6I2K
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![BU of 6i2k by Molmil](/molmil-images/mine/6i2k) | Structure of EV71 complexed with its receptor SCARB2 | Descriptor: | 1-(2-aminopyridin-4-yl)-3-[(3S)-5-{4-[(E)-(ethoxyimino)methyl]phenoxy}-3-methylpentyl]imidazolidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhou, D, Zhao, Y, Kotecha, A, Fry, E.E, Kelly, J, Wang, X, Rao, Z, Rowlands, D.J, Ren, J, Stuart, D.I. | Deposit date: | 2018-11-01 | Release date: | 2018-11-28 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2. Nat Microbiol, 4, 2019
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7JU4
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![BU of 7ju4 by Molmil](/molmil-images/mine/7ju4) | Radial spoke 2 stalk, IDAc, and N-DRC attached with doublet microtubule | Descriptor: | 28 kDa inner dynein arm light chain, axonemal, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A. | Deposit date: | 2020-08-19 | Release date: | 2020-12-16 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of radial spokes and associated complexes important for ciliary motility. Nat.Struct.Mol.Biol., 28, 2021
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7JTK
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![BU of 7jtk by Molmil](/molmil-images/mine/7jtk) | Radial spoke 1 isolated from Chlamydomonas reinhardtii | Descriptor: | Cytochrome b5 heme-binding domain-containing protein, Dynein 8 kDa light chain, flagellar outer arm, ... | Authors: | Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A. | Deposit date: | 2020-08-17 | Release date: | 2020-12-16 | Last modified: | 2021-01-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of radial spokes and associated complexes important for ciliary motility. Nat.Struct.Mol.Biol., 28, 2021
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7JTS
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![BU of 7jts by Molmil](/molmil-images/mine/7jts) | Stalk of radial spoke 1 attached with doublet microtubule from Chlamydomonas reinhardtii | Descriptor: | Calmodulin, Dynein 8 kDa light chain, flagellar outer arm, ... | Authors: | Gui, M, Ma, M, Sze-Tu, E, Wang, X, Koh, F, Zhong, E, Berger, B, Davis, J, Dutcher, S, Zhang, R, Brown, A. | Deposit date: | 2020-08-18 | Release date: | 2020-12-16 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | Structures of radial spokes and associated complexes important for ciliary motility. Nat.Struct.Mol.Biol., 28, 2021
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5ZMY
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![BU of 5zmy by Molmil](/molmil-images/mine/5zmy) | Crystal structure of a cis-epoxysuccinate hydrolase producing D(-)-tartaric acids | Descriptor: | Cis-epoxysuccinate hydrolase, D(-)-TARTARIC ACID, ZINC ION | Authors: | Dong, S, Liu, X, Wang, X, Feng, Y. | Deposit date: | 2018-04-06 | Release date: | 2018-08-08 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structural insight into the catalytic mechanism of a cis-epoxysuccinate hydrolase producing enantiomerically pure d(-)-tartaric acid. Chem. Commun. (Camb.), 54, 2018
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6JHR
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![BU of 6jhr by Molmil](/molmil-images/mine/6jhr) | The cryo-EM structure of HAV bound to a neutralizing antibody-F6 | Descriptor: | FAB Heavy Chain, FAB Light Chain, VP1, ... | Authors: | Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X. | Deposit date: | 2019-02-18 | Release date: | 2020-03-18 | Method: | ELECTRON MICROSCOPY (3.68 Å) | Cite: | Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors. Plos Biol., 17, 2019
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6J11
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![BU of 6j11 by Molmil](/molmil-images/mine/6j11) | MERS-CoV spike N-terminal domain and 7D10 scFv complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-terminal domain of Spike glycoprotein, ... | Authors: | Zhou, H, Zhang, S, Zhang, S, Tang, W, Wang, X. | Deposit date: | 2018-12-27 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein. Nat Commun, 10, 2019
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6JHT
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![BU of 6jht by Molmil](/molmil-images/mine/6jht) | The cryo-EM structure of HAV bound to a neutralizing antibody-F9 | Descriptor: | FAB Heavy Chain, FAB Light Chain, VP1, ... | Authors: | Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X. | Deposit date: | 2019-02-19 | Release date: | 2020-03-18 | Method: | ELECTRON MICROSCOPY (3.79 Å) | Cite: | Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors. Plos Biol., 17, 2019
