4UX2
| Cryo-EM structure of antagonist-bound E2P gastric H,K-ATPase (SCH.E2. MgF) | Descriptor: | POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA | Authors: | Abe, K, Tani, K, Fujiyoshi, Y. | Deposit date: | 2014-08-18 | Release date: | 2014-09-17 | Last modified: | 2014-11-12 | Method: | ELECTRON CRYSTALLOGRAPHY (7 Å) | Cite: | Systematic Comparison of Molecular Conformations of H+,K+-ATPase Reveals an Important Contribution of the A-M2 Linker for the Luminal Gating. J.Biol.Chem., 289, 2014
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5NCQ
| Structure of the (SR) Ca2+-ATPase bound to a Tetrahydrocarbazole and TNP-ATP | Descriptor: | (1~{S})-~{N}-[(4-bromophenyl)methyl]-7-(trifluoromethyloxy)-2,3,4,9-tetrahydro-1~{H}-carbazol-1-amine, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, POTASSIUM ION, ... | Authors: | Bublitz, M, Kjellerup, L, O'Hanlon Cohrt, K, Gordon, S, Mortensen, A.L, Clausen, J.D, Pallin, D, Hansen, J.B, Brown, W.D, Fuglsang, A, Winther, A.-M.L. | Deposit date: | 2017-03-06 | Release date: | 2018-01-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Tetrahydrocarbazoles are a novel class of potent P-type ATPase inhibitors with antifungal activity. PLoS ONE, 13, 2018
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4HQJ
| Crystal structure of Na+,K+-ATPase in the Na+-bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHOLESTEROL, MAGNESIUM ION, ... | Authors: | Nyblom, M, Reinhard, L, Gourdon, P, Nissen, P. | Deposit date: | 2012-10-25 | Release date: | 2013-10-02 | Last modified: | 2014-09-10 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | Crystal structure of Na+, K(+)-ATPase in the Na(+)-bound state. Science, 342, 2013
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4HYT
| Na,K-ATPase in the E2P state with bound ouabain and Mg2+ in the cation-binding site | Descriptor: | 1-O-decanoyl-beta-D-tagatofuranosyl beta-D-allopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Laursen, M, Yatime, L, Nissen, P, Fedosova, N.U. | Deposit date: | 2012-11-14 | Release date: | 2013-06-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.404 Å) | Cite: | Crystal structure of the high-affinity Na+,K+-ATPase-ouabain complex with Mg2+ bound in the cation binding site. Proc.Natl.Acad.Sci.USA, 110, 2013
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4H1W
| E1 structure of the (SR) Ca2+-ATPase in complex with Sarcolipin | Descriptor: | MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... | Authors: | Bublitz, M, Winther, A.-M.L, Karlsen, J, Moller, J.V, Hansen, J.B, Buch-Pedersen, M.J, Nissen, P. | Deposit date: | 2012-09-11 | Release date: | 2013-03-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasm. Nature, 495, 2013
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6XMU
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6XMS
| Structure of P5A-ATPase Spf1, AlF4-bound form | Descriptor: | MAGNESIUM ION, P5A-type ATPase, TETRAFLUOROALUMINATE ION | Authors: | Park, E, Sim, S.I. | Deposit date: | 2020-06-30 | Release date: | 2020-09-23 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase. Science, 369, 2020
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7FJQ
| Cryo EM structure of lysosomal ATPase | Descriptor: | Polyamine-transporting ATPase 13A2, SPERMINE | Authors: | Zhang, S.S. | Deposit date: | 2021-08-04 | Release date: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures and transport mechanism of human P5B type ATPase ATP13A2. Cell Discov, 7, 2021
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7FJP
| Cryo EM structure of lysosomal ATPase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Zhang, S.S. | Deposit date: | 2021-08-04 | Release date: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structures and transport mechanism of human P5B type ATPase ATP13A2. Cell Discov, 7, 2021
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7OP1
| Cryo-EM structure of P5B-ATPase E2PiAlF/SPM | Descriptor: | Cation-transporting ATPase, MAGNESIUM ION, SPERMINE, ... | Authors: | Li, P, Gourdon, P. | Deposit date: | 2021-05-28 | Release date: | 2021-06-30 | Last modified: | 2021-09-01 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure and transport mechanism of P5B-ATPases. Nat Commun, 12, 2021
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7OP8
| Cryo-EM structure of P5B-ATPase E2Pinhibit | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Cation-transporting ATPase, MAGNESIUM ION | Authors: | Li, P, Gourdon, P. | Deposit date: | 2021-05-31 | Release date: | 2021-06-30 | Last modified: | 2021-09-01 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure and transport mechanism of P5B-ATPases. Nat Commun, 12, 2021
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7OP3
| Cryo-EM structure of P5B-ATPase E2PiSPM | Descriptor: | Cation-transporting ATPase, SPERMINE | Authors: | Li, P, Gronberg, C, Wang, K.T, Salustros, N, Gourdon, P.E. | Deposit date: | 2021-05-28 | Release date: | 2021-06-30 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure and transport mechanism of P5B-ATPases. Nat Commun, 12, 2021
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7OP5
| Cryo-EM structure of P5B-ATPase E2P | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, P5B-ATPase | Authors: | Li, P, Gourdon, P. | Deposit date: | 2021-05-29 | Release date: | 2021-06-30 | Last modified: | 2021-09-01 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure and transport mechanism of P5B-ATPases. Nat Commun, 12, 2021
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6YAA
