8VI8
 
 | | Engineered glutamine binding protein and a cobaloxime ligand - no GLN bound | | Descriptor: | AZIDOBIS (DIMETHYLGLYOXIMATO) PYRIDINECOBALT, Amino acid ABC transporter substrate-binding protein, SODIUM ION, ... | | Authors: | Boggs, D.G, Fatima, S, Olshansky, L, Bridwell-Rabb, J. | | Deposit date: | 2024-01-03 | | Release date: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (3.21 Å) | | Cite: | Conformation-Dependent Hydrogen-Bonding Interactions in a Switchable Artificial Metalloprotein.
Biochemistry, 63, 2024
|
|
1LG6
 | | Crystal Structure Analysis of HCA II Mutant T199P in Complex with Thiocyanate | | Descriptor: | Carbonic anhydrase II, THIOCYANATE ION, ZINC ION | | Authors: | Huang, S, Sjoblom, B, Sauer-Eriksson, A.E, Jonsson, B.-H. | | Deposit date: | 2002-04-15 | | Release date: | 2002-07-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Organization of an efficient carbonic anhydrase: implications for the mechanism based on structure-function studies of a T199P/C206S mutant.
Biochemistry, 41, 2002
|
|
1OAZ
 | |
4KL7
 | | Crystal structure of the catalytic domain of RpfB from Mycobacterium tuberculosis | | Descriptor: | Resuscitation-promoting factor RpfB, SULFATE ION | | Authors: | Squeglia, F, Romano, M, Ruggiero, A, Berisio, R. | | Deposit date: | 2013-05-07 | | Release date: | 2013-06-26 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Carbohydrate Recognition by RpfB from Mycobacterium tuberculosis Unveiled by Crystallographic and Molecular Dynamics Analyses.
Biophys.J., 104, 2013
|
|
2MUL
 | | Solution Structure of the UBM1 domain of human HUWE1/ARF-BP1 | | Descriptor: | E3 ubiquitin-protein ligase HUWE1 | | Authors: | Farhadi, S, Khatun, R, Lemak, A, Kaustov, L, Ramabadran, R, Hunter, H, Sheng, Y. | | Deposit date: | 2014-09-12 | | Release date: | 2015-09-16 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure of Ubiquitin Binding Motif of human Arf-bp1
To be Published
|
|
1OAX
 | |
1PPI
 | | THE ACTIVE CENTER OF A MAMMALIAN ALPHA-AMYLASE. THE STRUCTURE OF THE COMPLEX OF A PANCREATIC ALPHA-AMYLASE WITH A CARBOHYDRATE INHIBITOR REFINED TO 2.2 ANGSTROMS RESOLUTION | | Descriptor: | 4,6-dideoxy-4-{[(1S,5R,6S)-3-formyl-5,6-dihydroxy-4-oxocyclohex-2-en-1-yl]amino}-alpha-D-xylo-hex-5-enopyranose-(1-4)-beta-D-glucopyranose, ALPHA-AMYLASE, CALCIUM ION, ... | | Authors: | Qian, M, Haser, R, Payan, F. | | Deposit date: | 1994-02-22 | | Release date: | 1995-05-24 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The active center of a mammalian alpha-amylase. Structure of the complex of a pancreatic alpha-amylase with a carbohydrate inhibitor refined to 2.2-A resolution.
Biochemistry, 33, 1994
|
|
2GAZ
 | | Mycobacterial lipoglycan presentation by CD1d | | Descriptor: | (2R)-3-[(HYDROXY{[(2R,3R,5S,6R)-3,4,5-TRIHYDROXY-2,6-BIS(ALPHA-D-MANNOPYRANOSYLOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]PROPAN E-1,2-DIYL DIHEXADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, T-cell surface glycoprotein CD1d1, ... | | Authors: | Zajonc, D.M. | | Deposit date: | 2006-03-09 | | Release date: | 2006-09-26 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Structural characterization of mycobacterial phosphatidylinositol mannoside binding to mouse CD1d.
J.Immunol., 177, 2006
|
|
6BRY
 | | Tubulin-RB3_SLD-TTL in complex with heterocyclic pyrimidine compound 6a | | Descriptor: | 1-(2-chlorofuro[3,2-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | Authors: | Kumar, G, Wang, Y, Li, W, White, S.W. | | Deposit date: | 2017-12-01 | | Release date: | 2018-06-27 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy.
J. Med. Chem., 61, 2018
|
|
1OAR
 | | Fv IgE SPE-7 in complex with Alizarin Red | | Descriptor: | 1,2-ETHANEDIOL, ALIZARIN RED, CACODYLATE ION, ... | | Authors: | James, L.C, Roversi, P, Tawfik, D. | | Deposit date: | 2003-01-21 | | Release date: | 2004-01-15 | | Last modified: | 2013-10-30 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Antibody Multispecificity Mediated by Conformational Diversity
Science, 299, 2003
|
|
1C5C
 | | DECARBOXYLASE CATALYTIC ANTIBODY 21D8-HAPTEN COMPLEX | | Descriptor: | 2-ACETYLAMINO-NAPTHALENE-1,5-DISULFONIC ACID, CHIMERIC DECARBOXYLASE ANTIBODY 21D8, GLYCEROL | | Authors: | Hotta, K, Wilson, I.A. | | Deposit date: | 1999-11-09 | | Release date: | 2000-10-11 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.61 Å) | | Cite: | Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: crystal structures of abzyme 21D8.