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6JHQ
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![BU of 6jhq by Molmil](/molmil-images/mine/6jhq) | The cryo-EM structure of HAV bound to a neutralizing antibody-F4 | Descriptor: | FAB Heavy Chain, FAB Light Chain, VP1, ... | Authors: | Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X. | Deposit date: | 2019-02-18 | Release date: | 2020-03-18 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors. Plos Biol., 17, 2019
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8IFG
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![BU of 8ifg by Molmil](/molmil-images/mine/8ifg) | Cryo-EM structure of the Clr6S (Clr6-HDAC) complex from S. pombe | Descriptor: | Chromatin modification-related protein eaf3, Cph1, Cph2, ... | Authors: | Zhang, H.Q, Wang, X, Wang, Y.N, Liu, S.M, Zhang, Y, Xu, K, Ji, L.T, Kornberg, R.D. | Deposit date: | 2023-02-17 | Release date: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Class I histone deacetylase complex: Structure and functional correlates. Proc Natl Acad Sci U S A, 120, 2023
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7CWM
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![BU of 7cwm by Molmil](/molmil-images/mine/7cwm) | |
7CWN
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![BU of 7cwn by Molmil](/molmil-images/mine/7cwn) | P17-H014 Fab cocktail in complex with SARS-CoV-2 spike protein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Wang, N, Wang, X. | Deposit date: | 2020-08-29 | Release date: | 2020-12-16 | Last modified: | 2021-01-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection. Cell Res., 31, 2021
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8GNA
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![BU of 8gna by Molmil](/molmil-images/mine/8gna) | Structure of the SbCas7-11-crRNA-NTR complex | Descriptor: | RAMP superfamily protein, RNA (32-MER), RNA (5'-R(P*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*GP*U)-3'), ... | Authors: | Yu, G, Wang, X, Deng, Z, Zhang, H. | Deposit date: | 2022-08-23 | Release date: | 2023-01-18 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Target RNA-guided protease activity in type III-E CRISPR-Cas system. Nucleic Acids Res., 50, 2022
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8GU6
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![BU of 8gu6 by Molmil](/molmil-images/mine/8gu6) | Structure of the SbCas7-11-crRNA-NTR-Csx29 complex | Descriptor: | CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... | Authors: | Yu, G, Wang, X, Deng, Z, Zhang, H. | Deposit date: | 2022-09-10 | Release date: | 2023-01-18 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Target RNA-guided protease activity in type III-E CRISPR-Cas system. Nucleic Acids Res., 50, 2022
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7E5R
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![BU of 7e5r by Molmil](/molmil-images/mine/7e5r) | SARS-CoV-2 S trimer with three-antibody cocktail complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FC05 heavy chain, FC05 light chain, ... | Authors: | Sun, Y, Wang, L, Wang, N, Feng, R, Wang, X. | Deposit date: | 2021-02-20 | Release date: | 2021-10-13 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms. Cell Res., 31, 2021
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7E5S
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![BU of 7e5s by Molmil](/molmil-images/mine/7e5s) | SARS-CoV-2 S trimer with four-antibody cocktail complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FC05 heavy chain, FC05 light chain, ... | Authors: | Sun, Y, Wang, L, Wang, N, Feng, R, Wang, X. | Deposit date: | 2021-02-20 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms. Cell Res., 31, 2021
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7WG6
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![BU of 7wg6 by Molmil](/molmil-images/mine/7wg6) | Neutral Omicron Spike Trimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Cui, Z, Wang, X. | Deposit date: | 2021-12-28 | Release date: | 2022-05-18 | Last modified: | 2022-07-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron. Cell, 185, 2022
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8A2F
