Gizzi, A, Toro, R, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2014-05-21 | Release date: | 2014-06-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a putative oxidoreductase from Sinorhizobiummeliloti 1021 in complex with NADP to be published
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4PQH
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![BU of 4pqh by Molmil](/molmil-images/mine/4pqh) | Crystal structure of glutathione transferase lambda1 from Populus trichocarpa | Descriptor: | GLUTATHIONE, SODIUM ION, glutathione transferase lambda1 | Authors: | Lallement, P.A, Meux, E, Gualberto, J.M, Prosper, P, Didierjean, C, Haouz, A, Saul, F, Rouhier, N, Hecker, A. | Deposit date: | 2014-03-03 | Release date: | 2014-06-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural and enzymatic insights into Lambda glutathione transferases from Populus trichocarpa, monomeric enzymes constituting an early divergent class specific to terrestrial plants. Biochem.J., 462, 2014
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1Q3X
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![BU of 1q3x by Molmil](/molmil-images/mine/1q3x) | Crystal structure of the catalytic region of human MASP-2 | Descriptor: | GLYCEROL, Mannan-binding lectin serine protease 2, SODIUM ION | Authors: | Harmat, V, Gal, P, Kardos, J, Szilagyi, K, Ambrus, G, Naray-Szabo, G, Zavodszky, P. | Deposit date: | 2003-08-01 | Release date: | 2004-08-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions J.Mol.Biol., 342, 2004
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1PMC
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![BU of 1pmc by Molmil](/molmil-images/mine/1pmc) | |
3Q5T
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![BU of 3q5t by Molmil](/molmil-images/mine/3q5t) | |
4QTY
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![BU of 4qty by Molmil](/molmil-images/mine/4qty) | Caspase-3 E190A | Descriptor: | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, AZIDE ION, Caspase-3, ... | Authors: | Cade, C, Swartz, P.D, MacKenzie, S.H, Clark, A.C. | Deposit date: | 2014-07-09 | Release date: | 2014-11-05 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.602 Å) | Cite: | Modifying caspase-3 activity by altering allosteric networks. Biochemistry, 53, 2014
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4QU5
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![BU of 4qu5 by Molmil](/molmil-images/mine/4qu5) | Caspase-3 T140V | Descriptor: | ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, Caspase-3 | Authors: | Cade, C, Swartz, P.D, MacKenzie, S.H, Clark, A.C. | Deposit date: | 2014-07-10 | Release date: | 2014-11-05 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.908 Å) | Cite: | Modifying caspase-3 activity by altering allosteric networks. Biochemistry, 53, 2014
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4QUI
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![BU of 4qui by Molmil](/molmil-images/mine/4qui) | Caspase-3 F128AV266H | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACE-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE INHIBITOR, CHLORIDE ION, ... | Authors: | Cade, C, Swartz, P.D, MacKenzie, S.H, Clark, A.C. | Deposit date: | 2014-07-10 | Release date: | 2014-11-05 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.758 Å) | Cite: | Modifying caspase-3 activity by altering allosteric networks. Biochemistry, 53, 2014
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4Q1K
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![BU of 4q1k by Molmil](/molmil-images/mine/4q1k) | |
3RF0
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![BU of 3rf0 by Molmil](/molmil-images/mine/3rf0) | Crystal Structure of Exopolyphosphatase from Yersinia pestis | Descriptor: | Exopolyphosphatase, FORMIC ACID, NITRATE ION | Authors: | Kim, Y, Zhou, M, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-04-05 | Release date: | 2011-04-27 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Exopolyphosphatase from Yersinia pestis To be Published
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