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PDB: 136 results

8G6L
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BU of 8g6l by Molmil
HIV-1 capsid lattice bound to IP6, pH 6.2
Descriptor: Capsid protein
Authors:Highland, C.M, Dick, R.A.
Deposit date:2023-02-15
Release date:2023-05-03
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
8TY6
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BU of 8ty6 by Molmil
Disulfide-stabilized HIV-1 CA hexamer in complex with PQBP1 Nt
Descriptor: Capsid protein p24
Authors:Piacentini, J, Pornillos, O, Ganser-Pornillos, B.K.
Deposit date:2023-08-24
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular Determinants of PQBP1 Binding to the HIV-1 Capsid Lattice.
J.Mol.Biol., 436, 2024
8D3B
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BU of 8d3b by Molmil
Hexameric HIV-1 (M-group) Q50Y/R120 mutant
Descriptor: Capsid protein p24
Authors:Jacques, D.A, Govasli, M.L, Pinotsis, N, James, L.C.
Deposit date:2022-06-01
Release date:2022-10-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Evasion of cGAS and TRIM5 defines pandemic HIV.
Nat Microbiol, 7, 2022
8GDV
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BU of 8gdv by Molmil
Structure of M66I mutant of disulfide stabilized HIV-1 CA hexamer in complex with CPSF6 peptide and IP6
Descriptor: Cleavage and polyadenylation specificity factor subunit 6, Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
Authors:Briganti, L, Schope, L, Kvaratskhelia, M.
Deposit date:2023-03-06
Release date:2024-03-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of M66I mutant of disulfide stabilized HIV-1 CA hexamer in complex with CPSF6 peptide and IP6
To Be Published
7RJ4
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BU of 7rj4 by Molmil
Co-crystal structure of lenacapavir bound to N74D mutant of disulfide stabilized HIV-1 CA hexamer
Descriptor: CAPSID PROTEIN P24, CHLORIDE ION, IODIDE ION, ...
Authors:Bester, S.M, Kvaratskhelia, M.
Deposit date:2021-07-20
Release date:2022-07-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Structural and Mechanistic Bases of Viral Resistance to HIV-1 Capsid Inhibitor Lenacapavir.
Mbio, 13, 2022
8CL1
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BU of 8cl1 by Molmil
HIV-1 mature capsid hexamer from CA-IP6 CLPs, bound to CPSF6 peptide.
Descriptor: Cleavage and polyadenylation specificity factor subunit 6, Gag polyprotein
Authors:Stacey, J.C.V, Briggs, J.A.G.
Deposit date:2023-02-16
Release date:2023-04-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
6ECN
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BU of 6ecn by Molmil
HIV-1 CA 1/2-hexamer-EE
Descriptor: HIV-1 CA
Authors:Summers, B.J, Xiong, Y.
Deposit date:2018-08-08
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms.
Cell Host Microbe, 26, 2019
6EC2
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BU of 6ec2 by Molmil
Structure of HIV-1 CA 1/3-hexamer
Descriptor: ACETATE ION, Capsid protein p24
Authors:Summers, B.J, Xiong, Y.
Deposit date:2018-08-07
Release date:2019-08-21
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms.
Cell Host Microbe, 26, 2019
7URN
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BU of 7urn by Molmil
Structure of HIV-1 capsid declination
Descriptor: HIV-1 capsid protein, INOSITOL HEXAKISPHOSPHATE
Authors:Pornillos, O, Ganser-Pornillos, B.K, Schirra, R.T.
Deposit date:2022-04-22
Release date:2023-02-15
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:A molecular switch modulates assembly and host factor binding of the HIV-1 capsid.
Nat.Struct.Mol.Biol., 30, 2023
8CL2
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BU of 8cl2 by Molmil
HIV-1 mature capsid pentamer from CA-IP6 CLPs bound to CPSF6 peptide
Descriptor: Gag polyprotein
Authors:Stacey, J.C.V, Briggs, J.A.G.
Deposit date:2023-02-16
Release date:2023-04-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
7N9V
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BU of 7n9v by Molmil
CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
Descriptor: Capsid protein, Nanobody-GYAR
Authors:Tripler, T.N.
Deposit date:2021-06-18
Release date:2022-06-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
To Be Published
8G6N
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BU of 8g6n by Molmil
HIV-1 capsid lattice bound to dNTPs
Descriptor: Capsid protein
Authors:Highland, C.M, Dick, R.A.
Deposit date:2023-02-15
Release date:2023-05-03
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
7N9X
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BU of 7n9x by Molmil
CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
Descriptor: Capsid protein, Nanobody, Peptidyl-prolyl cis-trans isomerase A
Authors:Gerber, E.E, Digianantonio, K.M, Tripler, T.N, Smaga, S.S, Summers, B.J, Xiong, Y.
Deposit date:2021-06-18
Release date:2022-06-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.511 Å)
Cite:CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
To Be Published
8G6K
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BU of 8g6k by Molmil
HIV-1 CA lattice bound to IP6; from capsid-like particles
Descriptor: Capsid protein
Authors:Highland, C.M, Dick, R.A.
Deposit date:2023-02-15
