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PDB: 60 results
1IZ1
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BU of 1iz1 by Molmil
CRYSTAL STRUCTURE OF CBNR, A LYSR FAMILY TRANSCRIPTIONAL REGULATOR
Descriptor: LysR-type regulatory protein
Authors:Muraoka, S, Okumura, R, Ogawa, N, Miyashita, K, Senda, T.
Deposit date:2002-09-18
Release date:2003-05-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of a Full-length LysR-type Transcriptional Regulator, CbnR: Unusual Combination of Two Subunit Forms and Molecular Bases for Causing and Changing DNA Bend
J.Mol.Biol., 328, 2003
1IXC
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BU of 1ixc by Molmil
Crystal structure of CbnR, a LysR family transcriptional regulator
Descriptor: LysR-type regulatory protein
Authors:Muraoka, S, Okumura, R, Ogawa, N, Miyashita, K, Senda, T.
Deposit date:2002-06-18
Release date:2003-06-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Full-length LysR-type Transcriptional Regulator, CbnR: Unusual Combination of Two Subunit Forms and Molecular Bases for Causing and Changing DNA Bend
J.Mol.Biol., 328, 2003
7QA0
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BU of 7qa0 by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound 1456
Descriptor: Multiple virulence factor regulator MvfR, ~{N}-[[2-(3-chloranyl-4-propan-2-yloxy-phenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine
Authors:Schmelz, S, Blankenfeldt, W.
Deposit date:2021-11-15
Release date:2022-11-23
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Discovery and Optimization of Thiazole-Based Quorum Sensing Inhibitors as Potent Blockers of Pseudomonas Aeruginosa Pathogenicity
Ssrn, 2024
7QAV
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BU of 7qav by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound N-((2-(4-cyclopropylphenyl)thiazol-5-yl)methyl)-2-(trifluoromethyl)pyridin-4-amine
Descriptor: Multiple virulence factor regulator MvfR, ~{N}-[[2-(4-cyclopropylphenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine
Authors:Schmelz, S, Blankenfeldt, W.
Deposit date:2021-11-17
Release date:2022-11-30
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Discovery and Optimization of Thiazole-Based Quorum Sensing Inhibitors as Potent Blockers of Pseudomonas Aeruginosa Pathogenicity
Ssrn, 2024
7QA3
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BU of 7qa3 by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound N-((2-(4-phenoxyphenyl)thiazol-5-yl)methyl)-2-(trifluoromethyl)pyridin-4-amine
Descriptor: Multiple virulence factor regulator MvfR, N-[[2-(4-phenoxyphenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine
Authors:Schmelz, S, Blankenfeldt, W.
Deposit date:2021-11-15
Release date:2022-11-23
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Discovery and Optimization of Thiazole-Based Quorum Sensing Inhibitors as Potent Blockers of Pseudomonas Aeruginosa Pathogenicity
Ssrn, 2024
2H9B
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BU of 2h9b by Molmil
Crystal structure of the effector binding domain of a BenM variant (BenM R156H/T157S)
Descriptor: CHLORIDE ION, HTH-type transcriptional regulator benM, SULFATE ION
Authors:Ezezika, O.C, Craven, S.H, Neidle, E.L, Momany, C.
Deposit date:2006-06-09
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Inducer responses of BenM, a LysR-type transcriptional regulator from Acinetobacter baylyi ADP1.
Mol.Microbiol., 72, 2009
6G1B
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BU of 6g1b by Molmil
Corynebacterium glutamicum OxyR, oxidized form
Descriptor: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, FORMIC ACID, HYDROGEN PEROXIDE, ...
Authors:Young, D.R, Pedre, B.P, Messens, J.M.
Deposit date:2018-03-21
Release date:2018-12-05
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6G4R
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BU of 6g4r by Molmil
Corynebacterium glutamicum OxyR C206S mutant, H2O2-bound
Descriptor: 1,2-ETHANEDIOL, HYDROGEN PEROXIDE, Hydrogen peroxide-inducible genes activator, ...