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![BU of 8a2f by Molmil](/molmil-images/mine/8a2f) | Crystal Structure of Ljunganvirus 1 2A protein | Descriptor: | 2A protein | Authors: | von Castelmur, E, Zhu, L, Wang, X, Fry, E, Ren, J, Perrakis, A, Stuart, D.I. | Deposit date: | 2022-06-03 | Release date: | 2023-06-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Structural plasticity of 2A proteins in the Parechovirus family To Be Published
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8A2E
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![BU of 8a2e by Molmil](/molmil-images/mine/8a2e) | Crystal Structure of Human Parechovirus 3 2A protein | Descriptor: | 2A protein, GLYCEROL, SULFATE ION | Authors: | von Castelmur, E, Zhu, L, wang, X, Fry, E, Ren, J, Perrakis, A, Stuart, D.I. | Deposit date: | 2022-06-03 | Release date: | 2023-06-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structural plasticity of 2A proteins in the Parechovirus family. To Be Published
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7EVM
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![BU of 7evm by Molmil](/molmil-images/mine/7evm) | Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex | Descriptor: | CHOLESTEROL, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Cong, Z, Chen, L, Ma, H, Zhou, Q, Zou, X, Ye, C, Dai, A, Liu, Q, Huang, W, Sun, X, Wang, X, Xu, P, Zhao, L, Xia, T, Zhong, W, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | Deposit date: | 2021-05-21 | Release date: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor. Nat Commun, 12, 2021
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2NC5
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![BU of 2nc5 by Molmil](/molmil-images/mine/2nc5) | Solution Structure of N-Xylosylated Pin1 WW Domain | Descriptor: | Pin1 WW Domain, beta-D-xylopyranose | Authors: | Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W. | Deposit date: | 2016-03-20 | Release date: | 2016-06-08 | Last modified: | 2020-07-29 | Method: | SOLUTION NMR | Cite: | The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate. J.Am.Chem.Soc., 138, 2016
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2NC3
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![BU of 2nc3 by Molmil](/molmil-images/mine/2nc3) | Solution Structure of N-Allosylated Pin1 WW Domain | Descriptor: | Pin1 WW Domain, beta-D-allopyranose | Authors: | Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W. | Deposit date: | 2016-03-20 | Release date: | 2016-06-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate. J.Am.Chem.Soc., 138, 2016
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7DUQ
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![BU of 7duq by Molmil](/molmil-images/mine/7duq) | Cryo-EM structure of the compound 2 and GLP-1-bound human GLP-1 receptor-Gs complex | Descriptor: | CHOLESTEROL, Glucagon-like peptide 1, Glucagon-like peptide 1 receptor, ... | Authors: | Cong, Z, Chen, L, Ma, H, Zhou, Q, Zou, X, Ye, C, Dai, A, Liu, Q, Huang, W, Sun, X, Wang, X, Xu, P, Zhao, L, Xia, T, Zhong, W, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | Deposit date: | 2021-01-11 | Release date: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor. Nat Commun, 12, 2021
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7DUR
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![BU of 7dur by Molmil](/molmil-images/mine/7dur) | Cryo-EM structure of the compound 2-bound human GLP-1 receptor-Gs complex | Descriptor: | CHOLESTEROL, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Cong, Z, Chen, L, Ma, H, Zhou, Q, Zou, X, Ye, C, Dai, A, Liu, Q, Huang, W, Sun, X, Wang, X, Xu, P, Zhao, L, Xia, T, Zhong, W, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | Deposit date: | 2021-01-11 | Release date: | 2021-08-11 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor. Nat Commun, 12, 2021
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7F3Q
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![BU of 7f3q by Molmil](/molmil-images/mine/7f3q) | SARS-CoV-2 RBD in complex with A5-10 Fab and A34-2 Fab | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of A34-2 Fab, ... | Authors: | Dou, Y, Wang, X, Liu, P, Lu, B, Wang, K. | Deposit date: | 2021-06-16 | Release date: | 2022-06-22 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Development of neutralizing antibodies against SARS-CoV-2, using a high-throughput single-B-cell cloning method. Antib Ther, 6, 2023
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