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PDB: 189 results

6VSU
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BU of 6vsu by Molmil
Arginase from Arabidopsis thaliana in Complex with Ornithine
Descriptor: Arginase 1, mitochondrial, DI(HYDROXYETHYL)ETHER, ...
Authors:Sekula, B.
Deposit date:2020-02-11
Release date:2020-08-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Neighboring Subunit Is Engaged to Stabilize the Substrate in the Active Site of Plant Arginases.
Front Plant Sci, 11, 2020
5CEV
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BU of 5cev by Molmil
ARGINASE FROM BACILLUS CALDEVELOX, L-LYSINE COMPLEX
Descriptor: GUANIDINE, LYSINE, MANGANESE (II) ION, ...
Authors:Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N.
Deposit date:1999-03-16
Release date:1999-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
3RLA
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BU of 3rla by Molmil
ALTERING THE BINUCLEAR MANGANESE CLUSTER OF ARGINASE DIMINISHES THERMOSTABILITY AND CATALYTIC FUNCTION
Descriptor: ARGINASE, MANGANESE (II) ION
Authors:Scolnick, L.R, Kanyo, Z.F, Christianson, D.W.
Deposit date:1997-05-07
Release date:1998-05-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Altering the binuclear manganese cluster of arginase diminishes thermostability and catalytic function.
Biochemistry, 36, 1997
7OI1
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BU of 7oi1 by Molmil
Crystal structure of Synechocystis sp PCC6803 guanidinium hydrolase
Descriptor: 1,2-ETHANEDIOL, CACODYLATE ION, CHLORIDE ION, ...
Authors:Fleming, J.R, Mayans, O.M.
Deposit date:2021-05-11
Release date:2021-12-15
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of a Ni 2+ -dependent guanidine hydrolase in bacteria.
Nature, 603, 2022
2ZAV
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BU of 2zav by Molmil
Arginase I (homo sapiens): native and unliganded structure at 1.70 A resolution
Descriptor: Arginase-1, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2007-10-11
Release date:2007-10-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster
J.Am.Chem.Soc., 129, 2007
5RLA
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BU of 5rla by Molmil
ALTERING THE BINUCLEAR MANGANESE CLUSTER OF ARGINASE DIMINISHES THERMOSTABILITY AND CATALYTIC FUNCTION
Descriptor: ARGINASE, MANGANESE (II) ION
Authors:Scolnick, L.R, Kanyo, Z.F, Christianson, D.W.
Deposit date:1997-05-07
Release date:1998-05-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Altering the binuclear manganese cluster of arginase diminishes thermostability and catalytic function.
Biochemistry, 36, 1997
8AUP
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BU of 8aup by Molmil
Structure of hARG1 with a novel inhibitor.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-[(1~{R},3~{R},4~{S})-3-azanyl-3-carboxy-4-[(dimethylamino)methyl]cyclohexyl]ethyl-$l^{3}-oxidanyl-bis(oxidanyl)boron, Arginase-1, ...
Authors:Napiorkowska-Gromadzka, A, Nowak, E, Nowotny, M.
Deposit date:2022-08-25
Release date:2023-03-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Arginase 1/2 Inhibitor OATD-02: From Discovery to First-in-man Setup in Cancer Immunotherapy.
Mol.Cancer Ther., 22, 2023
6DKT
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BU of 6dkt by Molmil
Crystal structure of Arginase from Bacillus subtilis
Descriptor: Arginase, MANGANESE (II) ION
Authors:Lewis, M.C, Hollingsworth, S.A, Holden, J.K, Poulos, T.L.
Deposit date:2018-05-30
Release date:2018-09-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structure of Arginase from Bacillus subtilis at 2.08 Angstroms resolution
To Be Published
4CEV
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BU of 4cev by Molmil
ARGINASE FROM BACILLUS CALDEVELOX, L-ORNITHINE COMPLEX
Descriptor: GUANIDINE, L-ornithine, MANGANESE (II) ION, ...
Authors:Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N.
Deposit date:1999-03-15
Release date:1999-04-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
2RLA
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BU of 2rla by Molmil
ALTERING THE BINUCLEAR MANGANESE CLUSTER OF ARGINASE DIMINISHES THERMOSTABILITY AND CATALYTIC FUNCTION
Descriptor: ARGINASE, MANGANESE (II) ION
Authors:Scolnick, L.R, Kanyo, Z.F, Christianson, D.W.
Deposit date:1997-05-07
Release date:1998-05-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Altering the binuclear manganese cluster of arginase diminishes thermostability and catalytic function.
Biochemistry, 36, 1997
6VST
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BU of 6vst by Molmil
Arginase from Medicago truncatula in complex with ornithine
Descriptor: Arginase, L-ornithine, MANGANESE (II) ION
Authors:Sekula, B.
Deposit date:2020-02-11
Release date:2020-08-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:The Neighboring Subunit Is Engaged to Stabilize the Substrate in the Active Site of Plant Arginases.
Front Plant Sci, 11, 2020
6VSS
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BU of 6vss by Molmil
Arginase from Medicago truncatula
Descriptor: Arginase, MANGANESE (II) ION
Authors:Sekula, B.
Deposit date:2020-02-11
Release date:2020-08-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:The Neighboring Subunit Is Engaged to Stabilize the Substrate in the Active Site of Plant Arginases.
Front Plant Sci, 11, 2020
2AEB
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BU of 2aeb by Molmil
Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in immune response.
Descriptor: 2(S)-AMINO-6-BORONOHEXANOIC ACID, Arginase 1, MANGANESE (II) ION
Authors:Di Costanzo, L, Sabio, G, Mora, A, Rodriguez, P.C, Ochoa, A.C, Centeno, F, Christianson, D.W.
Deposit date:2005-07-21
