1BXL
 
 | | STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | BAK PEPTIDE, BCL-XL | | Authors: | Sattler, M, Liang, H, Nettesheim, D, Meadows, R.P, Harlan, J.E, Eberstadt, M, Yoon, H, Shuker, S.B, Chang, B.S, Minn, A.J, Thompson, C.B, Fesik, S.W. | | Deposit date: | 1996-10-16 | | Release date: | 1997-10-29 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis.
Science, 275, 1997
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2MJN
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5LNF
 | | Solution NMR structure of farnesylated PEX19, C-terminal domain | | Descriptor: | FARNESYL, Peroxisomal biogenesis factor 19 | | Authors: | Emmanouilidis, L, Schuetz, U, Tripsianes, K, Madl, T, Radke, J, Rucktaeschel, R, Wilmanns, M, Schliebs, W, Erdmann, R, Sattler, M. | | Deposit date: | 2016-08-04 | | Release date: | 2017-03-15 | | Last modified: | 2019-09-11 | | Method: | SOLUTION NMR | | Cite: | Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19.
Nat Commun, 8, 2017
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6DCL
 | | Crystal structure of UP1 bound to pri-miRNA-18a terminal loop | | Descriptor: | 1,2-ETHANEDIOL, Heterogeneous nuclear ribonucleoprotein A1, RNA (5'-R(*AP*GP*UP*AP*GP*AP*UP*UP*AP*GP*C)-3') | | Authors: | Kooshapur, H, Sattler, M. | | Deposit date: | 2018-05-07 | | Release date: | 2018-06-27 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.497 Å) | | Cite: | Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1.
Nat Commun, 9, 2018
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9GAG
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4UQT
 | | RRM-peptide structure in RES complex | | Descriptor: | PRE-MRNA-SPLICING FACTOR CWC26, U2 SNRNP COMPONENT IST3 | | Authors: | Tripsianes, K, Friberg, A, Barrandon, C, Seraphin, B, Sattler, M. | | Deposit date: | 2014-06-25 | | Release date: | 2014-09-03 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | A Novel Protein-Protein Interaction in the Res (Retention and Splicing) Complex.
J.Biol.Chem., 289, 2014
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6R8G
 | | Crystal structure of malate dehydrogenase from Plasmodium Falciparum in complex with 4-(3,4-difluorophenyl)thiazol-2-amine | | Descriptor: | 4-[3,4-bis(fluoranyl)phenyl]-1,3-thiazol-2-amine, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Romero, A.R, Calderone, V, Gentili, M, Lunev, S, Groves, M, Popowicz, G, Domling, A, Sattler, M. | | Deposit date: | 2019-04-01 | | Release date: | 2020-04-15 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A Fragment-Based Approach Identifies an Allosteric Pocket that Impacts Malate Dehydrogenase Activity
Commun Biol, 2021
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1W4M
 | | Structure of the human pleckstrin DEP domain by multidimensional NMR | | Descriptor: | PLECKSTRIN | | Authors: | Civera, C, Simon, B, Stier, G, Sattler, M, Macias, M.J. | | Deposit date: | 2004-07-26 | | Release date: | 2004-12-15 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure and Dynamics of the Human Pleckstrin Dep Domain: Distinct Molecular Features of a Novel Dep Domain Subfamily
Proteins: Struct.,Funct., Genet., 58, 2005
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1VYN
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1D8B
 | | NMR STRUCTURE OF THE HRDC DOMAIN FROM SACCHAROMYCES CEREVISIAE RECQ HELICASE | | Descriptor: | SGS1 RECQ HELICASE | | Authors: | Liu, Z, Macias, M.J, Bottomley, M.J, Stier, G, Linge, J.P, Nilges, M, Bork, P, Sattler, M. | | Deposit date: | 1999-10-21 | | Release date: | 2000-01-10 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins.
Structure Fold.Des., 7, 1999
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4EL6
 | | Crystal structure of IPSE/alpha-1 from Schistosoma mansoni eggs | | Descriptor: | IL-4-inducing protein | | Authors: | Mayerhofer, H, Meyer, H, Tripsianes, K, Barths, D, Blindow, S, Bade, S, Madl, T, Frey, A, Haas, H, Sattler, M, Schramm, G, Mueller-Dieckmann, J. | | Deposit date: | 2012-04-10 | | Release date: | 2013-04-10 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Structure and functional analysis of IPSE/alpha-1, an IL-4-inducing factor secreted from Schistosoma mansoni eggs, reveals an IgE-binding crystallin fold
To be Published
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8POI
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7NDX
 | | Crystal structure of the human HSP40 DNAJB1-CTDs in complex with a peptide of NudC | | Descriptor: | 1,2-ETHANEDIOL, DnaJ homolog subfamily B member 1, Nuclear migration protein nudC | | Authors: | Delhommel, F, Zak, K.M, Popowicz, G.M, Sattler, M. | | Deposit date: | 2021-02-02 | | Release date: | 2022-01-19 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.541 Å) | | Cite: | NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems.
