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PDB: 127 results

4NYH
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Orthorhombic crystal form of pir1 dual specificity phosphatase core
Descriptor: CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase
Authors:Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
Deposit date:2013-12-10
Release date:2014-01-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
5M43
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Crystal structure of Yvh1 phosphatase domain from Chaetomium thermophilum
Descriptor: GLYCEROL, NITRATE ION, Putative uncharacterized protein
Authors:Ahmed, Y.L, Sinning, I.
Deposit date:2016-10-18
Release date:2016-11-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.646 Å)
Cite:Interaction network of the ribosome assembly machinery from a eukaryotic thermophile.
Protein Sci., 26, 2017
2E0T
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Crystal structure of catalytic domain of dual specificity phosphatase 26, MS0830 from Homo sapiens
Descriptor: Dual specificity phosphatase 26
Authors:Xie, Y, Kishishita, S, Murayama, K, Hori-Takemoto, C, Chen, L, Liu, Z.J, Wang, B.C, Shirozu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-10-13
Release date:2007-10-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:High-resolution crystal structure of the catalytic domain of human dual-specificity phosphatase 26.
Acta Crystallogr.,Sect.D, 69, 2013
4R30
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Structure of human laforin dual specificity phosphatase domain
Descriptor: BETA-MERCAPTOETHANOL, Laforin, SULFATE ION
Authors:Sankhala, R.S, Koksal, A.C, Cingolani, G.
Deposit date:2014-08-13
Release date:2014-12-31
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dimeric quaternary structure of human laforin.
J.Biol.Chem., 290, 2015
2ESB
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BU of 2esb by Molmil
Crystal structure of human DUSP18
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, Dual specificity protein phosphatase 18
Authors:Kim, S.J, Ryu, S.E, Jeong, D.G, Cho, Y.H, Yoon, T.S, Kim, J.H.
Deposit date:2005-10-25
Release date:2006-06-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of human DSP18, a member of the dual-specificity protein tyrosine phosphatase family.
Acta Crystallogr.,Sect.D, 62, 2006
3EMU
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BU of 3emu by Molmil
Crystal structure of a leucine rich repeat and phosphatase domain containing protein from Entamoeba histolytica
Descriptor: SULFATE ION, leucine rich repeat and phosphatase domain containing protein
Authors:Bonanno, J.B, Gilmore, M, Bain, K.T, Hu, S, Ozyurt, S, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2008-09-25
Release date:2008-10-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a leucine rich repeat and phosphatase domain containing protein from Entamoeba histolytica
To be Published
3F81
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Interaction of VHR with SA3
Descriptor: 2-[(5~{E})-5-[[3-[4-(2-fluoranylphenoxy)phenyl]-1-phenyl-pyrazol-4-yl]methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acid, Dual specificity protein phosphatase 3
Authors:Wu, S, Mutelin, T, Tautz, L.
Deposit date:2008-11-11
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells.
J.Med.Chem., 52, 2009
3EZZ
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Crystal Structure of human MKP-2
Descriptor: Dual specificity protein phosphatase 4, SULFATE ION
Authors:Jeong, D.G, Jung, S.K, Ryu, S.E, Kim, S.J.
Deposit date:2008-10-24
Release date:2009-08-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the catalytic domain of human MKP-2 reveals a 24-mer assembly.
Proteins, 76, 2009
3S4E
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Crystal Structrue of a Novel Mitogen-activated Protein Kinase Phosphatase, SKRP1
Descriptor: Dual specificity protein phosphatase 19, PHOSPHATE ION, SULFATE ION
Authors:Wei, C.H, Ryu, S.Y, Jeon, Y.H, Jeong, D.G, Kim, S.J, Ryu, S.E.
Deposit date:2011-05-19
Release date:2012-04-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Crystal structure of a novel mitogen-activated protein kinase phosphatase, SKRP1.
Proteins, 79, 2011
1I9T
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CRYSTAL STRUCTURE OF THE OXIDIZED RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME
Descriptor: CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ...
Authors:Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A.
Deposit date:2001-03-20
Release date:2001-05-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
7Y4E
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Crystal structure of DUSP10 mutant_N130A
Descriptor: Dual specificity protein phosphatase 10
Authors:Hu, I.C, Lyu, P.C.
Deposit date:2022-06-14
Release date:2023-06-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal structure of DUSP10 mutant_N130A
To Be Published
7Y4D
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BU of 7y4d by Molmil
Crystal structure of DUSP10 mutant_S95A
Descriptor: Dual specificity protein phosphatase 10
Authors:Hu, I.C, Lyu, P.C.
Deposit date:2022-06-14
Release date:2023-06-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal structure of DUSP10 mutant_S95A
To Be Published
7Y4C
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Crystal structure of DUSP10
Descriptor: Dual specificity protein phosphatase 10
Authors:Hu, I.C, Lyu, P.C.