Authors:Young, D.R, Pedre, B.P, Messens, J.M.
Deposit date:2018-03-28
Release date:2018-12-05
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6G1D
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BU of 6g1d by Molmil
Corynebacterium glutamicum OxyR C206 mutant
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ...
Authors:Young, D.R, Pedre, B.P, Messens, J.M.
Deposit date:2018-03-21
Release date:2018-12-05
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.992 Å)
Cite:Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4GWO
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BU of 4gwo by Molmil
Crystal structure of ligand binding domain of LysR family member,CysB in complex with sulfate from Salmonella typhimurium LT2
Descriptor: GLYCEROL, HTH-type transcriptional regulator CysB, SULFATE ION
Authors:Mittal, M, Singh, A.K, Kumaran, S.
Deposit date:2012-09-03
Release date:2013-09-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Crystal structure of ligand binding domain of LysR family member,CysB in complex with sulfate from Salmonella typhimurium LT2
To be Published
2H99
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BU of 2h99 by Molmil
Crystal structure of the effector binding domain of a BenM variant (R156H,T157S)
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Ezezika, O.C, Craven, S.H, Neidle, E.L, Momany, C.
Deposit date:2006-06-09
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Inducer responses of BenM, a LysR-type transcriptional regulator from Acinetobacter baylyi ADP1.
Mol.Microbiol., 72, 2009
2H98
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BU of 2h98 by Molmil
Crystal structure of the effector binding domain of a CatM variant, CatM(V158M)
Descriptor: CHLORIDE ION, HTH-type transcriptional regulator catM
Authors:Ezezika, O.C, Neidle, E.L, Momany, C.
Deposit date:2006-06-09
Release date:2007-06-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the altered regulatory roles of three LysR-type transcritional variants of CatM and BenM: CatM(V158M), CatM(R156H) and BenM(R156H/T157S)
To be Published
7DMW
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BU of 7dmw by Molmil
Crystal structure of CcpC regulatory domain in complex with citrate from Bacillus amyloliquefaciens
Descriptor: CITRATE ANION, CcpC
Authors:Chen, J, Wang, L, Shang, F, Liu, W, Chen, Y, Lan, J, Bu, T, Bai, X, Xu, Y.
Deposit date:2020-12-08
Release date:2021-10-27
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Functional and structural analysis of catabolite control protein C that responds to citrate.
Sci Rep, 11, 2021
7DWN
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BU of 7dwn by Molmil
Crystal structure of Vibrio fischeri DarR in complex with DNA reveals the transcriptional activation mechanism of LTTR family members
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Predicted DNA-binding transcriptional regulator
Authors:Wang, W.W, Wu, H, He, J.H, Yu, F.
Deposit date:2021-01-17
Release date:2021-07-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Crystal structure details of Vibrio fischeri DarR and mutant DarR-M202I from LTTR family reveals their activation mechanism.
Int.J.Biol.Macromol., 183, 2021
7DWO
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BU of 7dwo by Molmil
Crystal structure of Vibrio fischeri DarR in complex with DNA reveals the transcriptional activation mechanism of LTTR family members
Descriptor: Predicted DNA-binding transcriptional regulator
Authors:Wang, W.W, Wu, H, He, J.H, Yu, F.
Deposit date:2021-01-17
Release date:2021-07-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.611 Å)
Cite:Crystal structure details of Vibrio fischeri DarR and mutant DarR-M202I from LTTR family reveals their activation mechanism.
Int.J.Biol.Macromol., 183, 2021
7YHJ
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BU of 7yhj by Molmil
Effector binding domain of LysR-Type transcription factor LrhA from E. coli
Descriptor: DI(HYDROXYETHYL)ETHER, Probable HTH-type transcriptional regulator LrhA, SULFATE ION
Authors:Xie, C, Jiang, X.
Deposit date:2022-07-13
Release date:2022-08-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.237 Å)
Cite:Effector binding domain of LysR-Type transcription factor LrhA from E. coli
To Be Published
7D98
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BU of 7d98 by Molmil
Crystal structure of full-length CbnR complexed with the target DNA complex
Descriptor: DNA (56-mer), LysR-type regulatory protein
Authors:Senda, M, Giannopoulou, E, Senda, T.
