PDB: 3712 resultsInfo pagesStatus searchChemie searchBIRD

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9BV1	M2A Midnolin-Proteasome (translocating) Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Gao, J, Yip, M.C.J, Shao, S. Deposit date: 2024-05-19 Release date: 2025-06-11 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis for nuclear protein degradation by the midnolin-proteasome pathway To Be Published
9BW4	TXNL1-bound proteasome Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Gao, J, Yip, M.C.J, Shao, S. Deposit date: 2024-05-20 Release date: 2025-06-11 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structure of the TXNL1-bound proteasome To Be Published
9BV3	M1B Midnolin-Proteasome Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Gao, J, Yip, M.C.J, Shao, S. Deposit date: 2024-05-19 Release date: 2025-06-11 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis for nuclear protein degradation by the midnolin-proteasome pathway To Be Published
9BUI	M1A Midnolin-Proteasome (with Ubl) Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Gao, J, Yip, M.C.J, Shao, S. Deposit date: 2024-05-17 Release date: 2025-06-11 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural basis for nuclear protein degradation by the midnolin-proteasome pathway To Be Published
7W3I	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SB_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-18 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3M	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD5_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-18 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3H	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3B	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED5_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3G	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.0_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2024-10-30 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W39	Structure of USP14-bound human 26S proteasome in state EA2.1_UBL Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W37	Structure of USP14-bound human 26S proteasome in state EA1_UBL Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (3 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3C	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED0_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3K	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SD4_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2024-10-30 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3J	Structure of USP14-bound human 26S proteasome in substrate-inhibited state SC_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2024-10-30 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3A	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED4_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2024-10-30 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W3F	Structure of USP14-bound human 26S proteasome in substrate-engaged state ED1_USP14 Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
7W38	Structure of USP14-bound human 26S proteasome in state EA2.0_UBL Descriptor: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... Authors: Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. Deposit date: 2021-11-25 Release date: 2022-05-04 Last modified: 2024-11-20 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: USP14-regulated allostery of the human proteasome by time-resolved cryo-EM. Nature, 605, 2022
9E8N	Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt3 at top of spiral staircase Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Arkinson, C, Gee, C.L, Martin, A. Deposit date: 2024-11-05 Release date: 2024-12-04 Method: ELECTRON MICROSCOPY (3.62 Å) Cite: Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1. Biorxiv, 2024
9E8J	Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt1 at top of spiral staircase Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Arkinson, C, Gee, C.L, Martin, A. Deposit date: 2024-11-05 Release date: 2024-12-04 Method: ELECTRON MICROSCOPY (3.47 Å) Cite: Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1. Biorxiv, 2024
9E8I	Human proteasome in resting state conformation bound to TXNL1 in Forward conformation Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Arkinson, C, Gee, C.L, Martin, A. Deposit date: 2024-11-05 Release date: 2024-12-04 Method: ELECTRON MICROSCOPY (2.87 Å) Cite: Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1. Biorxiv, 2024
9E8Q	Nub1/Fat10-processing human 26S proteasome with Rpt2 at top of spiral staircase Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Arkinson, C, Gee, C.L, Martin, A. Deposit date: 2024-11-05 Release date: 2024-12-04 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1. Biorxiv, 2024
9E8G	Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt5 at top of spiral staircase Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Arkinson, C, Gee, C.L, Martin, A. Deposit date: 2024-11-05 Release date: 2024-12-04 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1. Biorxiv, 2024
9E8H	Human proteasome in resting state conformation bound to TXNL1 in backward conformation Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Arkinson, C, Gee, C.L, Martin, A. Deposit date: 2024-11-05 Release date: 2024-12-04 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1. Biorxiv, 2024
9E8L	Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt4 at top of spiral staircase Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Arkinson, C, Gee, C.L, Martin, A. Deposit date: 2024-11-05 Release date: 2024-12-04 Method: ELECTRON MICROSCOPY (3.59 Å) Cite: Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1. Biorxiv, 2024
9E8O	Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt2 at top of spiral staircase and partially unfolded Eos Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome complex subunit SEM1, ... Authors: Arkinson, C, Gee, C.L, Martin, A. Deposit date: 2024-11-05 Release date: 2024-12-04 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural landscape of AAA+ ATPase motor states in the substrate-degrading human 26S proteasome reveals conformation-specific binding of TXNL1. Biorxiv, 2024

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