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PDB: 228 件

4GJH
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Crystal Structure of the TRAF domain of TRAF5
分子名称: TNF receptor-associated factor 5
著者Zhang, P, Reichardt, A, Liang, H, Wang, Y, Cheng, D, Aliyari, R, Cheng, G, Liu, Y.
登録日2012-08-09
公開日2012-11-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5
Sci.Signal., 5, 2012
4PO2
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Crystal Structure of the Stress-Inducible Human Heat Shock Protein HSP70 Substrate-Binding Domain in Complex with Peptide Substrate
分子名称: HSP70 substrate peptide, Heat shock 70 kDa protein 1A/1B, PHOSPHATE ION, ...
著者Zhang, P, Leu, J.I, Murphy, M.E, George, D.L, Marmorstein, R.
登録日2014-02-24
公開日2014-08-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the stress-inducible human heat shock protein 70 substrate-binding domain in complex with Peptide substrate.
Plos One, 9, 2014
3F6G
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Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type II
分子名称: Alpha-isopropylmalate synthase, ISOLEUCINE, SULFATE ION, ...
著者Zhang, P, Ma, J, Zhao, G, Ding, J.
登録日2008-11-06
公開日2009-04-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans
Biochem.J., 421, 2009
8TEC
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Crystal structure of Kindlin2 in complex with acylated beta1 integrin peptide
分子名称: Fermitin family homolog 2, Integrin beta-1
著者Zhang, P.F, Wu, J.H.
登録日2023-07-06
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Acetyl-NPKY of integrin-beta 1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity.
Iscience, 27, 2024
8TEE
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Crystal structure of Kindlin2 in complex with K794Q mutated beta1 integrin
分子名称: Fermitin family homolog 2, Integrin beta-1
著者Zhang, P.F, Wu, J.H.
登録日2023-07-06
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Acetyl-NPKY of integrin-beta 1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity.
Iscience, 27, 2024
8XOM
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Cryo-EM structure of human ABCC4 in complex with ANP-bound in NBD1 and METHOTREXATE
分子名称: 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ...
著者Zhang, P.F, Liu, Z.
登録日2024-01-01
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport.
Febs Lett., 2024
6VGU
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Crystal structure of FERM-folded talin head domain bound to the NPLY motif of beta3-integrin
分子名称: Integrin beta-3,Talin-1
著者Zhang, P, Sun, Y, Wu, J.
登録日2020-01-09
公開日2020-12-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Crystal structure of the FERM-folded talin head reveals the determinants for integrin binding.
Proc.Natl.Acad.Sci.USA, 117, 2020
8XOL
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Cryo-EM structure of human ABCC4 with ANP bound in NBD1
分子名称: 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ATP-binding cassette sub-family C member 4, MAGNESIUM ION, ...
著者Zhang, P.F, Liu, Z.
登録日2024-01-01
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献The ATP-bound inward-open conformation of ABCC4 reveals asymmetric ATP binding for substrate transport.
Febs Lett., 2024
3F6H
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Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type III
分子名称: Alpha-isopropylmalate synthase, ISOLEUCINE, ZINC ION
著者Zhang, P, Ma, J, Zhao, G, Ding, J.
登録日2008-11-06
公開日2009-04-21
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans
Biochem.J., 421, 2009
8JES
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Cryo-EM structure of DltB homo-tetramer
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, DIACYL GLYCEROL, DODECYL-BETA-D-MALTOSIDE, ...
著者Zhang, P, Liu, Z.
登録日2023-05-16
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation.
Nat Commun, 15, 2024
8JF2
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Cryo-EM structure of tetrameric DltB/DltC complex
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, D-alanyl carrier protein, DIACYL GLYCEROL, ...
著者Zhang, P, Liu, Z.
登録日2023-05-17
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation.
Nat Commun, 15, 2024
8JEM
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DltB tetramer in complex with inhibitor m-AMSA
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, DIACYL GLYCEROL, DODECYL-BETA-D-MALTOSIDE, ...
著者Zhang, P, Liu, Z.
登録日2023-05-16
公開日2024-05-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structural insights into the transporting and catalyzing mechanism of DltB in LTA D-alanylation.
Nat Commun, 15, 2024
3TNQ
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Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein kinase, ...
