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PDB: 882 results
7V8E
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BU of 7v8e by Molmil
Crystal structure of IpaH1.4 LRR domain bound to HOIL-1L UBL domain.
Descriptor: RING-type E3 ubiquitin transferase, RanBP-type and C3HC4-type zinc finger-containing protein 1
Authors:Liu, J, Wang, Y, Pan, L.
Deposit date:2021-08-22
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V8F
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BU of 7v8f by Molmil
Crystal structure of UBE2L3 bound to HOIP RING1 domain.
Descriptor: E3 ubiquitin-protein ligase RNF31, Ubiquitin-conjugating enzyme E2 L3, ZINC ION
Authors:Liu, J, Wang, Y, Pan, L.
Deposit date:2021-08-22
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V8H
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BU of 7v8h by Molmil
Crystal structure of LRR domain from Shigella flexneri IpaH1.4
Descriptor: RING-type E3 ubiquitin transferase
Authors:Liu, J, Wang, Y, Pan, L.
Deposit date:2021-08-23
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
4FQG
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BU of 4fqg by Molmil
Crystal structure of the TCERG1 FF4-6 tandem repeat domain
Descriptor: CHLORIDE ION, NICKEL (II) ION, Transcription elongation regulator 1
Authors:Liu, J, Fan, S, Lee, C.J, Greenleaf, A.L, Zhou, P.
Deposit date:2012-06-25
Release date:2013-02-27
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Specific Interaction of the Transcription Elongation Regulator TCERG1 with RNA Polymerase II Requires Simultaneous Phosphorylation at Ser2, Ser5, and Ser7 within the Carboxyl-terminal Domain Repeat.
J.Biol.Chem., 288, 2013
7V59
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BU of 7v59 by Molmil
Cryo-EM structure of spyCas9-sgRNA-DNA dimer
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, DNA (49-MER), RNA (115-MER)
Authors:Liu, J, Deng, P.
Deposit date:2021-08-16
Release date:2022-08-17
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (5.26 Å)
Cite:Nonspecific interactions between SpCas9 and dsDNA sites located downstream of the PAM mediate facilitated diffusion to accelerate target search.
Chem Sci, 12, 2021
4HLR
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BU of 4hlr by Molmil
Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
Descriptor: Gp41, HEXANE-1,6-DIOL
Authors:Liu, J, Lu, M.
Deposit date:2012-10-17
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
To be Published
3U91
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BU of 3u91 by Molmil
Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
Descriptor: Gp41, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500)
Authors:Liu, J, Lu, M.
Deposit date:2011-10-17
Release date:2013-04-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
To be Published
3UIA
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BU of 3uia by Molmil
Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Glycoprotein 41
Authors:Liu, J, Lu, M.
Deposit date:2011-11-04
Release date:2013-05-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Determinants of Trimerization Specificity in HIV-1 gp41 Protein
To be Published
3VBX
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BU of 3vbx by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: 6-bromo-4-hydroxy-2H-chromen-2-one, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
3VC4
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BU of 3vc4 by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: (5Z)-5-[3-(trifluoromethyl)benzylidene]-1,3-thiazolidine-2,4-dione, IMIDAZOLE, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-03
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
3VBT
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BU of 3vbt by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: 4-chloro-2-(1H-pyrazol-3-yl)phenol, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
3VBV
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BU of 3vbv by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: 8-hydroxyquinoline-2-carboxamide, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
3VBQ
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BU of 3vbq by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: (5~{Z})-5-[[3-[6-[(4-azanylcyclohexyl)amino]pyrazin-2-yl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
5WEH
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BU of 5weh by Molmil
Cytochrome c oxidase from Rhodobacter sphaeroides in the reduced state
Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, Aa3-type cytochrome c oxidase subunit IV, CALCIUM ION, ...
Authors:Liu, J, Ferguson-Miller, F, Ling, Q, Hiser, C.
Deposit date:2017-07-10
Release date:2017-09-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Role of conformational change and K-path ligands in controlling cytochrome c oxidase activity.
