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PDB: 151 results

6F8F
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BU of 6f8f by Molmil
Co-crystal structure of SPOP MATH domain and human Pdx1 fragment
Descriptor: Pancreas/duodenum homeobox protein 1, Speckle-type POZ protein
Authors:Ostertag, M.S, Popowicz, G.M, Sattler, M.
Deposit date:2017-12-13
Release date:2018-11-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation.
Structure, 27, 2019
4A4G
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BU of 4a4g by Molmil
Solution structure of SMN Tudor domain in complex with asymmetrically dimethylated arginine
Descriptor: NG,NG-DIMETHYL-L-ARGININE, SURVIVAL MOTOR NEURON PROTEIN
Authors:Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M.
Deposit date:2011-10-12
Release date:2011-11-30
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins
Nat.Struct.Mol.Biol., 18, 2011
4A24
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BU of 4a24 by Molmil
Structural and functional analysis of the DEAF-1 and BS69 MYND domains
Descriptor: DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG, ZINC ION
Authors:Kateb, F, Perrin, H, Tripsianes, K, Zou, P, Spadaccini, R, Bottomley, M, Bepperling, A, Ansieau, S, Sattler, M.
Deposit date:2011-09-22
Release date:2012-11-07
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural and Functional Analysis of the Deaf-1 and Bs69 Mynd Domains.
Plos One, 8, 2013
4A4F
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Solution structure of SPF30 Tudor domain in complex with symmetrically dimethylated arginine
Descriptor: N3, N4-DIMETHYLARGININE, SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30
Authors:Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M.
Deposit date:2011-10-12
Release date:2011-11-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins
Nat.Struct.Mol.Biol., 18, 2011
4A4E
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BU of 4a4e by Molmil
Solution structure of SMN Tudor domain in complex with symmetrically dimethylated arginine
Descriptor: N3, N4-DIMETHYLARGININE, SURVIVAL MOTOR NEURON PROTEIN
Authors:Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M.
Deposit date:2011-10-12
Release date:2011-11-30
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins
Nat.Struct.Mol.Biol., 18, 2011
4A4H
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BU of 4a4h by Molmil
Solution structure of SPF30 Tudor domain in complex with asymmetrically dimethylated arginine
Descriptor: NG,NG-DIMETHYL-L-ARGININE, SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30
Authors:Tripsianes, K, Madl, T, Machyna, M, Fessas, D, Englbrecht, C, Fischer, U, Neugebauer, K.M, Sattler, M.
Deposit date:2011-10-12
Release date:2011-11-30
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structural Basis for Dimethyl-Arginine Recognition by the Tudor Domains of Human Smn and Spf30 Proteins
Nat.Struct.Mol.Biol., 18, 2011
6I41
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BU of 6i41 by Molmil
Co-crystal structure of human SPOP MATH domain (wild-type) and human BRD3 fragment
Descriptor: Bromodomain-containing protein 3, Speckle-type POZ protein
Authors:Ostertag, M.S, Popowicz, G.M, Sattler, M.
Deposit date:2018-11-08
Release date:2019-05-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
6I5P
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BU of 6i5p by Molmil
Co-crystal structure of human SPOP MATH domain (E47K) and human BRD3 fragment
Descriptor: Bromodomain-containing protein 3, Speckle-type POZ protein
Authors:Ostertag, M.S, Popowicz, G.M, Sattler, M.
Deposit date:2018-11-14
Release date:2019-05-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
6I7A
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BU of 6i7a by Molmil
Co-crystal structure of human SPOP MATH domain (D140N) and human BRD3 fragment
Descriptor: Bromodomain-containing protein 3, Speckle-type POZ protein
Authors:Ostertag, M.S, Popowicz, G.M, Sattler, M.
Deposit date:2018-11-16
Release date:2019-05-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
6I68
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BU of 6i68 by Molmil
Co-crystal structure of human SPOP MATH domain (M117V) and human BRD3 fragment
Descriptor: Bromodomain-containing protein 3, Speckle-type POZ protein
Authors:Ostertag, M.S, Popowicz, G.M, Sattler, M.
Deposit date:2018-11-15
Release date:2019-05-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
6TR0
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BU of 6tr0 by Molmil
Solution structure of U2AF2 RRM1,2
Descriptor: Splicing factor U2AF 65 kDa subunit
Authors:Kang, H.-S, Sattler, M.
Deposit date:2019-12-17
Release date:2020-05-06
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2.
Proc.Natl.Acad.Sci.USA, 117, 2020
6SLO
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BU of 6slo by Molmil
Crystal structure of PUF60 UHM domain in complex with 7,8 dimethoxyperphenazine
Descriptor: 2-[4-[3-(8-chloranyl-2,3-dimethoxy-phenothiazin-10-yl)propyl]piperazin-1-yl]ethanol, MAGNESIUM ION, Thioredoxin,Poly(U)-binding-splicing factor PUF60
Authors:Jagtap, P.K.A, Kubelka, T, Bach, T, Sattler, M.
Deposit date:2019-08-20
Release date:2020-09-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly.
Nat Commun, 11, 2020
6YI4
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BU of 6yi4 by Molmil
Structure of IMP-13 metallo-beta-lactamase complexed with citrate anion
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, BETA-MERCAPTOETHANOL, ...
Authors:Zak, K.M, Zhou, R.X, Softley, C.A, Bostock, M.J, Sattler, M, Popowicz, G.M.
