5E2Z
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5E2Y
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5E99
| Bovine Fab fragment F08_B11 | Descriptor: | Fab F08_B11 heavy chain, Fab F08_B11 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2015-10-14 | Release date: | 2016-08-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies. Sci Immunol, 1, 2016
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5FEH
| Crystal structure of PCT64_35B, a broadly neutralizing anti-HIV antibody | Descriptor: | 1,2-ETHANEDIOL, PCT64_26 Fab heavy chain, PCT64_26 Fab light chain, ... | Authors: | Murrell, S, Wilson, I.A. | Deposit date: | 2015-12-17 | Release date: | 2017-08-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage. Immunity, 47, 2017
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5E35
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2DBL
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8V06
| Crystal structure of mouse PLD3 co-crystallized with 5'Pi-ssDNA for 9 days | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | Authors: | Yuan, M, Wilson, I.A. | Deposit date: | 2023-11-17 | Release date: | 2024-03-13 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. Structure, 32, 2024
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8V08
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8V05
| Crystal structure of mouse PLD3 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | Authors: | Yuan, M, Zhu, X, Wilson, I.A. | Deposit date: | 2023-11-17 | Release date: | 2024-03-13 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. Structure, 32, 2024
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6IEQ
| Crystal Structure of HIV-1 Env ConM SOSIP.v7 in Complex with bNAb PGT124 and 35O22 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Fab Heavy Chain, ... | Authors: | Han, B.W, Wilson, I.A. | Deposit date: | 2018-09-16 | Release date: | 2019-05-22 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence. Nat Commun, 10, 2019
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8V07
| Crystal structure of mouse PLD3 co-crystallized with 5'Pi-ssDNA for 30 days | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-3' exonuclease PLD3, ... | Authors: | Yuan, M, Wilson, I.A. | Deposit date: | 2023-11-17 | Release date: | 2024-03-13 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4. Structure, 32, 2024
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8V2E
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8VBR
| Structure of bovine anti-HIV Fab ElsE11 | Descriptor: | Bovine Fab ElsE11 light chain, Bovine Fab Else11 heavy chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Last modified: | 2024-09-25 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. Plos Pathog., 20, 2024
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8VBM
| Structure of bovine anti-HIV Fab ElsE7 | Descriptor: | Bovine Fab ElsE7 heavy chain, Bovine Fab ElsE7 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Last modified: | 2024-09-25 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. Plos Pathog., 20, 2024
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8VBK
| Structure of bovine anti-HIV Fab ElsE5 | Descriptor: | Bovine Fab ElsE5 heavy chain, Bovine Fab ElsE5 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Last modified: | 2024-09-25 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. Plos Pathog., 20, 2024
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8VBJ
| Structure of bovine anti-HIV Fab ElsE2 | Descriptor: | Bovine Fab ElsE2 heavy chain, Bovine Fab ElsE2 light chain, POTASSIUM ION, ... | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Last modified: | 2024-09-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. Plos Pathog., 20, 2024
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8VBN
| Structure of bovine anti-HIV Fab ElsE8 | Descriptor: | Bovine Fab ElsE8 heavy chain, Bovine Fab ElsE8 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Last modified: | 2024-09-25 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. Plos Pathog., 20, 2024
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8VBP
| Structure of bovine anti-HIV Fab Bess4 | Descriptor: | Bovine Fab Bess4 heavy chain, Bovine Fab Bess4 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Last modified: | 2024-09-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. Plos Pathog., 20, 2024
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8VBQ
| Structure of bovine anti-HIV Fab Bess7 | Descriptor: | Bovine Fab Bess7 heavy chain, Bovine Fab Bess7 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Last modified: | 2024-09-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. Plos Pathog., 20, 2024
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8V4I
| Structure of bovine anti-HIV Fab ElsE1 | Descriptor: | ElsE1 Fab heavy chain, ElsE1 Fab light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-11-29 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultra-long CDRH3 repertoire To Be Published
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8VBO
| Structure of bovine anti-HIV Fab ElsE9 | Descriptor: | Bovine Fab ElsE9 heavy chain, Bovine Fab ElsE9 light chain, GLYCEROL, ... | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2023-12-12 | Release date: | 2024-09-04 | Last modified: | 2024-09-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire. Plos Pathog., 20, 2024
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8VQQ
| Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule 6S | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... | Authors: | Lin, T.H, Zhu, Y, Wilson, I.A. | Deposit date: | 2024-01-19 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VQN
| Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule 6R | Descriptor: | (S~1~S,3R)-N-{3-chloro-4-[(2S)-2-phenylmorpholine-4-carbonyl]phenyl}-3-(dimethylamino)pyrrolidine-1-sulfonimidoyl fluoride, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... | Authors: | Lin, T.H, Zhu, Y, Wilson, I.A. | Deposit date: | 2024-01-18 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VQL
| Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule 6S prime | Descriptor: | (S~1~S,3S)-N-{3,5-dichloro-4-[(2S)-2-phenylmorpholine-4-carbonyl]phenyl}-3-(dimethylamino)pyrrolidine-1-sulfonimidoyl fluoride, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, T.H, Zhu, Y, Wilson, I.A. | Deposit date: | 2024-01-18 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VQM
| Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule 6R prime | Descriptor: | (S~1~S,3R)-N-{3,5-dichloro-4-[(2S)-2-phenylmorpholine-4-carbonyl]phenyl}-3-(dimethylamino)pyrrolidine-1-sulfonimidoyl fluoride, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, T.H, Zhu, Y, Wilson, I.A. | Deposit date: | 2024-01-18 | Release date: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry. Proc.Natl.Acad.Sci.USA, 121, 2024
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