Release date:2023-05-03
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EJL
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BU of 8ejl by Molmil
Structure of HIV-1 capsid declination in complex with CPSF6-FG peptide
Descriptor: Cleavage and polyadenylation specificity factor subunit 6, HIV-1 capsid protein
Authors:Pornillos, O, Ganser-Pornillos, B.K, Schirra, R.T, dos Santos, N.F.B.
Deposit date:2022-09-17
Release date:2023-02-15
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:A molecular switch modulates assembly and host factor binding of the HIV-1 capsid.
Nat.Struct.Mol.Biol., 30, 2023
5L93
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BU of 5l93 by Molmil
An atomic model of HIV-1 CA-SP1 reveals structures regulating assembly and maturation
Descriptor: Capsid protein p24
Authors:Schur, F.K.M, Obr, M, Hagen, W.J.H, Wan, W, Arjen, J.J, Kirkpatrick, J.M, Sachse, C, Kraeusslich, H.-G, Briggs, J.A.G.
Deposit date:2016-06-09
Release date:2016-07-13
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation.
Science, 353, 2016
6ECO
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BU of 6eco by Molmil
Hexamer-2-Foldon HIV-1 capsid platform
Descriptor: HIV-1 capsid platform protein
Authors:Summers, B.J, Xiong, Y.
Deposit date:2018-08-08
Release date:2019-09-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms.
Cell Host Microbe, 26, 2019
5UPW
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BU of 5upw by Molmil
CryoEM Structure Refinement by Integrating NMR Chemical Shifts with Molecular Dynamics Simulations
Descriptor: Gag polyprotein
Authors:Perilla, J.R.
Deposit date:2017-02-04
Release date:2017-03-01
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (5 Å)
Cite:CryoEM Structure Refinement by Integrating NMR Chemical Shifts with Molecular Dynamics Simulations.
J Phys Chem B, 121, 2017
6VWS
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BU of 6vws by Molmil
Hexamer of Helical HIV capsid by RASTR method
Descriptor: HIV capsid protein
Authors:Zhao, H, Iqbal, N, Asturias, F, Kvaratskhelia, M, Vanblerkom, P.
Deposit date:2020-02-20
Release date:2020-10-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.08 Å)
Cite:Structural and mechanistic bases for a potent HIV-1 capsid inhibitor.
Science, 370, 2020
5MCX
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BU of 5mcx by Molmil
The structure of the mature HIV-1 CA hexamer in intact virus particles
Descriptor: Capsid protein p24
Authors:Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G.
Deposit date:2016-11-10
Release date:2016-12-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:The structure and flexibility of conical HIV-1 capsids determined within intact virions.
Science, 354, 2016
7OVR
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BU of 7ovr by Molmil
Mature HIV-1 matrix structure
Descriptor: HIV-1 matrix, MYRISTIC ACID, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
Authors:Qu, K, Ke, Z.L, Zila, V, Anders-Oesswein, M, Glass, B, Muecksch, F, Mueller, R, Schultz, C, Mueller, B, Kraeusslich, H.G, Briggs, J.A.G.
Deposit date:2021-06-15
Release date:2021-08-18
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Maturation of the matrix and viral membrane of HIV-1.
Science, 373, 2021
3GV2
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BU of 3gv2 by Molmil
X-ray Structure of Hexameric HIV-1 CA
Descriptor: Capsid protein p24,Carbon dioxide-concentrating mechanism protein CcmK homolog 4
Authors:Kelly, B.N.
Deposit date:2009-03-30
Release date:2009-06-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (7 Å)
Cite:X-ray structures of the hexameric building block of the HIV capsid.
Cell(Cambridge,Mass.), 137, 2009
7OVQ
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BU of 7ovq by Molmil
Immature HIV-1 matrix structure
Descriptor: Gag polyprotein, MYRISTIC ACID
Authors:Qu, K, Ke, Z.L, Zila, V, Anders-Oesswein, M, Glass, B, Muecksch, F, Mueller, R, Schultz, C, Mueller, B, Kraeusslich, H.G, Briggs, J.A.G.
Deposit date:2021-06-15
Release date:2021-08-18
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Maturation of the matrix and viral membrane of HIV-1.
Science, 373, 2021
5MCY
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BU of 5mcy by Molmil
The structure of the mature HIV-1 CA pentamer in intact virus particles
Descriptor: Capsid protein p24
Authors:Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G.
Deposit date:2016-11-10
Release date:2016-12-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (8.8 Å)
Cite:The structure and flexibility of conical HIV-1 capsids determined within intact virions.
Science, 354, 2016
5UP4
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BU of 5up4 by Molmil
Structure of the HIV-1 Capsid Protein and spacer peptide 1 by Cryo-EM
Descriptor: HIV-1 Capsid Protein and spacer peptide 1
Authors:Perilla, J.R, Schirra, R, Zhang, P, Schulten, K.
Deposit date:2017-02-01
Release date:2017-12-06
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Quenching protein dynamics interferes with HIV capsid maturation.
Nat Commun, 8, 2017

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PDB entries from 2024-09-11

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