7Z0J
 
 | | human PEX13 SH3 domain in complex with internal FxxxF motif | | Descriptor: | 1,2-ETHANEDIOL, Peroxisomal membrane protein PEX13 | | Authors: | Gaussmann, S, Zak, K, Kreisz, N, Sattler, M. | | Deposit date: | 2022-02-23 | | Release date: | 2023-03-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Intramolecular autoinhibition of human PEX13 modulates peroxisomal import
Biorxiv, 2022
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7Z0K
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7Z0I
 | | human PEX13 SH3 domain | | Descriptor: | 1,2-ETHANEDIOL, Peroxisomal membrane protein PEX13, ZINC ION | | Authors: | Gaussmann, S, Zak, K, Sattler, M. | | Deposit date: | 2022-02-23 | | Release date: | 2023-03-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Intramolecular autoinhibition of human PEX13 modulates peroxisomal import
Biorxiv, 2022
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5AGQ
 | | Solution structure of the TAM domain of human TIP5 BAZ2A involved in epigenetic regulation of rRNA genes | | Descriptor: | BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2A | | Authors: | Anosova, I, Melnik, S, Tripsianes, K, Kateb, F, Grummt, I, Sattler, M. | | Deposit date: | 2015-02-03 | | Release date: | 2015-05-06 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | A Novel RNA Binding Surface of the Tam Domain of Tip5/Baz2A Mediates Epigenetic Regulation of Rrna Genes.
Nucleic Acids Res., 43, 2015
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2JW6
 | | Solution structure of the DEAF1 MYND domain | | Descriptor: | Deformed epidermal autoregulatory factor 1 homolog, ZINC ION | | Authors: | Spadaccini, R, Perrin, H, Bottomley, M, Ansieu, S, Sattler, M. | | Deposit date: | 2007-10-08 | | Release date: | 2007-12-25 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Retraction notice to "Structure and functional analysis of the MYND domain" [J. Mol. Biol. (2006) 358, 498-508].
J.Mol.Biol., 376, 2008
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1T2R
 | | Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | | Descriptor: | 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2 | | Authors: | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | | Deposit date: | 2004-04-22 | | Release date: | 2004-06-01 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
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1T2S
 | | Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | | Descriptor: | 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2 | | Authors: | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | | Deposit date: | 2004-04-22 | | Release date: | 2004-06-01 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
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5L87
 | | Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases. | | Descriptor: | 1,2-ETHANEDIOL, 5-(1~{H}-indol-3-ylmethyl)-1-methyl-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide, Peroxin 14 | | Authors: | Dawidowski, M, Emmanouilidis, L, Sattler, M, Popowicz, G.M. | | Deposit date: | 2016-06-07 | | Release date: | 2017-03-08 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (0.87 Å) | | Cite: | Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.
Science, 355, 2017
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5L8A
 | | Targeting the PEX14-PEX5 interaction by small molecules provides novel therapeutic routes to treat trypanosomiases. | | Descriptor: | 1,2-ETHANEDIOL, 1-(2-hydroxyethyl)-5-[(4-methoxynaphthalen-1-yl)methyl]-~{N}-(phenylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide, GLYCINE, ... | | Authors: | Dawidowski, M, Emmanouilidis, L, Sattler, M, Popowicz, G.M. | | Deposit date: | 2016-06-07 | | Release date: | 2017-03-08 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.57 Å) | | Cite: | Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.
Science, 355, 2017
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1SHC
 | | SHC PTB DOMAIN COMPLEXED WITH A TRKA RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | SHC, TRKA RECEPTOR PHOSPHOPEPTIDE | | Authors: | Zhou, M.-M, Ravichandran, K.S, Olejniczak, E.T, Petros, A.M, Meadows, R.P, Sattler, M, Harlan, J.E, Wade, W.S, Burakoff, S.J, Fesik, S.W. | | Deposit date: | 1996-03-27 | | Release date: | 1997-05-15 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Structure and ligand recognition of the phosphotyrosine binding domain of Shc.
Nature, 378, 1995
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7AAF
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7AAO
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3ZYH
 | | CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALBG0 AT 1.5 A RESOLUTION | | Descriptor: | 3-(beta-D-galactopyranosylthio)propanoic acid, CALCIUM ION, PA-I galactophilic lectin | | Authors: | Kadam, R.U, Bergmann, M, Hurley, M, Garg, D, Cacciarini, M, Swiderska, M.A, Nativi, C, Sattler, M, Smyth, A.R, Williams, P, Camara, M, Stocker, A, Darbre, T, Reymond, J.-L. | | Deposit date: | 2011-08-23 | | Release date: | 2011-09-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.501 Å) | | Cite: | A Glycopeptide Dendrimer Inhibitor of the Galactose Specific Lectin Leca and of Pseudomonas Aeruginosa Biofilms
Angew.Chem.Int.Ed.Engl., 50, 2011
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3ZYB
 | | CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH GALAG0 AT 2.3 A RESOLUTION | | Descriptor: | CALCIUM ION, GALA-LYS-PRO-LEUNH2, P-HYDROXYBENZOIC ACID, ... | | Authors: | Kadam, R.U, Bergmann, M, Hurley, M, Garg, D, Cacciarini, M, Swiderska, M.A, Nativi, C, Sattler, M, Smyth, A.R, Williams, P, Camara, M, Stocker, A, Darbre, T, Reymond, J.-L. | | Deposit date: | 2011-08-19 | | Release date: | 2011-09-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | A Glycopeptide Dendrimer Inhibitor of the Galactose-Specific Lectin Leca and of Pseudomonas Aeruginosa Biofilms.
