6U49
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u49 by Molmil](/molmil-images/mine/6u49) | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | 分子名称: | Alpha-hemolysin, SULFATE ION, fos-choline-14 | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | 登録日 | 2019-08-23 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
|
|
1JCD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jcd by Molmil](/molmil-images/mine/1jcd) | Crystal Structure of a Novel Alanine-Zipper Trimer at 1.3 A Resolution, I6A,L9A,V13A,L16A,V20A,L23A,V27A,M30A,V34A,L48A,M51A mutations | 分子名称: | MAJOR OUTER MEMBRANE LIPOPROTEIN | 著者 | Liu, J, Lu, M. | 登録日 | 2001-06-08 | 公開日 | 2003-06-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | An Alanine-Zipper Structure
Determined by Long Range
Intermolecular Interactions J.Biol.Chem., 277, 2002
|
|
1I5Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1i5y by Molmil](/molmil-images/mine/1i5y) | HIV-1 GP41 CORE | 分子名称: | SULFATE ION, TRANSMEMBRANE GLYCOPROTEIN (GP41) | 著者 | Liu, J, Lu, M. | 登録日 | 2001-03-01 | 公開日 | 2002-09-10 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and functional analysis of interhelical interactions in the human
immunodeficiency virus type 1 gp41 envelope glycoprotein by alanine-scanning
mutagenesis. J.Virol., 75, 2001
|
|
1I5X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1i5x by Molmil](/molmil-images/mine/1i5x) | HIV-1 GP41 CORE | 分子名称: | SULFATE ION, TRANSMEMBRANE GLYCOPROTEIN (GP41) | 著者 | Liu, J, Lu, M. | 登録日 | 2001-03-01 | 公開日 | 2002-09-10 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and functional analysis of interhelical interactions in the human
immunodeficiency virus type 1 gp41 envelope glycoprotein by alanine-scanning
mutagenesis. J.Virol., 75, 2001
|
|
6U3F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u3f by Molmil](/molmil-images/mine/6u3f) | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | 分子名称: | Panton-Valentine Leucocidin F, SULFATE ION, fos-choline-14 | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | 登録日 | 2019-08-21 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
|
|
6U2S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u2s by Molmil](/molmil-images/mine/6u2s) | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | 分子名称: | Bi-component leukocidin LukED subunit D, fos-choline-14 | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | 登録日 | 2019-08-20 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
|
|
6U33
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u33 by Molmil](/molmil-images/mine/6u33) | Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus | 分子名称: | Bi-component leukocidin LukED subunit D, NICKEL (II) ION | 著者 | Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M. | 登録日 | 2019-08-21 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence. J.Biol.Chem., 295, 2020
|
|
8F5Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8f5q by Molmil](/molmil-images/mine/8f5q) | Crystal structure of human PCNA in complex with the PIP box of FBH1 | 分子名称: | F-box DNA helicase 1, Proliferating cell nuclear antigen | 著者 | Liu, J, Chaves-Arquero, B, Wei, P, Tencer, H, Zhang, G, Blanco, F, Kutateladze, T. | 登録日 | 2022-11-15 | 公開日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular insight into the PCNA-binding mode of FBH1. Structure, 31, 2023
|
|
1JCC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jcc by Molmil](/molmil-images/mine/1jcc) | Crystal Structure of a Novel Alanine-Zipper Trimer at 1.7 A Resolution, V13A,L16A,V20A,L23A,V27A,M30A,V34A mutations | 分子名称: | MAJOR OUTER MEMBRANE LIPOPROTEIN, ZINC ION | 著者 | Liu, J, Dai, J, Lu, M. | 登録日 | 2001-06-08 | 公開日 | 2003-06-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Zinc-Mediated Helix Capping in A Triple-Helical Protein Biochemistry, 42, 2003
|
|
7SO7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7so7 by Molmil](/molmil-images/mine/7so7) | |
7SO5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7so5 by Molmil](/molmil-images/mine/7so5) | |
1KFN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kfn by Molmil](/molmil-images/mine/1kfn) | |
4EWH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ewh by Molmil](/molmil-images/mine/4ewh) | Co-crystal structure of ACK1 with inhibitor | 分子名称: | 6-{4-[2-(dimethylamino)ethoxy]phenyl}-N-(1,3-dithiolan-2-ylmethyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Activated CDC42 kinase 1 | 著者 | Liu, J, Walker, N, Wang, Z. | 登録日 | 2012-04-27 | 公開日 | 2012-09-19 | 最終更新日 | 2012-10-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Synthesis and optimization of substituted furo[2,3-d]-pyrimidin-4-amines and 7H-pyrrolo[2,3-d]pyrimidin-4-amines as ACK1 inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
|
|
5GP0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gp0 by Molmil](/molmil-images/mine/5gp0) | Crystal structure of geraniol-NUDX1 complex | 分子名称: | GERANYL DIPHOSPHATE, GLYCEROL, Nudix hydrolase 1 | 著者 | Liu, J, Guan, Z, Zou, T, Yin, P. | 登録日 | 2016-07-30 | 公開日 | 2017-10-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | 主引用文献 | Structural Insights into the Substrate Recognition Mechanism of Arabidopsis GPP-Bound NUDX1 for Noncanonical Monoterpene Biosynthesis. Mol Plant, 11, 2018
