PDB: 92869 resultsInfo pagesStatus searchChemie searchBIRD

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1BC0	RECOMBINANT RAT ANNEXIN V, W185A MUTANT Descriptor: ANNEXIN V, CALCIUM ION, SULFATE ION Authors: Mo, Y.D, Swairjo, M.A, Li, C.W, Head, J.F, Seaton, B.A. Deposit date: 1998-05-04 Release date: 1998-11-25 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components. Biochemistry, 37, 1998
1BEM	INTERACTION BETWEEN PROXIMAL AND DISTALS REGIONS OF CYTOCHROME C PEROXIDASE Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE Authors: Kraut, M.A.M.J. Deposit date: 1998-05-16 Release date: 1998-10-21 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Interaction between Proximal and Distals Regions of Cytochrome C Peroxidase To be Published
4GSW	Crystal structure of ubiquitin from Entamoeba histolytica to 2.15 Angstrom Descriptor: SULFATE ION, Ubiquitin Authors: Bosch, D.E, Siderovski, D.P. Deposit date: 2012-08-28 Release date: 2012-12-12 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structural Determinants of Ubiquitin Conjugation in Entamoeba histolytica. J.Biol.Chem., 288, 2013
2RJ7	B-specific alpha-1,3-galactosyltransferase G176R S235G mutant (AABB) + UDPGal + Deoxy-acceptor Descriptor: GALACTOSE-URIDINE-5'-DIPHOSPHATE, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MANGANESE (II) ION, ... Authors: Evans, S.V, Alfaro, J.A. Deposit date: 2007-10-14 Release date: 2008-02-05 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.7 Å) Cite: ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes. J.Biol.Chem., 283, 2008
4H5V	HSC70 NBD with Mg Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ... Authors: Stec, B. Deposit date: 2012-09-18 Release date: 2014-03-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
4CQK	Crystal structure of ligand-bound NaD1 Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, FLOWER-SPECIFIC DEFENSIN, SULFATE ION, ... Authors: Lay, F.T, Mills, G.M, Poon, I.K.H, Baxter, A.A, Hulett, M.D, Kvansakul, M. Deposit date: 2014-02-17 Release date: 2014-04-16 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Phosphoinositide-Mediated Oligomerization of a Defensin Induces Cell Lysis. Elife, 3, 2014
4H5R	HSC70 NBD with Na, Cl and glycerol Descriptor: CHLORIDE ION, GLYCEROL, Heat shock cognate 71 kDa protein, ... Authors: Stec, B. Deposit date: 2012-09-18 Release date: 2014-03-19 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.64 Å) Cite: New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
4H6T	Crystal structure of prethrombin-2 mutant E14eA/D14lA/E18A/S195A Descriptor: PHOSPHATE ION, Prothrombin Authors: Pozzi, N, Chen, Z, Zapata, F, Pelc, L.A, Di Cera, E. Deposit date: 2012-09-19 Release date: 2013-03-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Autoactivation of thrombin precursors. J.Biol.Chem., 288, 2013
1TFT	NMR Structure of an Antagonists of the XIAP-Caspase-9 Interaction Complexed to the BIR3 domain of XIAP Descriptor: 1-[3,3-DIMETHYL-2-(2-METHYLAMINO-PROPIONYLAMINO)-BUTYRYL]-4-PHENOXY-PYRROLIDINE-2-CARBOXYLIC ACID(1,2,3,4-TETRAHYDRO-NAPHTHALEN-1-YL)-AMIDE, Baculoviral IAP repeat-containing protein 4, ZINC ION Authors: Oost, T.K, Sun, C, Armstrong, R.C, Al-Assaad, A.S, Betz, S.F, Deckwerth, T.L, Elmore, S.W, Meadows, R.P, Olejniczak, E.T, Oleksijew, A.K, Oltersdorf, T, Rosenberg, S.H, Shoemaker, A.R, Zou, H, Fesik, S.W. Deposit date: 2004-05-27 Release date: 2005-05-03 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer. J.Med.Chem., 47, 2004
