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1OPH
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BU of 1oph by Molmil
NON-COVALENT COMPLEX BETWEEN ALPHA-1-PI-PITTSBURGH AND S195A TRYPSIN
Descriptor: Alpha-1-antitrypsin precursor, Trypsinogen, cationic precursor
Authors:Dementiev, A, Simonovic, M, Volz, K, Gettins, P.G.
Deposit date:2003-03-05
Release date:2003-08-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Canonical inhibitor-like interactions explain reactivity of alpha1-proteinase inhibitor Pittsburgh and antithrombin with proteinases
J.Biol.Chem., 278, 2003
1TB6
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BU of 1tb6 by Molmil
2.5A Crystal Structure of the Antithrombin-Thrombin-Heparin Ternary Complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-sulfonato-beta-D-glucopyranose-(1-4)-2,3-di-O-methyl-6-O-sulfonato-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-alpha-D-glucopyranose-(1-4)-2,3,6-tri-O-methyl-beta-D-glucopyranose-(1-4)-2,3-di-O-methyl-6-O-sulfonato-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-alpha-L-idopyranuronic acid-(1-4)-methyl 3-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, W, Johnson, D.J, Esmon, C.T, Huntington, J.A.
Deposit date:2004-05-19
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin.
Nat.Struct.Mol.Biol., 11, 2004
1EZX
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BU of 1ezx by Molmil
CRYSTAL STRUCTURE OF A SERPIN:PROTEASE COMPLEX
Descriptor: ALPHA-1-ANTITRYPSIN, TRYPSIN
Authors:Huntington, J.A, Carrell, R.W.
Deposit date:2000-05-12
Release date:2000-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of a serpin-protease complex shows inhibition by deformation.
Nature, 407, 2000
3H5C
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BU of 3h5c by Molmil
X-Ray Structure of Protein Z-Protein Z Inhibitor Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein Z-dependent protease inhibitor, Vitamin K-dependent protein Z, ...
Authors:Dementiev, A.A, Huang, X, Olson, S.T, Gettins, P.G.W.
Deposit date:2009-04-21
Release date:2010-04-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa.
J.Biol.Chem., 285, 2010
2X0B
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BU of 2x0b by Molmil
Crystal structure of human angiotensinogen complexed with renin
Descriptor: ANGIOTENSINOGEN, RENIN
Authors:Zhou, A, Wei, Z, Yan, Y, Carrell, R.W, Read, R.J.
Deposit date:2009-12-08
Release date:2010-10-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4.33 Å)
Cite:A Redox Switch in Angiotensinogen Modulates Angiotensin Release.
Nature, 468, 2010
6I3F
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BU of 6i3f by Molmil
Crystal structure of the complex of human angiotensinogen and renin at 2.55 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensinogen, ...
Authors:Yan, Y, Read, R.J.
Deposit date:2018-11-06
Release date:2018-12-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis for the specificity of renin-mediated angiotensinogen cleavage.
J. Biol. Chem., 294, 2019

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