Deposit date:2020-03-31
Release date:2020-04-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of IMP-13 metallo-beta-lactamase complexed with citrate anion
Not published
6ZFW
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BU of 6zfw by Molmil
X-ray structure of the soluble N-terminal domain of T. cruzi PEX-14
Descriptor: ACETATE ION, BETA-MERCAPTOETHANOL, GLYCEROL, ...
Authors:Softley, C.A, Ostertag, M.O, Sattler, M, Popowicz, G.P.
Deposit date:2020-06-18
Release date:2020-12-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Deep learning model predicts water interaction sites on the surface of proteins using limited-resolution data.
Chem.Commun.(Camb.), 56, 2020
2WAC
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BU of 2wac by Molmil
Extended Tudor domain of Drosophila Melanogaster Tudor-SN (p100)
Descriptor: CG7008-PA
Authors:Friberg, A, Corsini, L, Sattler, M.
Deposit date:2009-02-04
Release date:2009-03-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and Ligand Binding of the Extended Tudor Domain of D. Melanogaster Tudor-Sn
J.Mol.Biol., 387, 2009
2W4S
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BU of 2w4s by Molmil
novel RNA-binding domain in Cryptosporidium parvum at 2.5 angstrom resolution
Descriptor: Ankyrin-repeat protein
Authors:Varrot, A, Mackereth, C, Mourao, A, Sattler, M, Cusack, S.
Deposit date:2008-12-02
Release date:2009-12-29
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax.
RNA, 16, 2010
2XC7
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BU of 2xc7 by Molmil
Solution Structure of PHAX-RBD in complex with ssRNA
Descriptor: 5'-(AP*UP*CP*GP)-3', PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN
Authors:Mourao, A, Mackereth, C.D, Varrot, A, Cusack, S, Sattler, M.
Deposit date:2010-04-18
Release date:2010-04-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax.
RNA, 16, 2010
2XL1
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BU of 2xl1 by Molmil
Structural basis of translational stalling by human cytomegalovirus (hCMV) and fungal arginine attenuator peptide (AAP)
Descriptor: ARGININE ATTENUATOR PEPTIDE
Authors:Meyer, N.H, Sattler, M.
Deposit date:2010-07-15
Release date:2010-10-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis for Translational Stalling by Human Cytomegalovirus and Fungal Arginine Attenuator Peptide.
Mol.Cell, 40, 2010
5LSO
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BU of 5lso by Molmil
Crystal structure of SPF45 UHM domain with cyclic peptide inhibitor
Descriptor: LYS-SER-ARG-TRP-ASP-GLU, Splicing factor 45
Authors:Jagtap, P.K.A, Garg, D, Sattler, M.
Deposit date:2016-09-05
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing.
J. Med. Chem., 59, 2016
5MF9
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BU of 5mf9 by Molmil
Solution structure of the RBM5 OCRE domain in complex with polyproline SmN peptide.
Descriptor: RNA-binding protein 5, Survival motor neuron protein
Authors:Mourao, A, Sattler, M, Bonnal, S, Komal, S, Warner, L, Bordonne, R, Valcarcel, J.
Deposit date:2016-11-17
Release date:2016-12-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural basis for the recognition ofspliceosomal SmN B B proteins by theRBM5 OCRE domain in splicing regulation
Elife, 5, 2016
5MFY
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BU of 5mfy by Molmil
RBM5 OCRE domain
Descriptor: RNA-binding protein 5
Authors:Warner, L.R, Mourao, A, Soni, K, Sattler, M.
Deposit date:2016-11-19
Release date:2016-12-07
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulation.
Elife, 5, 2016
2L8D
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BU of 2l8d by Molmil
Structure/function of the LBR Tudor domain
Descriptor: Lamin-B receptor
Authors:Liokatis, S, Edlich, C, Soupsana, K, Giannios, I, Sattler, M, Georgatos, S.D, Politou, A.S.
Deposit date:2011-01-10
Release date:2011-11-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure and molecular interactions of lamin B receptor tudor domain.
J.Biol.Chem., 287, 2012
2M0G
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BU of 2m0g by Molmil
Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition
Descriptor: Splicing factor 1, Splicing factor U2AF 65 kDa subunit
Authors:Madl, T, Sattler, M, Zhang, Y, Bagdiul, I, Kern, T, Kang, H, Zou, P, Maeusbacher, N, Sieber, S.A, Kraemer, A.
Deposit date:2012-10-25
Release date:2013-01-30
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition.
Nucleic Acids Res., 41, 2013
2M09
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BU of 2m09 by Molmil
Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition
Descriptor: Splicing factor 1
Authors:Madl, T, Sattler, M, Zhang, Y, Bagdiul, I, Kern, T, Kang, H, Zou, P, Maeusbacher, N, Sieber, S.A, Kraemer, A.
Deposit date:2012-10-22
Release date:2013-01-30
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition.
Nucleic Acids Res., 41, 2013
2N2J
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BU of 2n2j by Molmil
Solution structure of the EBNA-2 N-terminal Dimerization (END) domain from the Epstein-barr virus
Descriptor: Epstein-Barr nuclear antigen 2
Authors:Friberg, A, Sattler, M.
Deposit date:2015-05-09
Release date:2015-06-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The EBNA-2 N-Terminal Transactivation Domain Folds into a Dimeric Structure Required for Target Gene Activation.
Plos Pathog., 11, 2015

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