Angew.Chem.Int.Ed.Engl., 50, 2011
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3ZYF
 | | CRYSTAL STRUCTURE OF PA-IL LECTIN COMPLEXED WITH NPG AT 1.9 A RESOLUTION | | Descriptor: | 4-nitrophenyl beta-D-galactopyranoside, CALCIUM ION, PA-I GALACTOPHILIC LECTIN | | Authors: | Kadam, R.U, Bergmann, M, Hurley, M, Garg, D, Cacciarini, M, Swiderska, M.A, Nativi, C, Sattler, M, Smyth, A.R, Williams, P, Camara, M, Stocker, A, Darbre, T, Reymond, J.-L. | | Deposit date: | 2011-08-22 | | Release date: | 2011-09-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.944 Å) | | Cite: | A Glycopeptide Dendrimer Inhibitor of the Galactose-Specific Lectin Leca and of Pseudomonas Aeruginosa Biofilms.
Angew.Chem.Int.Ed.Engl., 50, 2011
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2JXC
 | | Structure of the EPS15-EH2 Stonin2 Complex | | Descriptor: | CALCIUM ION, Epidermal growth factor receptor substrate 15, Stonin-2 | | Authors: | Rumpf, J, Simon, B, Jung, N, Maritzen, T, Haucke, V, Sattler, M, Groemping, Y. | | Deposit date: | 2007-11-12 | | Release date: | 2008-01-08 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure of the Eps15-stonin2 complex provides a molecular explanation for EH-domain ligand specificity.
Embo J., 27, 2008
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4Q9B
 | | IgNAR antibody domain C2 | | Descriptor: | Novel antigen receptor | | Authors: | Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J. | | Deposit date: | 2014-04-30 | | Release date: | 2014-07-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4Q9C
 | | IgNAR antibody domain C3 | | Descriptor: | CHLORIDE ION, Novel antigen receptor, SODIUM ION, ... | | Authors: | Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J. | | Deposit date: | 2014-04-30 | | Release date: | 2014-07-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4Q97
 | | IgNAR antibody domain C1 | | Descriptor: | Novel antigen receptor | | Authors: | Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J. | | Deposit date: | 2014-04-29 | | Release date: | 2014-07-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
Proc.Natl.Acad.Sci.USA, 111, 2014
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1KKS
 | | Structure of the histone mRNA hairpin required for cell cycle regulation of histone gene expression | | Descriptor: | 5'-R(*GP*GP*AP*AP*GP*GP*CP*CP*CP*UP*UP*UP*UP*CP*AP*GP*GP*GP*CP*CP*AP*CP*CP*C)-3' | | Authors: | Zanier, K, Luyten, I, Crombie, C, Muller, B, Schuemperli, D, Linge, J.P, Nilges, M, Sattler, M. | | Deposit date: | 2001-12-10 | | Release date: | 2002-03-13 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure of the histone mRNA hairpin required for cell cycle regulation of histone gene expression.
RNA, 8, 2002
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3NC0
 | | Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal II) | | Descriptor: | DI(HYDROXYETHYL)ETHER, Exportin-1, GLYCEROL, ... | | Authors: | Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. | | Deposit date: | 2010-06-04 | | Release date: | 2010-10-27 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
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3NBY
 | | Crystal structure of the PKI NES-CRM1-RanGTP nuclear export complex | | Descriptor: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. | | Deposit date: | 2010-06-04 | | Release date: | 2010-10-27 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.42 Å) | | Cite: | NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
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3NBZ
 | | Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal I) | | Descriptor: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. | | Deposit date: | 2010-06-04 | | Release date: | 2010-10-27 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
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3NC1
 | | Crystal structure of the CRM1-RanGTP complex | | Descriptor: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. | | Deposit date: | 2010-06-04 | | Release date: | 2010-10-27 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
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1K1G
 | | STRUCTURAL BASIS FOR RECOGNITION OF THE INTRON BRANCH SITE RNA BY SPLICING FACTOR 1 | | Descriptor: | 5'-R(*UP*AP*UP*AP*CP*UP*AP*AP*CP*AP*A)-3', SF1-Bo isoform | | Authors: | Liu, Z, Luyten, I, Bottomley, M.J, Messias, A.C, Houngninou-Molango, S, Sprangers, R, Zanier, K, Kramer, A, Sattler, M. | | Deposit date: | 2001-09-25 | | Release date: | 2001-11-07 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structural basis for recognition of the intron branch site RNA by splicing factor 1.
Science, 294, 2001
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