著者Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
登録日2011-09-01
公開日2012-02-01
最終更新日2012-09-26
実験手法X-RAY DIFFRACTION (3.097 Å)
主引用文献Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
3TNP
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Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit
著者Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
登録日2011-09-01
公開日2012-02-01
最終更新日2013-02-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
2F5K
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Crystal structure of the chromo domain of human MRG15
分子名称: Mortality factor 4-like protein 1
著者Zhang, P, Du, J, Ding, J.
登録日2005-11-26
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3.
Nucleic Acids Res., 34, 2006
2F5J
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Crystal structure of MRG domain from human MRG15
分子名称: Mortality factor 4-like protein 1
著者Zhang, P, Du, J, Ding, J.
登録日2005-11-26
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14
Protein Sci., 15, 2006
7FHA
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Crystal structure of the ATP sulfurylase domain of human PAPSS2 in complex with APS
分子名称: ADENOSINE-5'-PHOSPHOSULFATE, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2, POTASSIUM ION, ...
著者Zhang, P, Zhang, L, Zhang, L.
登録日2021-07-29
公開日2021-12-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the substrate recognition mechanism of ATP-sulfurylase domain of human PAPS synthase 2.
Biochem.Biophys.Res.Commun., 586, 2022
7FH3
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Crystal structure of the ATP sulfurylase domain of human PAPSS2
分子名称: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2, SULFATE ION, beta-D-glucopyranose
著者Zhang, P, Zhang, L, Zhang, L.
登録日2021-07-29
公開日2021-12-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the substrate recognition mechanism of ATP-sulfurylase domain of human PAPS synthase 2.
Biochem.Biophys.Res.Commun., 586, 2022
7V1A
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Stapled TBS peptide from RIAM bound to talin R7R8 domains
分子名称: 1,2-ETHANEDIOL, ASP-ILE-ASP-GLN-MET-PHE-SER-THR-LEU-LEU-GLY-GLU-MK8-ASP-LEU-LEU-MK8-GLN-SER, Talin-1
著者Zhang, P, Gao, T, Wu, J.
登録日2022-05-11
公開日2023-06-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.845 Å)
主引用文献Inhibition of talin-induced integrin activation by a double-hit stapled peptide.
Structure, 31, 2023
3UVL
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Crystal structure of WDR5 in complex with the WDR5-interacting motif of MLL3
分子名称: Histone-lysine N-methyltransferase MLL3, WD repeat-containing protein 5
著者Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F.
登録日2011-11-30
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.
Nucleic Acids Res., 40, 2012
3URO
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Poliovirus receptor CD155 D1D2
分子名称: Poliovirus receptor
著者Zhang, P, Mueller, S, Morais, M.C, Bator, C.M, Bowman, V.D, Hafenstein, S, Wimmer, E, Rossmann, M.G.
登録日2011-11-22
公開日2011-12-07
実験手法X-RAY DIFFRACTION (3.5005 Å)
主引用文献Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses.
Proc.Natl.Acad.Sci.USA, 105, 2008
3UVO
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Crystal structure of WDR5 in complex with the WDR5-interacting motif of SET1B
分子名称: Histone-lysine N-methyltransferase SETD1B, WD repeat-containing protein 5
著者Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F.
登録日2011-11-30
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.
Nucleic Acids Res., 40, 2012
3UVN
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Crystal structure of WDR5 in complex with the WDR5-interacting motif of SET1A
分子名称: Histone-lysine N-methyltransferase SETD1A, WD repeat-containing protein 5
著者Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F.
登録日2011-11-30
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.792 Å)
主引用文献The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.
Nucleic Acids Res., 40, 2012
3UVK
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Crystal structure of WDR5 in complex with the WDR5-interacting motif of MLL2
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Histone-lysine N-methyltransferase MLL2, SULFATE ION, ...
著者Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F.
登録日2011-11-30
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.
Nucleic Acids Res., 40, 2012
3UVM
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Crystal structure of WDR5 in complex with the WDR5-interacting motif of MLL4
分子名称: Histone-lysine N-methyltransferase MLL4, WD repeat-containing protein 5
著者Zhang, P, Lee, H, Brunzelle, J.S, Couture, J.-F.
登録日2011-11-30
公開日2011-12-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.
Nucleic Acids Res., 40, 2012

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