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2RRB
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Refinement of RNA binding domain in human Tra2 beta protein
Descriptor: cDNA FLJ40872 fis, clone TUTER2000283, highly similar to Homo sapiens transformer-2-beta (SFRS10) gene
Authors:Tsuda, K, Kuwasako, K, Takahashi, M, Someya, T, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Sugano, S, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2010-06-17
Release date:2011-04-27
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for the dual RNA-recognition modes of human Tra2-beta RRM.
Nucleic Acids Res., 39, 2011
2SXL
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SEX-LETHAL RBD1, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: SEX-LETHAL PROTEIN
Authors:Inoue, M, Muto, Y, Sakamoto, H, Kigawa, T, Takio, K, Shimura, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1997-07-16
Release date:1998-07-22
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A characteristic arrangement of aromatic amino acid residues in the solution structure of the amino-terminal RNA-binding domain of Drosophila sex-lethal.
J.Mol.Biol., 272, 1997
2X1A
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Structure of Rna15 RRM with RNA bound (G)
Descriptor: 5'-R(*GP*UP*UP*GP*UP)-3', MAGNESIUM ION, MRNA 3'-END-PROCESSING PROTEIN RNA15
Authors:Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A.
Deposit date:2010-01-06
Release date:2010-02-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
2X1F
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Structure of Rna15 RRM with bound RNA (GU)
Descriptor: 5'-R(*GP*UP*UP*GP*UP)-3', MRNA 3'-END-PROCESSING PROTEIN RNA15
Authors:Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A.
Deposit date:2010-01-06
Release date:2010-02-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
2X1B
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Structure of RNA15 RRM
Descriptor: MRNA 3'-END-PROCESSING PROTEIN RNA15, PHOSPHATE ION
Authors:Pancevac, C, Goldstone, D.C, Ramos, A, Taylor, I.A.
Deposit date:2010-01-06
Release date:2010-02-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the RNA15 Rrm-RNA Complex Reveals the Molecular Basis of Gu Specificity in Transcriptional 3-End Processing Factors.
Nucleic Acids Res., 38, 2010
2RU3
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Solution structure of c.elegans SUP-12 RRM in complex with RNA
Descriptor: Protein SUP-12, isoform a, RNA (5'-R(*GP*UP*GP*UP*GP*C)-3')
Authors:Takahashi, M, Kuwasako, K, Unzai, S, Tsuda, K, Yoshikawa, S, He, F, Kobayashi, N, Guntert, P, Shirouzu, M, Ito, T, Tanaka, A, Yokoyama, S, Hagiwara, M, Kuroyanagi, H, Muto, Y.
Deposit date:2013-11-12
Release date:2014-08-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:RBFOX and SUP-12 sandwich a G base to cooperatively regulate tissue-specific splicing
Nat.Struct.Mol.Biol., 21, 2014
2XNR
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Structural insights into cis element recognition of non- polyadenylated RNAs by the Nab3-RRM
Descriptor: 5'-R(*UP*UP*CP*UP*UP*AP*UP*UP*CP*UP*UP*A)-3', ACETATE ION, NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3
Authors:Lunde, B.M, Horner, M, Meinhart, A.
Deposit date:2010-08-05
Release date:2010-09-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Insights Into Cis Element Recognition of Non-Polyadenylated Rnas by the Nab3-Rrm.
Nucleic Acids Res., 39, 2011
2XNQ
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Structural insights into cis element recognition of non- polyadenylated RNAs by the Nab3-RRM
Descriptor: ACETATE ION, NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3
Authors:Lunde, B.M, Horner, M, Meinhart, A.
Deposit date:2010-08-05
Release date:2010-09-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural Insights Into Cis Element Recognition of Non-Polyadenylated Rnas by the Nab3-Rrm.
Nucleic Acids Res., 39, 2011
2XS5
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Crystal structure of the RRM domain of mouse Deleted in azoospermia- like in complex with Mvh RNA, UGUUC
Descriptor: 5'-R(*UP*GP*UP*UP*CP)-3', DELETED IN AZOOSPERMIA-LIKE, DI(HYDROXYETHYL)ETHER
Authors:Jenkins, H.T, Edwards, T.A.
Deposit date:2010-09-24
Release date:2011-10-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Kinked Beta-Strands Mediate High-Affinity Recognition of Mrna Targets by the Germ-Cell Regulator Dazl
Proc.Natl.Acad.Sci.USA, 108, 2011
2XS7
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Crystal structure of the RRM domain of mouse Deleted in azoospermia- like in complex with Sycp3 RNA, UUGUUU
Descriptor: 5'-R(*UP*UP*GP*UP*UP*UP)-3', DELETED IN AZOOSPERMIA-LIKE, ZINC ION
Authors:Jenkins, H.T, Edwards, T.A.
Deposit date:2010-09-24
Release date:2011-10-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Kinked Beta-Strands Mediate High-Affinity Recognition of Mrna Targets by the Germ-Cell Regulator Dazl
Proc.Natl.Acad.Sci.USA, 108, 2011
2XSF
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Crystal structure of the RRM domain of mouse Deleted in azoospermia- like
Descriptor: DELETED IN AZOOSPERMIA-LIKE, GLYCEROL, SULFATE ION
Authors:Jenkins, H.T, Edwards, T.A.