Release date:2005-09-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Crystal structure of human arginase I at 1.29 A resolution and exploration of inhibition in the immune response.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2A0M
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BU of 2a0m by Molmil
Arginase superfamily protein from Trypanosoma cruzi
Descriptor: ARGINASE SUPERFAMILY PROTEIN, CHLORIDE ION
Authors:Arakaki, T.L, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-06-16
Release date:2005-07-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Structural genomics of pathogenic protozoa: an overview.
Methods Mol.Biol., 426, 2008
6NFP
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BU of 6nfp by Molmil
1.7 Angstrom Resolution Crystal Structure of Arginase from Bacillus subtilis subsp. subtilis str. 168
Descriptor: 1,2-ETHANEDIOL, Arginase, CHLORIDE ION, ...
Authors:Minasov, G, Wawrzak, Z, Evdokimova, E, Grimshaw, S, Kwon, K, Savchenko, A, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-12-20
Release date:2019-01-02
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:1.7 Angstrom Resolution Crystal Structure of Arginase from Bacillus subtilis subsp. subtilis str. 168
To Be Published
3GMZ
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BU of 3gmz by Molmil
Crystal of human arginase in complex with L-ornithine. Resolution 1.43 A.
Descriptor: Arginase-1, L-ornithine, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2009-03-15
Release date:2010-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Binding of alpha,alpha-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design
J.Med.Chem., 54, 2011
6NBK
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BU of 6nbk by Molmil
Crystal structure of Arginase from Bacillus cereus
Descriptor: Arginase, CALCIUM ION, MANGANESE (II) ION
Authors:Chang, C, Evdokimova, E, Mcchesney, M, Joachimiak, A, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2018-12-07
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal structure of Arginase from Bacillus cereus
To Be Published
5HJA
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BU of 5hja by Molmil
Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABHDP
Descriptor: (R)-2-amino-6-borono-2-(1-(3,4-dichlorobenzyl)piperidin-4-yl)hexanoic acid, Arginase, GLYCEROL, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2016-01-13
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structures of Leishmania mexicana arginase complexed with alpha , alpha-disubstituted boronic amino-acid inhibitors.
Acta Crystallogr F Struct Biol Commun, 72, 2016
5HJ9
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BU of 5hj9 by Molmil
Crystal structure of Leishmania mexicana arginase in complex with inhibitor ABHPE
Descriptor: 1,2-ETHANEDIOL, Arginase, GLYCEROL, ...
Authors:Hai, Y, Christianson, D.W.
Deposit date:2016-01-13
Release date:2016-04-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Crystal structures of Leishmania mexicana arginase complexed with alpha , alpha-disubstituted boronic amino-acid inhibitors.
Acta Crystallogr F Struct Biol Commun, 72, 2016
1CEV
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BU of 1cev by Molmil
ARGINASE FROM BACILLUS CALDOVELOX, NATIVE STRUCTURE AT PH 5.6
Descriptor: MANGANESE (II) ION, PROTEIN (ARGINASE)
Authors:Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N.
Deposit date:1999-03-12
Release date:1999-04-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily.
Structure Fold.Des., 7, 1999
1D3V
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BU of 1d3v by Molmil
CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH 2(S)-AMINO-6-BORONOHEXANOIC ACID, AN L-ARGININE ANALOG
Descriptor: 2(S)-AMINO-6-BORONOHEXANOIC ACID, MANGANESE (II) ION, PROTEIN (ARGINASE)
Authors:Cox, J.D, Kim, N.N, Traish, A.M, Christianson, D.W.
Deposit date:1999-10-01
Release date:1999-11-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Arginase-boronic acid complex highlights a physiological role in erectile function.
Nat.Struct.Biol., 6, 1999
9IQ9
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BU of 9iq9 by Molmil
Crystal structure of Copper-bound N(omega)-hydroxy-L-arginine hydrolase with reduced Cys86
Descriptor: COPPER (I) ION, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Oda, K, Matoba, Y.
Deposit date:2024-07-12
Release date:2024-07-24
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Copper inactivates DcsB by oxidation of the Cys86 to cysteine sulfinic aicd
To Be Published
9FEK
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BU of 9fek by Molmil
Crystal structure of guanidinase from Nitrospira inopinata
Descriptor: MANGANESE (II) ION, NICKEL (II) ION, Putative agmatinase 2, ...
Authors:Puehringer, D, Mccarthy, A.
Deposit date:2024-05-20
Release date:2024-08-14
Last modified:2024-08-28
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Growth of complete ammonia oxidizers on guanidine.
Nature, 2024
3GN0
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BU of 3gn0 by Molmil
Crystal structure of human arginase I in complex with difluoromethylornithine (DFMO)
Descriptor: ALPHA-DIFLUOROMETHYLORNITHINE, Arginase-1, MANGANESE (II) ION
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2009-03-15
Release date:2010-02-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of alpha,alpha-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design
J.Med.Chem., 54, 2011
8D27
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BU of 8d27 by Molmil
Arginase Domain of Ornithine Decarboxylase/Arginase from Fusobacterium nucleatum
Descriptor: Arginase
Authors:Chan, A.C, Kolesnikov, M, Murphy, M.E.
Deposit date:2022-05-27
Release date:2022-07-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species.
Biochemistry, 61, 2022

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PDB entries from 2024-09-18

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