Deposit date:2020-10-12
Release date:2021-03-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Crystal structure of the full-length LysR-type transcription regulator CbnR in complex with promoter DNA.
Febs J., 288, 2021
7W08
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BU of 7w08 by Molmil
Itaconate inducible LysR-Type Transcriptional regulator (ITCR) in APO form, Space group P1.
Descriptor: Transcriptional regulator, LysR family
Authors:Sun, P.K, Wang, B, Li, X.J.
Deposit date:2021-11-17
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages.
Nat Commun, 13, 2022
7W06
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BU of 7w06 by Molmil
Itaconate inducible LysR-Type Transcriptional regulator (ITCR) in complex with itaconate (SeMet labeled), Space group C121.
Descriptor: 2-methylidenebutanedioic acid, CHLORIDE ION, SULFATE ION, ...
Authors:Sun, P.K, Wang, B, Wang, Z.X, Qi, S, Li, X.J.
Deposit date:2021-11-17
Release date:2022-10-26
Last modified:2022-11-16
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages.
Nat Commun, 13, 2022
7W07
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BU of 7w07 by Molmil
Itaconate inducible LysR-Type Transcriptional regulator (ITCR) in complex with itaconate, Space group C121.
Descriptor: 2-methylidenebutanedioic acid, SULFATE ION, Transcriptional regulator, ...
Authors:Sun, P.K, Wang, B, Li, X.J.
Deposit date:2021-11-17
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages.
Nat Commun, 13, 2022
3HHG
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BU of 3hhg by Molmil
Structure of CrgA, a LysR-type transcriptional regulator from Neisseria meningitidis.
Descriptor: Transcriptional regulator, LysR family
Authors:Sainsbury, S, Ren, J, Owens, R.J, Stuart, D.I, Oxford Protein Production Facility (OPPF)
Deposit date:2009-05-15
Release date:2009-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators
Nucleic Acids Res., 37, 2009
3ISP
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BU of 3isp by Molmil
Crystal structure of ArgP from Mycobacterium tuberculosis
Descriptor: HTH-type transcriptional regulator Rv1985c/MT2039
Authors:Zhou, X, Lou, Z, Sheng, F, Bartlam, M, Wang, H, Rao, Z.
Deposit date:2009-08-27
Release date:2010-02-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of ArgP from Mycobacterium tuberculosis Confirms Two Distinct Conformations of Full-length LysR Transcriptional Regulators and Reveals Its Function in DNA Binding and Transcriptional Regulation.
J.Mol.Biol., 2009
3K1M
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BU of 3k1m by Molmil
Crystal Structure of full-length BenM, R156H mutant
Descriptor: CHLORIDE ION, GLYCEROL, HTH-type transcriptional regulator benM, ...
Authors:Ruangprasert, A, Momany, C, Neidle, E.L, Craven, S.H.
Deposit date:2009-09-28
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structure of Full-length BenM
To be Published
3K1P
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BU of 3k1p by Molmil
Crystal Structure of full-length BenM E226K mutant
Descriptor: HTH-type transcriptional regulator benM
Authors:Ruangprasert, A, Momany, C, Neidle, E.L, Craven, S.H.
Deposit date:2009-09-28
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Full-length BenM
To be Published
3FXQ
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BU of 3fxq by Molmil
Crystal structure of the LysR-type transcriptional regulator TsaR
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, FORMIC ACID, ...
Authors:Monferrer, D, Tralau, T, Kertesz, M.A, Kikhney, A, Svergun, D, Uson, I.
Deposit date:2009-01-21
Release date:2010-01-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural studies on the full-length LysR-type regulator TsaR from Comamonas testosteroni T-2 reveal a novel open conformation of the tetrameric LTTR fold
Mol.Microbiol., 75, 2010

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PDB entries from 2024-06-12

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