2WY0
| Crystal structure of mouse angiotensinogen in the oxidised form with space group P6122 | Descriptor: | 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION | Authors: | Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. | Deposit date: | 2009-11-11 | Release date: | 2010-10-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature, 468, 2010
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2WXY
| Crystal structure of mouse angiotensinogen in the reduced form | Descriptor: | 1,2-ETHANEDIOL, ANGIOTENSINOGEN, SODIUM ION | Authors: | Zhou, A, Wei, Z, Carrell, R.W, Read, R.J. | Deposit date: | 2009-11-11 | Release date: | 2010-10-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Redox Switch in Angiotensinogen Modulates Angiotensin Release. Nature, 468, 2010
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2WXZ
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3F5N
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3FGQ
| Crystal structure of native human neuroserpin | Descriptor: | GLYCEROL, Neuroserpin | Authors: | Takehara, S, Yang, X, Mikami, B, Onda, M. | Deposit date: | 2008-12-08 | Release date: | 2009-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | The 2.1-A crystal structure of native neuroserpin reveals unique structural elements that contribute to conformational instability J.Mol.Biol., 388, 2009
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1JTI
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1JJO
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1LQ8
| Crystal structure of cleaved protein C inhibitor | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Huntington, J.A, Kjellberg, M, Stenflo, J. | Deposit date: | 2002-05-09 | Release date: | 2003-02-11 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of Protein C Inhibitor Provides Insights into Hormone Binding and Heparin Activation Structure, 11, 2003
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1JVQ
| Crystal structure at 2.6A of the ternary complex between antithrombin, a P14-P8 reactive loop peptide, and an exogenous tetrapeptide | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ... | Authors: | Zhou, A, Huntington, J.A, Lomas, D.A, Carrell, R.W, Stein, P.E. | Deposit date: | 2001-08-31 | Release date: | 2003-06-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | How small peptides block and reverse serpin polymerisation J.Mol.Biol., 342, 2004
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1LK6
| Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous tripeptide | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Zhou, A, Huntington, J.A, Lomas, D.A, Carrell, R.W, Stein, P.E. | Deposit date: | 2002-04-24 | Release date: | 2003-06-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Serpin Polymerization Is Prevented by a Hydrogen Bond Network That Is Centered on His-334 and Stabilized by Glycerol J.Biol.Chem., 278, 2003
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3DRU
| Crystal Structure of Gly117Phe Alpha1-Antitrypsin | Descriptor: | Alpha-1-antitrypsin | Authors: | Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E. | Deposit date: | 2008-07-11 | Release date: | 2009-03-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. J.Mol.Biol., 387, 2009
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3DRM
| 2.2 Angstrom Crystal Structure of Thr114Phe Alpha1-Antitrypsin | Descriptor: | Alpha-1-antitrypsin | Authors: | Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E. | Deposit date: | 2008-07-11 | Release date: | 2009-03-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. J.Mol.Biol., 387, 2009
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1LJ5
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1IZ2
| Interactions causing the kinetic trap in serpin protein folding | Descriptor: | alpha-D-glucopyranose-(1-2)-(5R)-5-[(2R)-2-hydroxynonyl]-beta-D-xylulofuranose, alpha1-antitrypsin | Authors: | Im, H, Woo, M.-S, Hwang, K.Y, Yu, M.-H. | Deposit date: | 2002-09-19 | Release date: | 2003-02-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Interactions causing the kinetic trap in serpin protein folding J.BIOL.CHEM., 277, 2002
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3DLW
| Antichymotrypsin | Descriptor: | Alpha-1-antichymotrypsin | Authors: | Feil, S.C. | Deposit date: | 2008-06-29 | Release date: | 2009-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Identification and characterization of a misfolded monomeric serpin formed at physiological temperature J.Mol.Biol., 403, 2010
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3DY0
| Crystal Structure of Cleaved PCI Bound to Heparin | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, C-terminus Plasma serine protease inhibitor, GLYCEROL, ... | Authors: | Li, W, Huntington, J.A. | Deposit date: | 2008-07-25 | Release date: | 2008-10-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The heparin binding site of protein C inhibitor is protease-dependent. J.Biol.Chem., 283, 2008
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1JMJ
| Crystal Structure of Native Heparin Cofactor II | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HEPARIN COFACTOR II, ... | Authors: | Baglin, T.P, Carrell, R.W, Church, F.C, Huntington, J.A. | Deposit date: | 2001-07-18 | Release date: | 2002-08-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism. Proc.Natl.Acad.Sci.USA, 99, 2002
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6HGF
| Crystal structure of Alpha1-antichymotrypsin variant NewBG-II: a new binding globulin in complex with cortisol | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin | Authors: | Schmidt, K, Muller, Y.A. | Deposit date: | 2018-08-23 | Release date: | 2019-05-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.651 Å) | Cite: | NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
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6HGH
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6I3I
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6I8S
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6I4V
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6I3Z
| Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin in complex with its antigen | Descriptor: | Alpha-1-antitrypsin, Fab 2H2 heavy chain, Fab 2H2 light chain, ... | Authors: | Laffranchi, M, Elliston, E.L.K, Miranda, E, Perez, J, Jagger, A.M, Fra, A, Lomas, D.A, Irving, J.A. | Deposit date: | 2018-11-08 | Release date: | 2019-11-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin. JCI Insight, 5, 2020
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6HGD
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6HGG
| Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with cortisol | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin | Authors: | Schmidt, K, Muller, Y.A. | Deposit date: | 2018-08-23 | Release date: | 2019-05-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.787 Å) | Cite: | NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy. J.Struct.Biol., 207, 2019
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