Deposit date:2022-06-14
Release date:2023-06-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal structure of DUSP10
To Be Published
7Y4B
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BU of 7y4b by Molmil
Crystal structure of DUSP10 mutant_D59A
Descriptor: Dual specificity protein phosphatase 10
Authors:Hu, I.C, Lyu, P.C.
Deposit date:2022-06-14
Release date:2023-06-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal structure of DUSP10 mutant_D59A
To Be Published
3CM3
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BU of 3cm3 by Molmil
High Resolution Crystal Structure of the Vaccinia Virus Dual-Specificity Phosphatase VH1
Descriptor: BETA-MERCAPTOETHANOL, Dual specificity protein phosphatase, PHOSPHATE ION
Authors:Koksal, A.C, Cingolani, G.
Deposit date:2008-03-20
Release date:2009-02-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Dimeric Quaternary Structure of the Prototypical Dual Specificity Phosphatase VH1.
J.Biol.Chem., 284, 2009
3RGO
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BU of 3rgo by Molmil
Crystal Structure of PTPMT1
Descriptor: Protein-tyrosine phosphatase mitochondrial 1, SULFATE ION
Authors:Xiao, J, Engel, J.L.
Deposit date:2011-04-08
Release date:2011-07-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.928 Å)
Cite:Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
1I9S
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BU of 1i9s by Molmil
CRYSTAL STRUCTURE OF THE RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME
Descriptor: CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ...
Authors:Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A.
Deposit date:2001-03-20
Release date:2001-05-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
3RGQ
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BU of 3rgq by Molmil
Crystal Structure of PTPMT1 in complex with PI(5)P
Descriptor: (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate, Protein-tyrosine phosphatase mitochondrial 1
Authors:Xiao, J, Engel, J.L.
Deposit date:2011-04-08
Release date:2011-07-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3RZ2
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Crystal of Prl-1 complexed with peptide
Descriptor: Prl-1 (PTP4A1), Protein tyrosine phosphatase type IVA 1
Authors:Zhang, Z.-Y, Liu, D, Bai, Y.
Deposit date:2011-05-11
Release date:2011-10-26
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein.
J.Biol.Chem., 286, 2011
1J4X
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BU of 1j4x by Molmil
HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE C124S MUTANT-PEPTIDE COMPLEX
Descriptor: DDE(AHP)(TPO)G(PTR)VATR, DUAL SPECIFICITY PROTEIN PHOSPHATASE 3
Authors:Schumacher, M.A, Todd, J.L, Tanner, K.G, Denu, J.M.
Deposit date:2001-12-13
Release date:2001-12-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for the recognition of a bisphosphorylated MAP kinase peptide by human VHR protein Phosphatase.
Biochemistry, 41, 2002
1M3G
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SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF MAPK PHOSPHATASE PAC-1: INSIGHTS INTO SUBSTRATE-INDUCED ENZYMATIC ACTIVATION
Descriptor: DUAL SPECIFICITY PROTEIN PHOSPHATASE 2
Authors:Farooq, A, Zhou, M.-M.
Deposit date:2002-06-27
Release date:2003-06-27
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution Structure of the MAPK Phosphatase PAC-1 Catalytic Domain Insights into Substrate-Induced Enzymatic Activation of MKP
Structure, 11, 2003
4D3R
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Crystal structure of point mutated DUSP19 (I187A)
Descriptor: DUAL SPECIFICITY PROTEIN PHOSPHATASE 19, SULFATE ION
Authors:Jeon, T.J, Nam, K.T, Ryu, S.E.
Deposit date:2014-10-23
Release date:2015-11-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural Analysis of Activity-Modulating Mutations of Dusp19
Biodesign, 3, 2015
4D3Q
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crystal structure of point mutated DUSP19 (R156A)
Descriptor: DUAL SPECIFICITY PROTEIN PHOSPHATASE 19, SULFATE ION
Authors:Jeon, T.J, Nam, K.T, Ryu, S.E.
Deposit date:2014-10-23
Release date:2015-11-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structural Analysis of Activity-Modulating Mutations of Dusp19
Biodesign, 3, 2015
4D3P
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crystal structure of point mutated DUSP19 (C150A)
Descriptor: DUAL SPECIFICITY PROTEIN PHOSPHATASE 19, SULFATE ION
Authors:Jeon, T.J, Nam, K.T, Ryu, S.E.
Deposit date:2014-10-23
Release date:2015-11-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Structural Analysis of Activity-Modulating Mutations of Dusp19
Biodesign, 3, 2015
4B04
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Crystal structure of the Catalytic Domain of Human DUSP26 (C152S)
Descriptor: DUAL SPECIFICITY PROTEIN PHOSPHATASE 26
Authors:Won, E.-Y, Lee, D.Y, Park, S.G, Yokoyama, S, Kim, S.J, Chi, S.-W.
Deposit date:2012-06-28
Release date:2013-05-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.205 Å)
Cite:High-Resolution Crystal Structure of the Catalytic Domain of Human Dual-Specificity Phosphatase 26
Acta Crystallogr.,Sect.D, 69, 2013

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