Biochem. Soc. Trans., 45, 2017
3VBY
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BU of 3vby by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: IMIDAZOLE, Serine/threonine-protein kinase pim-1, furan-2-yl(1H-indol-3-yl)methanone
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
3VBW
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BU of 3vbw by Molmil
Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design
Descriptor: 1,3-dioxo-2,3-dihydro-1H-indene-2-carbonitrile, Serine/threonine-protein kinase pim-1
Authors:Liu, J.
Deposit date:2012-01-02
Release date:2012-03-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.
J.Med.Chem., 55, 2012
5X0W
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BU of 5x0w by Molmil
Molecular mechanism for the binding between Sharpin and HOIP
Descriptor: E3 ubiquitin-protein ligase RNF31, Sharpin
Authors:Liu, J, Li, F, Cheng, X, Pan, L.
Deposit date:2017-01-23
Release date:2017-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights into SHARPIN-Mediated Activation of HOIP for the Linear Ubiquitin Chain Assembly
Cell Rep, 21, 2017
4QLW
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BU of 4qlw by Molmil
Azurin mutant M121E with iron
Descriptor: Azurin, FE (III) ION, NITRATE ION, ...
Authors:Liu, J, Robinson, H, Lu, Y.
Deposit date:2014-06-13
Release date:2014-08-13
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Redesigning the Blue Copper Azurin into a Redox-Active Mononuclear Nonheme Iron Protein: Preparation and Study of Fe(II)-M121E Azurin.
J.Am.Chem.Soc., 136, 2014
4QKT
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BU of 4qkt by Molmil
Azurin mutant M121EM44K with copper
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Azurin, ...
Authors:Liu, J, Robinson, H, Lu, Y.
Deposit date:2014-06-09
Release date:2014-08-13
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (1.641 Å)
Cite:Redesigning the Blue Copper Azurin into a Redox-Active Mononuclear Nonheme Iron Protein: Preparation and Study of Fe(II)-M121E Azurin.
J.Am.Chem.Soc., 136, 2014
7D6H
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BU of 7d6h by Molmil
Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant
Descriptor: PHOSPHATE ION, Papain-like protease, ZINC ION
Authors:Liu, J, Wang, Y, Pan, L.
Deposit date:2020-09-30
Release date:2020-11-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2.
Cell Chem Biol, 28, 2021
7E35
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BU of 7e35 by Molmil
Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant bound to compound S43
Descriptor: N-[(3-acetamidophenyl)methyl]-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide, Non-structural protein 3, ZINC ION
Authors:Liu, J, Wang, Y, Xu, X, Pan, L.
Deposit date:2021-02-08
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2.
Cell Chem Biol, 28, 2021
8XHR
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BU of 8xhr by Molmil
Crystal structure of Mycobacterium tuberculosis MenT3 bound with CTP
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Nucleotidyl transferase AbiEii/AbiGii toxin family protein
Authors:Liu, J, Yashiro, Y, Tomita, K.
Deposit date:2023-12-18
Release date:2024-02-28
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Substrate specificity of Mycobacterium tuberculosis tRNA terminal nucleotidyltransferase toxin MenT3.
Nucleic Acids Res., 52, 2024
7D65
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BU of 7d65 by Molmil
Cryo-EM Structure of human CALHM5 in the presence of Ca2+
Descriptor: 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5
Authors:Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S.
Deposit date:2020-09-29
Release date:2020-12-23
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020
7D61
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BU of 7d61 by Molmil
Cryo-EM Structure of human CALHM5 in the presence of EDTA
Descriptor: 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5
Authors:Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S.
Deposit date:2020-09-28
Release date:2020-12-23
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020
7D60
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BU of 7d60 by Molmil
Cryo-EM Structure of human CALHM5 in the presence of rubidium red
Descriptor: 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, Calcium homeostasis modulator protein 5
Authors:Liu, J, Guan, F.H, Wu, J, Wan, F.T, Lei, M, Ye, S.
Deposit date:2020-09-28
Release date:2020-12-23
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Cryo-EM structures of human calcium homeostasis modulator 5.
Cell Discov, 6, 2020

223532

数据于2024-08-07公开中

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