7ODX
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6JRQ
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![BU of 6jrq by Molmil](/molmil-images/mine/6jrq) | Crystal structure of adenylosuccinate synthetase, PurA, from Thermus thermophilus | Descriptor: | 1,2-ETHANEDIOL, Adenylosuccinate synthetase, INOSINIC ACID | Authors: | Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2019-04-05 | Release date: | 2020-04-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of adenylosuccinate synthetase, PurA, from Thermus thermophilus HB8 To Be Published
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5K7X
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3UE9
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6RM2
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![BU of 6rm2 by Molmil](/molmil-images/mine/6rm2) | Deoxyguanylosuccinate synthase (DgsS) structure with ATP, IMP, Magnesium | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Adenylosuccinate synthetase, INOSINIC ACID, ... | Authors: | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | Deposit date: | 2019-05-04 | Release date: | 2020-06-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP, IMP, Magnesium at 2.5 Angstrom resolution To Be Published
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6ZXQ
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![BU of 6zxq by Molmil](/molmil-images/mine/6zxq) | Adenylosuccinate Synthetase from H. pylori in complex with HDA, GDP, IMO, Mg | Descriptor: | 6-O-PHOSPHORYL INOSINE MONOPHOSPHATE, Adenylosuccinate synthetase, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Bubic, A, Stefanic, Z. | Deposit date: | 2020-07-30 | Release date: | 2021-08-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The pursuit of new alternative ways to eradicate Helicobacter pylori continues: Detailed characterization of interactions in the adenylosuccinate synthetase active site Int.J.Biol.Macromol., 2023
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2V40
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![BU of 2v40 by Molmil](/molmil-images/mine/2v40) | Human Adenylosuccinate synthetase isozyme 2 in complex with GDP | Descriptor: | ADENYLOSUCCINATE SYNTHETASE ISOZYME 2, GUANOSINE-5'-DIPHOSPHATE | Authors: | Welin, M, Moche, M, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Tresaugues, L, van den Berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC) | Deposit date: | 2007-06-27 | Release date: | 2007-07-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Human Adenylosuccinate Synthetase Isozyme 2 in Complex with Gdp To be Published
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7PVO
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![BU of 7pvo by Molmil](/molmil-images/mine/7pvo) | Adenylosuccinate Synthetase from H. pylori in complex with IMP | Descriptor: | Adenylosuccinate synthetase, INOSINIC ACID, SULFATE ION | Authors: | Narczyk, M, Bzowska, A, Maksymiuk, W. | Deposit date: | 2021-10-05 | Release date: | 2022-11-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The pursuit of new alternative ways to eradicate Helicobacter pylori continues: Detailed characterization of interactions in the adenylosuccinate synthetase active site. Int.J.Biol.Macromol., 226, 2023
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3HID
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![BU of 3hid by Molmil](/molmil-images/mine/3hid) | Crystal structure of adenylosuccinate synthetase from Yersinia pestis CO92 | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, Adenylosuccinate synthetase | Authors: | Zhang, R, Zhou, M, Peterson, S, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2009-05-19 | Release date: | 2009-06-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The crystal structure of the adenylosuccinate synthetase from Yersinia pestis CO92 To be Published
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7VF6
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![BU of 7vf6 by Molmil](/molmil-images/mine/7vf6) | The crystal structure of PurZ0 | Descriptor: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ... | Authors: | Tong, Y, Zhang, Y. | Deposit date: | 2021-09-10 | Release date: | 2023-05-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.703 Å) | Cite: | Alternative Z-genome biosynthesis pathway shows evolutionary progression from Archaea to phage. Nat Microbiol, 8, 2023
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6TNH
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![BU of 6tnh by Molmil](/molmil-images/mine/6tnh) | Deoxyguanylosuccinate synthase (DgsS) quaternary structure with AMPPcP, dGMP, Asp, Magnesium at 2.21 Angstrom resolution | Descriptor: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ASPARTIC ACID, Adenylosuccinate synthetase, ... | Authors: | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | Deposit date: | 2019-12-08 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes. Science, 372, 2021
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3R7T
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![BU of 3r7t by Molmil](/molmil-images/mine/3r7t) | Crystal Structure of Adenylosuccinate Synthetase from Campylobacter jejuni | Descriptor: | Adenylosuccinate synthetase, CHLORIDE ION, CITRIC ACID, ... | Authors: | Kim, Y, Gu, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-03-23 | Release date: | 2011-04-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Adenylosuccinate Synthetase from
Campylobacter jejuni To be Published
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1IWE
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![BU of 1iwe by Molmil](/molmil-images/mine/1iwe) | IMP Complex of the Recombinant Mouse-Muscle Adenylosuccinate Synthetase | Descriptor: | ACETATE ION, Adenylosuccinate Synthetase, INOSINIC ACID, ... | Authors: | Iancu, C.V, Borza, T, Fromm, H.J, Honzatko, R.B. | Deposit date: | 2002-05-04 | Release date: | 2002-08-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | IMP, GTP, and 6-phosphoryl-IMP complexes of recombinant mouse muscle adenylosuccinate synthetase. J.Biol.Chem., 277, 2002
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1SOO