J.Mol.Biol., 302, 2000
|
|
2ZK7
 | | Structure of a C-terminal deletion mutant of Thermoplasma acidophilum aldohexose dehydrogenase (AldT) | | Descriptor: | Glucose 1-dehydrogenase related protein | | Authors: | Nishioka, T, Yasutake, Y, Nishiya, Y, Tamura, N, Tamura, T. | | Deposit date: | 2008-03-12 | | Release date: | 2009-01-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | C-terminal tail derived from the neighboring subunit is critical for the activity of Thermoplasma acidophilum D-aldohexose dehydrogenase
Proteins, 74, 2009
|
|
6W69
 | | The structure of F64, S172A Keap1-BTB domain | | Descriptor: | Kelch-like ECH-associated protein 1 | | Authors: | Mena, E.L, Gee, C.L, Kuriyan, J, Rape, M. | | Deposit date: | 2020-03-16 | | Release date: | 2020-08-19 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | Structural basis for dimerization quality control.
Nature, 586, 2020
|
|
5Z4P
 | | Crystal structure of tubulin-stathmin-TTL-Compound TCA complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6,7,8-trimethoxy-1-(4-methoxyphenyl)-4,5-dihydro-2~{H}-benzo[e]indazole, CALCIUM ION, ... | | Authors: | Zhang, H, Luo, C. | | Deposit date: | 2018-01-12 | | Release date: | 2019-01-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Discovery and Design of novel Tubulin inhibitors
To Be Published
|
|
2QM4
 | | Crystal structure of human XLF/Cernunnos, a non-homologous end-joining factor | | Descriptor: | Non-homologous end-joining factor 1 | | Authors: | Li, Y, Chirgadze, D.Y, Sibanda, B.L, Bolanos-Garcia, V.M, Davies, O.R, Blundell, T.L. | | Deposit date: | 2007-07-14 | | Release date: | 2007-12-11 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ.
Embo J., 27, 2008
|
|
1RGN
 | | Structure of the reaction centre from Rhodobacter sphaeroides carotenoidless strain R-26.1 reconstituted with spheroidene | | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (III) ION, ... | | Authors: | Roszak, A.W, Frank, H.A, McKendrick, K, Mitchell, I.A, Cogdell, R.J, Isaacs, N.W. | | Deposit date: | 2003-11-12 | | Release date: | 2004-04-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Protein Regulation of Carotenoid Binding: Gatekeeper and Locking Amino Acid Residues in Reaction Centers of Rhodobacter sphaeroides
STRUCTURE, 12, 2004
|
|
1RG5
 | | Structure of the photosynthetic reaction centre from Rhodobacter sphaeroides carotenoidless strain R-26.1 | | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... | | Authors: | Roszak, A.W, Hashimoto, H, Gardiner, A.T, Cogdell, R.J, Isaacs, N.W. | | Deposit date: | 2003-11-11 | | Release date: | 2004-04-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Protein Regulation of Carotenoid Binding: Gatekeeper and Locking Amino Acid Residues in Reaction Centers of Rhodobacter sphaeroides
STRUCTURE, 12, 2004
|
|
4GA2
 | |
6W68
 | |
1NEL
 | | FLUORIDE INHIBITION OF YEAST ENOLASE: CRYSTAL STRUCTURE OF THE ENOLASE-MG2+-F--PI COMPLEX AT 2.6-ANGSTROMS RESOLUTION | | Descriptor: | ENOLASE, FLUORIDE ION, MAGNESIUM ION, ... | | Authors: | Lebioda, L, Zhang, E, Lewinski, K, Brewer, M.J. | | Deposit date: | 1993-08-20 | | Release date: | 1994-01-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Fluoride inhibition of yeast enolase: crystal structure of the enolase-Mg(2+)-F(-)-Pi complex at 2.6 A resolution.
Proteins, 16, 1993
|
|
6J1C
 | | Photoswitchable fluorescent protein Gamillus, N150C/T204V double mutant, off-state | | Descriptor: | CHLORIDE ION, GLYCEROL, Green fluorescent protein | | Authors: | Nakashima, R, Shinoda, H, Matsuda, T, Nagai, T. | | Deposit date: | 2018-12-28 | | Release date: | 2019-11-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Acid-Tolerant Reversibly Switchable Green Fluorescent Protein for Super-resolution Imaging under Acidic Conditions.
Cell Chem Biol, 26, 2019
|
|
6W67
 | |
8OWZ
 | | Crystal structure of human Sirt2 in complex with a triazole-based SirReal | | Descriptor: | (R,R)-2,3-BUTANEDIOL, 1,2-ETHANEDIOL, 2-(4,6-dimethylpyrimidin-2-yl)sulfanyl-N-[5-[[3-[[1-(2-methoxyethyl)-1,2,3-triazol-4-yl]methoxy]phenyl]methyl]-1,3-thiazol-2-yl]ethanamide, ... | | Authors: | Friedrich, F, Zhang, L, Schiedel, M, Einsle, O, Jung, M. | | Deposit date: | 2023-04-28 | | Release date: | 2023-11-15 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation.
J.Med.Chem., 66, 2023
|
|
1NIG
 | |
2JTT
 | |