Mol.Cell, 82, 2022
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4QQB
 | | Structural basis for the assembly of the SXL-UNR translation regulatory complex | | Descriptor: | Protein sex-lethal, Upstream of N-ras, isoform A, ... | | Authors: | Hennig, J, Popowicz, G.M, Sattler, M. | | Deposit date: | 2014-06-27 | | Release date: | 2014-09-03 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for the assembly of the Sxl-Unr translation regulatory complex.
Nature, 515, 2014
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8P25
 | | Solution structure of a chimeric U2AF2 RRM2 / FUBP1 N-Box | | Descriptor: | Splicing factor U2AF 65 kDa subunit,Far upstream element-binding protein 1 | | Authors: | Hipp, C, Sattler, M. | | Deposit date: | 2023-05-14 | | Release date: | 2023-07-26 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.
Mol.Cell, 83, 2023
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8Q8J
 | | Crystal structure of human GPX4-R152H | | Descriptor: | Glutathione peroxidase | | Authors: | Napolitano, V, Mourao, A, Kolonko, M, Bostock, M.J, Sattler, M, Conrad, M, Popowicz, G. | | Deposit date: | 2023-08-18 | | Release date: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of human GPX4-R152H
To Be Published
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3DXB
 | | Structure of the UHM domain of Puf60 fused to thioredoxin | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, thioredoxin N-terminally fused to Puf60(UHM) | | Authors: | Corsini, L, Hothorn, M, Scheffzek, K, Stier, G, Sattler, M. | | Deposit date: | 2008-07-24 | | Release date: | 2008-10-28 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Dimerization and Protein Binding Specificity of the U2AF Homology Motif of the Splicing Factor Puf60.
J.Biol.Chem., 284, 2009
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8PXX
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8Q8N
 | | Crystal structure of human GPX4-U46C-I129S-L130S | | Descriptor: | Phospholipid hydroperoxide glutathione peroxidase | | Authors: | Bostock, M.J, Mourao, A, Napolitano, V, Sattler, M, Conrad, M, Popowicz, G. | | Deposit date: | 2023-08-18 | | Release date: | 2024-08-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | An ultra-rare variant of GPX4 reveals the structural basis to avert neurodegeneration
To Be Published
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8PXW
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1FHO
 | | Solution Structure of the PH Domain from the C. Elegans Muscle Protein UNC-89 | | Descriptor: | UNC-89 | | Authors: | Blomberg, N, Baraldi, E, Sattler, M, Saraste, M, Nilges, M. | | Deposit date: | 2000-08-02 | | Release date: | 2000-10-04 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of a PH domain from the C. elegans muscle protein UNC-89 suggests a novel function.
Structure Fold.Des., 8, 2000
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8B8S
 | | Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3 | | Descriptor: | Serine/arginine (SR)-type shuttling mRNA binding protein NPL3 | | Authors: | Kachariya, N, Sattler, M, Keil, P, Strasser, K. | | Deposit date: | 2022-10-04 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR, SOLUTION SCATTERING | | Cite: | Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic Acids Res., 51, 2023
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4QI0
 | | X-ray structure of the ROQ domain from murine Roquin-1 | | Descriptor: | 1,2-ETHANEDIOL, Roquin-1 | | Authors: | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | | Deposit date: | 2014-05-30 | | Release date: | 2014-07-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.
Nat.Struct.Mol.Biol., 21, 2014
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5F5H
 | | X-ray structure of Roquin ROQ domain in complex with Ox40 hexa-loop RNA motif | | Descriptor: | GLYCEROL, RNA (5'-R(P*CP*CP*AP*CP*AP*CP*CP*GP*UP*UP*CP*UP*AP*GP*GP*UP*GP*CP*UP*GP*G)-3'), Roquin-1 | | Authors: | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | | Deposit date: | 2015-12-04 | | Release date: | 2016-04-06 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.
Nat Commun, 7, 2016
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5F5F
 | | X-ray structure of Roquin ROQ domain in complex with a Selex-derived hexa-loop RNA motif | | Descriptor: | RNA (5'-R(P*UP*GP*AP*CP*UP*GP*CP*GP*UP*UP*UP*UP*AP*GP*GP*AP*GP*UP*UP*A)-3'), Roquin-1 | | Authors: | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | | Deposit date: | 2015-12-04 | | Release date: | 2016-04-06 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.
Nat Commun, 7, 2016
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