|
|
1KFM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kfm by Molmil](/molmil-images/mine/1kfm) | |
8EOH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8eoh by Molmil](/molmil-images/mine/8eoh) | crystal structure of human Cytochrome P450 8B1 in complex with a C12-Pyridine Containing Steroid | 分子名称: | 12-(pyridin-3-yl)-8alpha,10alpha,13alpha,14beta-androsta-4,11-diene-3,17-dione, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Liu, J, Scott, E.E. | 登録日 | 2022-10-03 | 公開日 | 2023-08-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Pyridine-containing substrate analogs are restricted from accessing the human cytochrome P450 8B1 active site by tryptophan 281. J.Biol.Chem., 299, 2023
|
|
4MJ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mj5 by Molmil](/molmil-images/mine/4mj5) | Crystal Structure of HLA-A*1101 in complex with H1-22, an influenza A(H1N1) virus epitope | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-11 alpha chain, ... | 著者 | Liu, J, Tan, S, Zhao, M, Qi, J, Gao, G.F. | 登録日 | 2013-09-03 | 公開日 | 2014-10-08 | 最終更新日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Cross-immunity Against Avian Influenza A(H7N9) Virus in the Healthy Population Is Affected by Antigenicity-Dependent Substitutions. J.Infect.Dis., 214, 2016
|
|
4MJ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mj6 by Molmil](/molmil-images/mine/4mj6) | Crystal Structure of HLA-A*1101 in complex with H7-22, an influenza A(H7N9) virus epitope | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-11 alpha chain, ... | 著者 | Liu, J, Tan, S, Zhao, M, Qi, J, Gao, G.F. | 登録日 | 2013-09-03 | 公開日 | 2014-10-08 | 最終更新日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Cross-immunity Against Avian Influenza A(H7N9) Virus in the Healthy Population Is Affected by Antigenicity-Dependent Substitutions. J.Infect.Dis., 214, 2016
|
|
2WR3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wr3 by Molmil](/molmil-images/mine/2wr3) | structure of influenza H2 duck Ontario hemagglutinin with avian receptor | 分子名称: | HEMAGGLUTININ, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. | 登録日 | 2009-08-29 | 公開日 | 2009-09-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
8PE9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8pe9 by Molmil](/molmil-images/mine/8pe9) | Complex between DDR1 DS-like domain and PRTH-101 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Liu, J, Chiang, H, Xiong, W, Laurent, V, Griffiths, S.C, Duelfer, J, Deng, H, Sun, X, Yin, Y.W, Li, W, Audoly, L.P, An, Z, Schuerpf, T, Li, R, Zhang, N. | 登録日 | 2023-06-13 | 公開日 | 2023-06-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.152 Å) | 主引用文献 | A highly selective humanized DDR1 mAb reverses immune exclusion by disrupting collagen fiber alignment in breast cancer. J Immunother Cancer, 11, 2023
|
|
2WRG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wrg by Molmil](/molmil-images/mine/2wrg) | structure of H1 1918 hemagglutinin with human receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, ... | 著者 | Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. | 登録日 | 2009-09-01 | 公開日 | 2009-09-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
2WR0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wr0 by Molmil](/molmil-images/mine/2wr0) | Structures of influenza H2 Hemagglutinins | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, ... | 著者 | Liu, J, Stevens, D, Haire, L, Coombs, P, Russell, R, Gamblin, S, Skehel, J. | 登録日 | 2009-08-28 | 公開日 | 2009-09-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
2WR5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wr5 by Molmil](/molmil-images/mine/2wr5) | structure of influenza H2 duck Ontario hemagglutinin | 分子名称: | HEMAGGLUTININ | 著者 | Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. | 登録日 | 2009-08-29 | 公開日 | 2009-09-29 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
2WRF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wrf by Molmil](/molmil-images/mine/2wrf) | structure of H2 avian jena hemagglutinin with human receptor | 分子名称: | HEMAGGLUTININ, N-acetyl-alpha-neuraminic acid, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose | 著者 | Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. | 登録日 | 2009-09-01 | 公開日 | 2009-09-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
2WR4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2wr4 by Molmil](/molmil-images/mine/2wr4) | structure of influenza H2 duck Ontario hemagglutinin with human receptor | 分子名称: | HEMAGGLUTININ, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Liu, J, Stevens, D.J, Haire, L.F, Walker, P.A, Coombs, P.J, Russell, R.J, Gamblin, S.J, Skehel, J.J. | 登録日 | 2009-08-29 | 公開日 | 2009-09-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | From the Cover: Structures of Receptor Complexes Formed by Hemagglutinins from the Asian Influenza Pandemic of 1957. Proc.Natl.Acad.Sci.USA, 106, 2009
|
|