6D08
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![BU of 6d08 by Molmil](/molmil-images/mine/6d08) | Crystal structure of an engineered bump-hole complex of mutant human chromobox homolog 1 (CBX1) with H3K9bn peptide | Descriptor: | Chromobox protein homolog 1, GLYCEROL, Histone H3.1, ... | Authors: | Arora, S, Horne, W.S, Islam, K. | Deposit date: | 2018-04-10 | Release date: | 2019-04-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Engineering Methyllysine Writers and Readers for Allele-Specific Regulation of Protein-Protein Interactions. J.Am.Chem.Soc., 141, 2019
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6IIT
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6D07
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8IIZ
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7MJU
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2CNX
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![BU of 2cnx by Molmil](/molmil-images/mine/2cnx) | WDR5 and Histone H3 Lysine 4 dimethyl complex at 2.1 angstrom | Descriptor: | HISTONE H3 DIMETHYL-LYSINE 4, WD-REPEAT PROTEIN 5 | Authors: | Ruthenburg, A.J, Wang, W, Graybosch, D.M, Li, H, Allis, C.D, Patel, D.J, Verdine, G.L. | Deposit date: | 2006-05-25 | Release date: | 2006-07-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Histone H3 Recognition and Presentation by the Wdr5 Module of the Mll1 Complex Nat.Struct.Mol.Biol., 13, 2006
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5FB1
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![BU of 5fb1 by Molmil](/molmil-images/mine/5fb1) | Crystal Structure of a PHD finger bound to histone H3 K9me3 peptide | Descriptor: | MALONATE ION, Nuclear autoantigen Sp-100, Peptide from Histone H3, ... | Authors: | Li, H, Zhang, X. | Deposit date: | 2015-12-13 | Release date: | 2016-05-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Multifaceted Histone H3 Methylation and Phosphorylation Readout by the Plant Homeodomain Finger of Human Nuclear Antigen Sp100C J.Biol.Chem., 291, 2016
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5IQL
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5C13
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5XTZ
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![BU of 5xtz by Molmil](/molmil-images/mine/5xtz) | Crystal structure of GAS41 YEATS bound to H3K27ac peptide | Descriptor: | ACETATE ION, THR-LYS-ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, YEATS domain-containing protein 4 | Authors: | Li, H.T, Zhao, D. | Deposit date: | 2017-06-21 | Release date: | 2018-06-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.105 Å) | Cite: | Gas41 links histone acetylation to H2A.Z deposition and maintenance of embryonic stem cell identity. Cell Discov, 4, 2018
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2OT7
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![BU of 2ot7 by Molmil](/molmil-images/mine/2ot7) | Crystal structure of JMJD2A complexed with histone H3 peptide monomethylated at Lys9 | Descriptor: | JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, NICKEL (II) ION, ... | Authors: | Kavanagh, K.L, Ng, S.S, Pilka, E, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | Deposit date: | 2007-02-07 | Release date: | 2007-03-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.135 Å) | Cite: | Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity. Nature, 448, 2007
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5OY3
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![BU of 5oy3 by Molmil](/molmil-images/mine/5oy3) | The structural basis of the histone demethylase KDM6B histone 3 lysine 27 specificity | Descriptor: | 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, FE (III) ION, ... | Authors: | Jones, S.E, Olsen, L, Gajhede, M. | Deposit date: | 2017-09-07 | Release date: | 2017-09-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.136 Å) | Cite: | Structural Basis of Histone Demethylase KDM6B Histone 3 Lysine 27 Specificity. Biochemistry, 57, 2018
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8IIY
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3U4S
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![BU of 3u4s by Molmil](/molmil-images/mine/3u4s) | Histone Lysine demethylase JMJD2A in complex with T11C peptide substrate crosslinked to N-oxalyl-D-cysteine | Descriptor: | HISTONE 3 TAIL ANALOG (T11C Peptide), Lysine-specific demethylase 4A, N-(carboxycarbonyl)-D-cysteine, ... | Authors: | Ma, J, McDonough, M.A, Schofield, C.J. | Deposit date: | 2011-10-10 | Release date: | 2012-02-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Linking of 2-Oxoglutarate and Substrate Binding Sites Enables Potent and Highly Selective Inhibition of JmjC Histone Demethylases. Angew.Chem.Int.Ed.Engl., 51, 2012