Deposit date:2010-09-28
Release date:2011-10-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Kinked Beta-Strands Mediate High-Affinity Recognition of Mrna Targets by the Germ-Cell Regulator Dazl
Proc.Natl.Acad.Sci.USA, 108, 2011
2XS2
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Crystal structure of the RRM domain of mouse Deleted in azoospermia-like in complex with RNA, UUGUUCUU
Descriptor: 5'-R(*UP*UP*GP*UP*UP*CP*UP*U)-3', DELETED IN AZOOSPERMIA-LIKE, ZINC ION
Authors:Jenkins, H.T, Edwards, T.A.
Deposit date:2010-09-24
Release date:2011-10-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Kinked beta-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL.
Proc. Natl. Acad. Sci. U.S.A., 108, 2011
2YH1
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Model of human U2AF65 tandem RRM1 and RRM2 domains with eight-site uridine binding
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', SPLICING FACTOR U2AF 65 KDA SUBUNIT
Authors:Mackereth, C.D, Madl, T, Simon, B, Zanier, K, Gasch, A, Sattler, M.
Deposit date:2011-04-26
Release date:2011-07-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af
Nature, 475, 2011
2YH0
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Solution structure of the closed conformation of human U2AF65 tandem RRM1 and RRM2 domains
Descriptor: SPLICING FACTOR U2AF 65 KDA SUBUNIT
Authors:Mackereth, C.D, Madl, T, Simon, B, Zanier, K, Gasch, A, Sattler, M.
Deposit date:2011-04-26
Release date:2011-07-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af
Nature, 475, 2011
2YKA
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RRM domain of mRNA export adaptor REF2-I bound to HVS ORF57 peptide
Descriptor: 52 KDA IMMEDIATE-EARLY PHOSPHOPROTEIN, RNA AND EXPORT FACTOR-BINDING PROTEIN 2
Authors:Tunnicliffe, R.B, Hautbergue, G.M, Kalra, P, Wilson, S.A, Golovanov, A.P.
Deposit date:2011-05-26
Release date:2012-06-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Competitive and Cooperative Interactions Mediate RNA Transfer from Herpesvirus Saimiri Orf57 to the Mammalian Export Adaptor Alyref.
Plos Pathog., 10, 2014
1S79
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Solution structure of the central RRM of human La protein
Descriptor: Lupus La protein
Authors:Alfano, C, Sanfelice, D, Babon, J, Kelly, G, Jacks, A, Curry, S, Conte, M.R.
Deposit date:2004-01-29
Release date:2004-04-06
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein.
Nat.Struct.Mol.Biol., 11, 2004
1SJF
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Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Cobalt Hexammine solution
Descriptor: COBALT HEXAMMINE(III), Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A
Authors:Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A conformational switch controls hepatitis delta virus ribozyme catalysis.
Nature, 429, 2004
1U1Q
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Crystal Structure of UP1 Complexed With d(TTAGGGTTA(DI)GG); A Human Telomeric Repeat Containing Inosine
Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(OIP)*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Shamoo, Y.
Deposit date:2004-07-15
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
1U6F
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NMR solution structure of TcUBP1, a single RBD-unit from Trypanosoma cruzi
Descriptor: RNA-binding protein UBP1
Authors:Volpon, L, D'orso, I, Frasch, A, Gehring, K.
Deposit date:2004-07-29
Release date:2005-01-25
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR Structural Study of TcUBP1, a Single RRM Domain Protein from Trypanosoma cruzi: Contribution of a beta Hairpin to RNA Binding
Biochemistry, 44, 2005
1U1P
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Crystal Structure of UP1 Complexed With d(TTAGGGTTA 2PR GG); A Human Telomeric Repeat Containing 2-aminopurine
Descriptor: 5'-D(*T*TP*AP*GP*GP*GP*TP*TP*AP*(2PR)P*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Shamoo, Y.
Deposit date:2004-07-15
Release date:2004-09-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
1U1M
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Crystal Structure of UP1 Complexed With d(TTAGGGTTA 7GU GG); A Human Telomeric Repeat Containing 7-deaza-guanine
Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(7GU)P*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Shamoo, Y.
Deposit date:2004-07-15
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
1U1R
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Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(2PR)G); A Human Telomeric Repeat Containing 2-aminopurine
Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*(2PR)P*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Shamoo, Y.
Deposit date:2004-07-15
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
1U1L
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Crystal Structure of UP1 Complexed With d(TTAGGGTT PRN GGG); A Human Telomeric Repeat Containing nebularine
Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*(PRN)P*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Shamoo, Y.
Deposit date:2004-07-15
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
1U1O
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Crystal Structure of UP1 Complexed With d(TTAGGGTTAG(DI)G); A Human Telomeric Repeat Containing Inosine
Descriptor: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*GP*(OIP)*G)-3', Heterogeneous nuclear ribonucleoprotein A1
Authors:Myers, J.C, Shamoo, Y.
Deposit date:2004-07-15
Release date:2004-09-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
1U2F
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SOLUTION STRUCTURE OF THE FIRST RNA-BINDING DOMAIN OF HU2AF65
Descriptor: PROTEIN (SPLICING FACTOR U2AF 65 KD SUBUNIT)
Authors:Ito, T, Muto, Y, Green, M.R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1999-05-26
Release date:1999-08-20
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structures of the first and second RNA-binding domains of human U2 small nuclear ribonucleoprotein particle auxiliary factor (U2AF(65)).
EMBO J., 18, 1999

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