1T8W	Crystal Structure of E. coli AMP Nucleosidase Descriptor: AMP nucleosidase Authors: Zhang, Y, Cottet, S.E, Ealick, S.E. Deposit date: 2004-05-13 Release date: 2004-08-17 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure of Escherichia coli AMP Nucleosidase Reveals Similarity to Nucleoside Phosphorylases STRUCTURE, 12, 2004
1BCY	RECOMBINANT RAT ANNEXIN V, T72K MUTANT Descriptor: ANNEXIN V, CALCIUM ION, SULFATE ION Authors: Mo, Y.D, Swairjo, M.A, Li, C.W, Head, J.F, Seaton, B.A. Deposit date: 1998-05-04 Release date: 1998-11-25 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Mutational and crystallographic analyses of interfacial residues in annexin V suggest direct interactions with phospholipid membrane components. Biochemistry, 37, 1998
1T79	Crystal structure of the androgen receptor ligand binding domain in complex with a FxxLW motif Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, FxxLW motif peptide Authors: Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J. Deposit date: 2004-05-08 Release date: 2004-08-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Recognition and accommodation at the androgen receptor coactivator binding interface. Plos Biol., 2, 2004
1T8S	Crystal Structure of E.coli AMP Nucleosidase complexed with formicin 5'-monophosphate Descriptor: AMP nucleosidase, FORMYCIN-5'-MONOPHOSPHATE Authors: Zhang, Y, Cottet, S.E, Ealick, S.E. Deposit date: 2004-05-13 Release date: 2004-08-17 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of Escherichia coli AMP Nucleosidase Reveals Similarity to Nucleoside Phosphorylases STRUCTURE, 12, 2004
4H6S	Crystal structure of thrombin mutant E14eA/D14lA/E18A/S195A Descriptor: Prothrombin, SODIUM ION Authors: Pozzi, N, Chen, Z, Zapata, F, Pelc, L.A, Di Cera, E. Deposit date: 2012-09-19 Release date: 2013-03-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.19 Å) Cite: Autoactivation of thrombin precursors. J.Biol.Chem., 288, 2013
2RJ6	B-specific alpha-1,3-galactosyltransferase G176R S235G mutant (AABB) + H-antigen disaccharide Descriptor: Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, octyl 2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-galactopyranoside Authors: Evans, S.V, Alfaro, J.A. Deposit date: 2007-10-14 Release date: 2008-02-05 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.41 Å) Cite: ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes. J.Biol.Chem., 283, 2008
4PZ5	Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of BBK32 from Borrelia burgdorferi Descriptor: Fibronectin, Fibronectin-binding protein BBK32 Authors: Harris, G, Potts, J.R. Deposit date: 2014-03-28 Release date: 2014-07-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Borrelia burgdorferi Protein BBK32 Binds to Soluble Fibronectin via the N-terminal 70-kDa Region, Causing Fibronectin to Undergo Conformational Extension. J.Biol.Chem., 289, 2014
4COF	Crystal structure of a human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BENZAMIDINE, CHLORIDE ION, ... Authors: Miller, P.S, Aricescu, A.R. Deposit date: 2014-01-28 Release date: 2014-06-04 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.97 Å) Cite: Crystal Structure of a Human Gabaa Receptor Nature, 512, 2014
1TFQ	NMR Structure of an Antagonists of the XIAP-Caspase-9 Interaction Complexed to the BIR3 domain of XIAP Descriptor: Baculoviral IAP repeat-containing protein 4, N-METHYLALANYL-3-METHYLVALYL-N-(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PROLINAMIDE, ZINC ION Authors: Oost, T.K, Sun, C, Armstrong, R.C, Al-Assaad, A.S, Betz, S.F, Deckwerth, T.L, Elmore, S.W, Meadows, R.P, Olejniczak, E.T, Oleksijew, A, Oltersdorf, T, Rosenberg, S.H, Shoemaker, A.R, Zou, H, Fesik, S.W. Deposit date: 2004-05-27 Release date: 2004-09-07 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Discovery of Potent Antagonists of the Antiapoptotic Protein XIAP for the Treatment of Cancer. J.Med.Chem., 47, 2004