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6JOU
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![BU of 6jou by Molmil](/molmil-images/mine/6jou) | Crystal structure of the human nucleosome containing H2A.Z.1 S42R | Descriptor: | DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ... | Authors: | Horikoshi, N, Sato, K, Mizukami, Y, Kurumizaka, H. | Deposit date: | 2019-03-23 | Release date: | 2020-03-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Structure-based design of an H2A.Z.1 mutant stabilizing a nucleosome in vitro and in vivo. Biochem.Biophys.Res.Commun., 515, 2019
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8Q3E
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![BU of 8q3e by Molmil](/molmil-images/mine/8q3e) | High Resolution Structure of Nucleosome Core with Bound Foamy Virus GAG Peptide | Descriptor: | DNA (145-MER), GLY-GLY-TYR-ASN-LEU-ARG-PRO-ARG-THR-TYR-GLN-PRO-GLN-ARG-TYR-GLY-GLY-GLY, Histone H2A type 1-B/E, ... | Authors: | De Falco, L, Batchelor, L.K, Dyson, P.J, Davey, C.A. | Deposit date: | 2023-08-04 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.174 Å) | Cite: | Viral peptide conjugates for metal-warhead delivery to chromatin. Rsc Adv, 14, 2024
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3U31
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3ZG6
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![BU of 3zg6 by Molmil](/molmil-images/mine/3zg6) | The novel de-long chain fatty acid function of human sirt6 | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, GLYCEROL, NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-6, ... | Authors: | Wang, Y, Hao, Q. | Deposit date: | 2012-12-15 | Release date: | 2013-04-03 | Last modified: | 2013-04-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Sirt6 Regulates Tnf-Alpha Secretion Through Hydrolysis of Long-Chain Fatty Acyl Lysine Nature, 496, 2013
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4TN7
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![BU of 4tn7 by Molmil](/molmil-images/mine/4tn7) | Crystal structure of mouse KDM2A-H3K36ME-NO complex | Descriptor: | FE (III) ION, Lysine-specific demethylase 2A, NITRIC OXIDE, ... | Authors: | Cheng, Z. | Deposit date: | 2014-06-03 | Release date: | 2015-05-13 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36. Genes Dev., 28, 2014
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6LS6
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5AV9
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![BU of 5av9 by Molmil](/molmil-images/mine/5av9) | human nucleosome core particle | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S. | Deposit date: | 2015-06-12 | Release date: | 2015-12-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation Sci Rep, 5, 2015
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5AV8
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![BU of 5av8 by Molmil](/molmil-images/mine/5av8) | human nucleosome core particle | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S. | Deposit date: | 2015-06-12 | Release date: | 2015-12-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation Sci Rep, 5, 2015
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5B31
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![BU of 5b31 by Molmil](/molmil-images/mine/5b31) | The crystal structure of the heterotypic H2AZ/H2A nucleosome with H3.1. | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | Authors: | Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H. | Deposit date: | 2016-02-08 | Release date: | 2016-08-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A. Open Biology, 6, 2016
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6K1K
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![BU of 6k1k by Molmil](/molmil-images/mine/6k1k) | Human nucleosome core particle with H2A.X S139E variant | Descriptor: | CHLORIDE ION, DNA (145-MER), Histone H2AX, ... | Authors: | Sharma, D, De Falco, L, Davey, C.A. | Deposit date: | 2019-05-10 | Release date: | 2020-01-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome. Nat Commun, 10, 2019
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5AV6
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![BU of 5av6 by Molmil](/molmil-images/mine/5av6) | human nucleosome core particle | Descriptor: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | Authors: | Wakamori, M, Fujii, Y, Umehara, T, Yokoyama, S. | Deposit date: | 2015-06-12 | Release date: | 2015-12-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation Sci Rep, 5, 2015
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