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![BU of 1soo by Molmil](/molmil-images/mine/1soo) | ADENYLOSUCCINATE SYNTHETASE INHIBITED BY HYDANTOCIDIN 5'-MONOPHOSPHATE | Descriptor: | ADENYLOSUCCINATE SYNTHETASE, BETA-MERCAPTOETHANOL, HYDANTOCIDIN-5'-PHOSPHATE, ... | Authors: | Cowan-Jacob, S.W. | Deposit date: | 1996-05-07 | Release date: | 1997-09-04 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The mode of action and the structure of a herbicide in complex with its target: binding of activated hydantocidin to the feedback regulation site of adenylosuccinate synthetase. Proc.Natl.Acad.Sci.USA, 93, 1996
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1J4B
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![BU of 1j4b by Molmil](/molmil-images/mine/1j4b) | Recombinant Mouse-Muscle Adenylosuccinate Synthetase | Descriptor: | adenylosuccinate synthetase | Authors: | Iancu, C.V, Borza, T, Choe, J.Y, Fromm, H.J, Honzatko, R.B. | Deposit date: | 2001-09-07 | Release date: | 2001-11-21 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Recombinant mouse muscle adenylosuccinate synthetase: overexpression, kinetics, and crystal structure. J.Biol.Chem., 276, 2001
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6FM3
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![BU of 6fm3 by Molmil](/molmil-images/mine/6fm3) | Deoxyguanylosuccinate synthase (DgsS) structure with ADP at 1.9 Angstrom resolution | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Adenylosuccinate synthetase, CHLORIDE ION | Authors: | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | Deposit date: | 2018-01-30 | Release date: | 2019-06-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP0, dGMP, Magnesium at 2.3 Angstrom resolution To Be Published
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1SON
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![BU of 1son by Molmil](/molmil-images/mine/1son) | ADENYLOSUCCINATE SYNTHETASE IN COMPLEX WITH THE NATURAL FEEDBACK INHIBITOR AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENYLOSUCCINATE SYNTHETASE, BETA-MERCAPTOETHANOL | Authors: | Cowan-Jacob, S.W. | Deposit date: | 1996-05-07 | Release date: | 1997-09-04 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The mode of action and the structure of a herbicide in complex with its target: binding of activated hydantocidin to the feedback regulation site of adenylosuccinate synthetase. Proc.Natl.Acad.Sci.USA, 93, 1996
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4M9D
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![BU of 4m9d by Molmil](/molmil-images/mine/4m9d) | The Crystal structure of an adenylosuccinate synthetase from Bacillus anthracis str. Ames Ancestor in complex with AMP. | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Adenylosuccinate synthetase, ... | Authors: | Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-08-14 | Release date: | 2013-08-28 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.821 Å) | Cite: | The Crystal structure of an adenylosuccinate synthetase from Bacillus anthracis str. Ames Ancestor in complex with AMP. To be Published
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5I34
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![BU of 5i34 by Molmil](/molmil-images/mine/5i34) | Adenylosuccinate synthetase from Cryptococcus neoformans complexed with GDP and IMP | Descriptor: | Adenylosuccinate synthetase, GUANOSINE-5'-DIPHOSPHATE, INOSINIC ACID | Authors: | Blundell, R.D, Williams, S.J, Ericsson, D, Fraser, J.A, Kobe, B. | Deposit date: | 2016-02-09 | Release date: | 2016-08-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans. Acs Infect Dis., 2, 2016
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5I33
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![BU of 5i33 by Molmil](/molmil-images/mine/5i33) | Unligated adenylosuccinate synthetase from Cryptococcus neoformans | Descriptor: | Adenylosuccinate synthetase | Authors: | Blundell, R.D, Williams, S.J, Ericsson, D, Fraser, J.A, Kobe, B. | Deposit date: | 2016-02-09 | Release date: | 2016-08-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Disruption of de Novo Adenosine Triphosphate (ATP) Biosynthesis Abolishes Virulence in Cryptococcus neoformans. Acs Infect Dis., 2, 2016
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6FM0
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![BU of 6fm0 by Molmil](/molmil-images/mine/6fm0) | Deoxyguanylosuccinate synthase (DgsS) and ATP structure at 1.7 Angstrom resolution | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Adenylosuccinate synthetase | Authors: | Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. | Deposit date: | 2018-01-29 | Release date: | 2019-06-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes. Science, 372, 2021
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6BS7
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1ADI
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![BU of 1adi by Molmil](/molmil-images/mine/1adi) | STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE AT PH 6.5 AND 25 DEGREES CELSIUS | Descriptor: | ADENYLOSUCCINATE SYNTHETASE | Authors: | Silva, M.M, Poland, B.W, Hoffman, C.M, Fromm, H.J, Honzatko, R.B. | Deposit date: | 1995-09-14 | Release date: | 1996-06-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Refined crystal structures of unligated adenylosuccinate synthetase from Escherichia coli. J.Mol.Biol., 254, 1995
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6C25
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1ADE
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![BU of 1ade by Molmil](/molmil-images/mine/1ade) | STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE PH 7 AT 25 DEGREES CELSIUS | Descriptor: | ADENYLOSUCCINATE SYNTHETASE | Authors: | Silva, M.M, Poland, B.W, Hoffman, C.M, Fromm, H.J, Honzatko, R.B. | Deposit date: | 1995-09-14 | Release date: | 1996-01-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Refined crystal structures of unligated adenylosuccinate synthetase from Escherichia coli. J.Mol.Biol., 254, 1995
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