3UKX
 
 | | Mouse importin alpha: Bimax2 peptide complex | | Descriptor: | Bimax2 peptide, Importin subunit alpha-2 | | Authors: | Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. | | Deposit date: | 2011-11-10 | | Release date: | 2012-10-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
|
|
7TMY
 | |
7LEQ
 | |
5V5O
 | |
7L04
 | |
3RZ9
 | |
2YNR
 | | mImp_alphadIBB_B54NLS | | Descriptor: | B54NLS, IMPORTIN SUBUNIT ALPHA | | Authors: | Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B. | | Deposit date: | 2012-10-18 | | Release date: | 2013-01-09 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals.
Plant Cell, 24, 2012
|
|
7TMX
 | |
1Q1S
 | | Mouse Importin alpha- phosphorylated SV40 CN peptide complex | | Descriptor: | Importin alpha-2 subunit, Large T antigen | | Authors: | Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B. | | Deposit date: | 2003-07-22 | | Release date: | 2004-03-30 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
|
|
4ZDU
 | |
3ZIR
 | | minor-site specific NLS (B141) | | Descriptor: | B141NLS, IMPORTIN SUBUNIT ALPHA-2 | | Authors: | Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. | | Deposit date: | 2013-01-10 | | Release date: | 2013-08-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
|
|
7M60
 | | Structure of Mouse Importin alpha MLH1-S467A NLS Peptide Complex | | Descriptor: | DNA mismatch repair protein Mlh1 NLS peptide, Importin subunit alpha-1 | | Authors: | De Oliveira, H.C, Da Silva, T.D, Fukuda, C.A, Fontes, M.R.M. | | Deposit date: | 2021-03-25 | | Release date: | 2021-07-07 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
|
|
6D7N
 | |
8TUV
 | | Merkel Cell Polyomavirus LTA NLSm bound to importin alpha 2 | | Descriptor: | 30S ribosomal protein S11, Importin subunit alpha-1, SER-ARG-LYS-ARG-LYS-PHE | | Authors: | Cross, E.M, Forwood, J.K, Alvisi, G. | | Deposit date: | 2023-08-17 | | Release date: | 2024-02-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
|
|
5B56
 | | Crystal structure of HIV-1 VPR C-Terminal domain and DIBB-M-Importin-Alpha2 complex | | Descriptor: | Importin subunit alpha-1, Protein Vpr | | Authors: | Miyatake, H, Sanjoh, A, Matusda, G, Murakami, T, Murakami, H, Hagiwara, K, Yokoyama, M, Sato, H, Miyamoto, Y, Dohmae, N, Aida, Y. | | Deposit date: | 2016-04-25 | | Release date: | 2016-06-01 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Molecular Mechanism of HIV-1 Vpr for Binding to Importin-alpha
J.Mol.Biol., 428, 2016
|
|
3L3Q
 | | Mouse importin alpha-pepTM NLS peptide complex | | Descriptor: | CITRATE ANION, Importin subunit alpha-2, pepTM | | Authors: | Takeda, A.A.S, Kobe, B, Fontes, M.R.M. | | Deposit date: | 2009-12-17 | | Release date: | 2010-04-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Probing the specificity of binding to the major nuclear localization sequence-binding site of importin-alpha using oriented peptide library screening.
J.Biol.Chem., 285, 2010
|
|
3UKZ
 | | Mouse importin alpha: mouse CBP80 cNLS complex | | Descriptor: | Importin subunit alpha-2, Nuclear cap-binding protein subunit 1 | | Authors: | Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. | | Deposit date: | 2011-11-10 | | Release date: | 2012-10-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
|
|
5E6Q
 | | Importin alpha binding to XRCC1 NLS peptide | | Descriptor: | CHLORIDE ION, DNA repair protein XRCC1 NLS peptide, GLYCEROL, ... | | Authors: | Pedersen, L.C, Kirby, T.W, Gassman, N.R, Smith, C.E, Gabel, S.A, Sobhany, M, Wilson, S.H, London, R.E. | | Deposit date: | 2015-10-10 | | Release date: | 2015-10-28 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.305 Å) | | Cite: | Nuclear Localization of the DNA Repair Scaffold XRCC1: Uncovering the Functional Role of a Bipartite NLS.
Sci Rep, 5, 2015
|
|
4U5N
 | | IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR | | Descriptor: | Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzyl]-L-lysyl-N-[(1R,2S,3R)-1-{[(2R)-1-amino-1-oxo-3-phenylpropan-2-yl]amino}-1,3-dihydroxybutan-2-yl]glycinamide | | Authors: | Stewart, M, Valkov, E, Holvey, R.S. | | Deposit date: | 2014-07-25 | | Release date: | 2015-05-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design.
Chemmedchem, 10, 2015
|
|
3UKY
 | | Mouse importin alpha: yeast CBP80 cNLS complex | | Descriptor: | Importin subunit alpha-2, Nuclear cap-binding protein complex subunit 1 | | Authors: | Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B. | | Deposit date: | 2011-11-10 | | Release date: | 2012-10-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
|
|
3UVU
 | |
5GXW
 | | Importin and NuMA complex | | Descriptor: | Importin subunit alpha-1, Peptide from Nuclear mitotic apparatus protein 1 | | Authors: | Chang, C.-C, Huang, T.-L, Hsia, K.-C. | | Deposit date: | 2016-09-20 | | Release date: | 2017-10-04 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.394 Å) | | Cite: | Regulation of mitotic spindle assembly factor NuMA by Importin-beta
J. Cell Biol., 216, 2017
|
|
8SG7
 | |
5K9S
 | | Importin-alpha in complex with HNF1-beta peptide | | Descriptor: | HNF1 beta A splice variant 2, Importin subunit alpha-1 | | Authors: | Wiedmann, M.M, Aibara, S, Spring, D.R, Stewart, M, Brenton, J. | | Deposit date: | 2016-06-01 | | Release date: | 2016-11-23 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Importin-alpha in complex with HNF1-beta peptide
To Be Published
|
|
3ZIP
 | | minor-site specific NLS (A58) | | Descriptor: | A58NLS, IMPORTIN SUBUNIT ALPHA-2 | | Authors: | Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. | | Deposit date: | 2013-01-10 | | Release date: | 2013-08-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
|
|