1SVE	Crystal Structure of Protein Kinase A in Complex with Azepane Derivative 1 Descriptor: (4R)-4-(2-FLUORO-6-HYDROXY-3-METHOXY-BENZOYL)-BENZOIC ACID (3R)-3-[(PYRIDINE-4-CARBONYL)AMINO]-AZEPAN-4-YL ESTER, N-OCTANOYL-N-METHYLGLUCAMINE, SODIUM ION, ... Authors: Breitenlechner, C.B, Wegge, T, Berillon, L, Graul, K, Marzenell, K, Friebe, W.-G, Thomas, U, Schumacher, R, Huber, R, Engh, R.A, Masjost, B. Deposit date: 2004-03-29 Release date: 2005-03-29 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Structure-based optimization of novel azepane derivatives as PKB inhibitors J.Med.Chem., 47, 2004
4HFP	Structure of thrombin mutant S195a bound to the active site inhibitor argatroban Descriptor: (2R,4R)-4-methyl-1-(N~2~-{[(3S)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonyl}-L-arginyl)piperidine-2-carboxylic acid, Prothrombin, SODIUM ION Authors: Pozzi, N, Chen, Z, Zapata, F, Lin, W, Barranco-Medina, S, Pelc, L.A, Di Cera, E. Deposit date: 2012-10-05 Release date: 2013-03-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Autoactivation of thrombin precursors. J.Biol.Chem., 288, 2013
1FSF	GLUCOSAMINE-6-PHOSPHATE DEAMINASE FROM E.COLI, T CONFORMER, AT 1.9A RESOLUTION Descriptor: GLUCOSAMINE-6-PHOSPHATE DEAMINASE Authors: Rudino-Pinera, E, Morales-Arrieta, S, Rojas-Trejo, S.P, Horjales, E. Deposit date: 2000-09-08 Release date: 2002-01-04 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural flexibility, an essential component of the allosteric activation in Escherichia coli glucosamine-6-phosphate deaminase. Acta Crystallogr.,Sect.D, 58, 2002
2RJ5	B-specific alpha-1,3-galactosyltransferase G176R S235G mutant (AABB) +UDP Descriptor: GLYCEROL, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, MANGANESE (II) ION, ... Authors: Evans, S.V, Alfaro, J.A. Deposit date: 2007-10-14 Release date: 2008-02-05 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.45 Å) Cite: ABO(H) blood group A and B glycosyltransferases recognize substrate via specific conformational changes. J.Biol.Chem., 283, 2008
1PC3	Crystal structure of the extracellular phosphate ABC transport receptor (PstS-1) and immunodominant antigen of M. tuberculosis. Descriptor: PHOSPHATE ION, Phosphate-binding protein 1 Authors: Vyas, N.K, Vyas, M.N, Quiocho, F.A. Deposit date: 2003-05-15 Release date: 2004-05-18 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Crystal structure of M tuberculosis ABC phosphate transport receptor: specificity and charge compensation dominated by ion-dipole interactions. Structure, 11, 2003
1OQH	Crystal Structure of the R124A mutant of the N-lobe human transferrin Descriptor: CARBONATE ION, FE (III) ION, POTASSIUM ION, ... Authors: Baker, H.M, He, Q.-Y, Brigg, S.K, Mason, A.B, N Baker, E. Deposit date: 2003-03-10 Release date: 2003-03-18 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin Biochemistry, 42, 2003
2CIB	High throughput screening and x-ray crystallography assisted evaluation of small molecule scaffolds for CYP51 inhibitors Descriptor: (2S)-2-[(2,1,3-BENZOTHIADIAZOL-4-YLSULFONYL)AMINO]-2-PHENYL-N-PYRIDIN-4-YLACETAMIDE, CYTOCHROME P450 51, PROTOPORPHYRIN IX CONTAINING FE Authors: Podust, L.M, Kim, Y, Yermalitskaya, L.V, Von Kries, J.P, Waterman, M.R. Deposit date: 2006-03-17 Release date: 2007-07-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Small Molecule Scaffolds for Cyp51 Inhibitors Identified by High Throughput Screening and Defined by X-Ray Crystallography Antimicrob.Agents Chemother., 51, 2007

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