| Structure of the (SR) Ca2+-ATPase bound to the inhibitor compound CAD204520 and TNP-ATP | Descriptor: | 4-[2-[(2~{R})-2-[3-propyl-6-(trifluoromethyloxy)-1~{H}-indol-2-yl]piperidin-1-yl]ethyl]morpholine, POTASSIUM ION, SPIRO(2,4,6-TRINITROBENZENE[1,2A]-2O',3O'-METHYLENE-ADENINE-TRIPHOSPHATE, ... | Authors: | Heit, S, Marchesini, M, Gherli, A, Montanaro, A, Patrizi, L, Sorrentino, C, Pagliaro, L, Rompietti, C, Kitara, S, Olesen, C.E, Moller, J.V, Savi, M, Bocchi, L, Vilella, R, Rizzi, F, Baglione, M, Rastelli, G, Loiacona, C, La Starza, R, Mecucci, C, Stegmair, K, Aversa, F, Stilli, D, Lund Winther, A.M, Sportoletti, P, Dalby-Brown, W, Roti, G, Bublitz, M. | Deposit date: | 2020-03-11 | Release date: | 2020-05-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia. Cell Chem Biol, 27, 2020
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6YSO
| Crystal structure of the (SR) Ca2+-ATPase solved by vanadium SAD phasing | Descriptor: | CHLORIDE ION, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | Authors: | El Omari, K, Mohamad, N, Bountra, K, Duman, R, Romano, M, Schlegel, K, Kwong, H, Mykhaylyk, V, Olesen, C.E, Moller, J.V, Bublitz, M, Beis, K, Wagner, A. | Deposit date: | 2020-04-22 | Release date: | 2020-11-04 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (3.13 Å) | Cite: | Experimental phasing with vanadium and application to nucleotide-binding membrane proteins. Iucrj, 7, 2020
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1SU4
| Crystal structure of calcium ATPase with two bound calcium ions | Descriptor: | CALCIUM ION, SODIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Authors: | Toyoshima, C, Nakasako, M, Nomura, H, Ogawa, H. | Deposit date: | 2004-03-26 | Release date: | 2004-05-04 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 A resolution Nature, 405, 2000
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1T5S
| Structure of the (SR)Ca2+-ATPase Ca2-E1-AMPPCP form | Descriptor: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | Authors: | Sorensen, T.L.-M, Moller, J.V, Nissen, P. | Deposit date: | 2004-05-05 | Release date: | 2004-06-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Phosphoryl transfer and calcium ion occlusion in the calcium pump. Science, 304, 2004
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7LC3
| CryoEM Structure of KdpFABC in E1-ATP state | Descriptor: | (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | Authors: | Sweet, M.E, Larsen, C, Pedersen, B.P, Stokes, D.L. | Deposit date: | 2021-01-09 | Release date: | 2021-01-27 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Structural basis for potassium transport in prokaryotes by KdpFABC. Proc.Natl.Acad.Sci.USA, 118, 2021
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7LC6
| Cryo-EM Structure of KdpFABC in E2-P state with BeF3 | Descriptor: | (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Sweet, M.E, Larsen, C, Pedersen, B.P, Stokes, D.L. | Deposit date: | 2021-01-09 | Release date: | 2021-01-27 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis for potassium transport in prokaryotes by KdpFABC. Proc.Natl.Acad.Sci.USA, 118, 2021
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1VFP
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1T5T
| Structure of the (SR)Ca2+-ATPase Ca2-E1-ADP:AlF4- form | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Sorensen, T.L.-M, Moller, J.V, Nissen, P. | Deposit date: | 2004-05-05 | Release date: | 2004-06-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Phosphoryl transfer and calcium ion occlusion in the calcium pump. Science, 304, 2004
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5XAA
| Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E2-ALF-(TG) crystals of P21212 symmetry | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | Authors: | Norimatsu, Y, Hasegawa, K, Shimizu, N, Toyoshima, C. | Deposit date: | 2017-03-11 | Release date: | 2017-05-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Protein-phospholipid interplay revealed with crystals of a calcium pump. Nature, 545, 2017
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5XA8
| Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E1-ALF4-ADP-2CA2+ crystals | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | Authors: | Norimatsu, Y, Hasegawa, K, Shimizu, N, Toyoshima, C. | Deposit date: | 2017-03-11 | Release date: | 2017-05-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Protein-phospholipid interplay revealed with crystals of a calcium pump. Nature, 545, 2017
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5XA9
| Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E2-ALF-(TG) crystals of C2 symmetry | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | Authors: | Norimatsu, Y, Hasegawa, K, Shimizu, N, Toyoshima, C. | Deposit date: | 2017-03-11 | Release date: | 2017-06-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Protein-phospholipid interplay revealed with crystals of a calcium pump. Nature, 545, 2017
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5XA7
| Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E1-2CA2+ crystals | Descriptor: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, SODIUM ION, ... | Authors: | Norimatsu, Y, Hasegawa, K, Shimizu, N, Toyoshima, C. | Deposit date: | 2017-03-11 | Release date: | 2017-05-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Protein-phospholipid interplay revealed with crystals of a calcium pump. Nature, 545, 2017
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