3C4E
 
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3ET2
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3ET0
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3RO3
 | | crystal structure of LGN/mInscuteable complex | | 分子名称: | CHLORIDE ION, ETHANOL, G-protein-signaling modulator 2, ... | | 著者 | Zhu, J, Wen, W, Shang, Y, Wei, Z, Pan, Z, Wang, W, Zhang, M. | | 登録日 | 2011-04-25 | | 公開日 | 2012-03-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G[alpha]i/LGN/NuMA pathways
Mol.Cell, 43, 2011
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3C4C
 | | B-Raf Kinase in Complex with PLX4720 | | 分子名称: | B-Raf proto-oncogene serine/threonine-protein kinase, N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide | | 著者 | Zhang, K.Y.J, Wang, W. | | 登録日 | 2008-01-29 | | 公開日 | 2008-02-26 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3ET3
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3ET1
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4FXX
 | | Structure of SF1 coiled-coil domain | | 分子名称: | IMIDAZOLE, MALONATE ION, Splicing factor 1 | | 著者 | Gupta, A, Bauer, W.J, Wang, W, Kielkopf, C.L. | | 登録日 | 2012-07-03 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4801 Å) | | 主引用文献 | Structure of Phosphorylated SF1 Bound to U2AF(65) in an Essential Splicing Factor Complex.
Structure, 21, 2013
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4G2V
 | | Structure complex of LGN binding with FRMPD1 | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, G-protein-signaling modulator 2, ... | | 著者 | Shang, Y, Pan, Z, Wen, W, Wang, W, Zhang, M. | | 登録日 | 2012-07-13 | | 公開日 | 2013-01-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and biochemical characterization of the interaction between LGN and Frmpd1
J.Mol.Biol., 425, 2013
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4G5R
 | | Structure of LGN GL4/Galphai3 complex | | 分子名称: | CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W. | | 登録日 | 2012-07-18 | | 公開日 | 2012-09-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.481 Å) | | 主引用文献 | Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
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4FSH
 | | Crystal Structure of Shikimate Dehydrogenase (aroE) Clinical Variant v2356 from Helicobacter pylori in Complex with Shikimate | | 分子名称: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, Shikimate dehydrogenase | | 著者 | Cheng, W.C, Chen, T.J, Wang, W.C. | | 登録日 | 2012-06-27 | | 公開日 | 2013-01-30 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystal Structure of Shikimate Dehydrogenase (aroE) Clinical Variant v2356 from Helicobacter pylori in Complex with Shikimate
TO BE PUBLISHED
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7K0V
 | | Crystal structure of bRaf in complex with inhibitor GNE-0749 | | 分子名称: | CHLORIDE ION, N-(3,3-dimethylbutyl)-N'-{2-fluoro-5-[(5-fluoro-3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]-4-methylphenyl}urea, Non-specific serine/threonine protein kinase | | 著者 | Yin, J, Eigenbrot, C.E, Wang, W. | | 登録日 | 2020-09-06 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5-Fluoro-4-(3 H )-quinazolinone Aryl Urea pan-RAF Kinase Inhibitor.
J.Med.Chem., 64, 2021
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4HO5
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4HO3
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4HO6
 | | Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-glucose and UTP | | 分子名称: | Glucose-1-phosphate thymidylyltransferase, SULFATE ION, URIDINE 5'-TRIPHOSPHATE, ... | | 著者 | Chen, T.J, Chien, W.T, Lin, C.C, Wang, W.C. | | 登録日 | 2012-10-22 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-glucose and UTP
TO BE PUBLISHED
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4HOC
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4HO2
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4HO0
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4HO4
 | | Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with thymidine and glucose-1-phosphate | | 分子名称: | 1-O-phosphono-alpha-D-glucopyranose, Glucose-1-phosphate thymidylyltransferase, SULFATE ION, ... | | 著者 | Chen, T.J, Chien, W.T, Lin, C.C, Wang, W.C. | | 登録日 | 2012-10-22 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with thymidine and glucose-1-phosphate
TO BE PUBLISHED
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4HO9
 | | Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-galactose and UTP | | 分子名称: | GALACTOSE-URIDINE-5'-DIPHOSPHATE, Glucose-1-phosphate thymidylyltransferase, SULFATE ION, ... | | 著者 | Chen, T.J, Chien, W.T, Lin, C.C, Wang, W.C. | | 登録日 | 2012-10-22 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-galactose and UTP
TO BE PUBLISHED
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7WD4
 | | Crystal structure of the Ilheus virus helicase: implications for enzyme function and drug design | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, NS3 helicase | | 著者 | Wang, D.P, Wang, M.Y, Zhou, X, Wang, W.M, Cao, J.M. | | 登録日 | 2021-12-21 | | 公開日 | 2023-01-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of the Ilheus virus helicase: implications for enzyme function and drug design
To Be Published
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8IWH
 | | Structure and characteristics of a photosystem II supercomplex containing monomeric LHCX and dimeric FCPII antennae from the diatom Thalassiosira pseudonana | | 分子名称: | (1~{R})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15-octaen-17-ynyl]cyclohex-3-en-1-ol, (3S,3'R,5R,6S,7cis)-7',8'-didehydro-5,6-dihydro-5,6-epoxy-beta,beta-carotene-3,3'-diol, (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate, ... | | 著者 | Feng, Y, Li, Z.H, Wang, W.D, Shen, J.R. | | 登録日 | 2023-03-30 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | | 主引用文献 | Structure of a diatom photosystem II supercomplex containing a member of Lhcx family and dimeric FCPII.
Sci Adv, 9, 2023
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5GTB
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7V4Y
 | | TTHA1264/TTHA1265 complex | | 分子名称: | Putative zinc protease, ZINC ION, Zinc-dependent peptidase | | 著者 | Xu, M, Xu, Q, Ran, T, Wang, W, Sun, B, Wang, Q. | | 登録日 | 2021-08-16 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of TTHA1265 and TTHA1264/TTHA1265 complex reveal an intrinsic heterodimeric assembly.
Int.J.Biol.Macromol., 207, 2022
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4L4M
 | | Structural Analysis of a Phosphoribosylated Inhibitor in Complex with Human Nicotinamide Phosphoribosyltransferase | | 分子名称: | 1,2-ETHANEDIOL, N-{4-[(3,5-difluorophenyl)sulfonyl]benzyl}imidazo[1,2-a]pyridine-7-carboxamide, Nicotinamide phosphoribosyltransferase, ... | | 著者 | Oh, A, Ho, Y, Zak, M, Liu, Y, Yuen, P, Zheng, X, Dragovich, S.P, Wang, W. | | 登録日 | 2013-06-08 | | 公開日 | 2014-06-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.445 Å) | | 主引用文献 | Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase.
Chembiochem, 15, 2014
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