6C9U
| Crystal structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase in complex with antibody fragment (Fab) | 分子名称: | 6-deoxyerythronolide-B synthase EryA2, modules 3 and 4, Heavy chain of Fab 1B2, ... | 著者 | Deis, L.N, Li, X, Mathews, I.I, Khosla, C. | 登録日 | 2018-01-28 | 公開日 | 2018-05-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module. J. Am. Chem. Soc., 140, 2018
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7XLT
| Cryo-EM Structure of R-loop monoclonal antibody S9.6 in recognizing RNA:DNA hybrids | 分子名称: | DNA, RNA, S9.6 Fab HC, ... | 著者 | Li, Q, Lin, C, Luo, Z, Li, H, Li, X, Sun, Q. | 登録日 | 2022-04-22 | 公開日 | 2022-05-25 | 最終更新日 | 2022-08-03 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Cryo-EM structure of R-loop monoclonal antibody S9.6 in recognizing RNA:DNA hybrids. J Genet Genomics, 49, 2022
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7BW7
| Cryo-EM Structure for the Ectodomain of the Full-length Human Insulin Receptor in Complex with 1 Insulin. | 分子名称: | Insulin fusion, Insulin receptor | 著者 | Yu, D, Zhang, X, Sun, J, Li, X, Wu, Z, Han, X, Fan, C, Ma, Y, Ouyang, Q, Wang, T. | 登録日 | 2020-04-13 | 公開日 | 2021-04-14 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor To Be Published
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7BW8
| Cryo-EM Structure for the Insulin Binding Region in the Ectodomain of the Full-length Human Insulin Receptor in Complex with 1 Insulin | 分子名称: | Insulin fusion, Insulin receptor | 著者 | Yu, D, Zhang, X, Sun, J, Li, X, Wu, Z, Han, X, Fan, C, Ma, Y, Ouyang, Q, Wang, T. | 登録日 | 2020-04-14 | 公開日 | 2021-04-14 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor To Be Published
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7BWA
| Cryo-EM Structure for the Ectodomain of the Full-length Human Insulin Receptor in Complex with 2 Insulin | 分子名称: | Insulin fusion, Insulin receptor | 著者 | Yu, D, Zhang, X, Sun, J, Li, X, Wu, Z, Han, X, Fan, C, Ma, Y, Ouyang, Q, Wang, T. | 登録日 | 2020-04-14 | 公開日 | 2021-04-14 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor To Be Published
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6LQI
| Cryo-EM structure of the mouse Piezo1 isoform Piezo1.1 | 分子名称: | Piezo-type mechanosensitive ion channel component 1 | 著者 | Geng, J, Liu, W, Zhou, H, Zhang, T, Wang, L, Zhang, M, Shen, B, Li, X, Xiao, B. | 登録日 | 2020-01-13 | 公開日 | 2020-03-04 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel. Neuron, 106, 2020
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7F7G
| a linear Peptide Inhibitors in complex with GK domain | 分子名称: | DLG4 GK domain, UNK-ARG-ILE-ARG-ARG-ASP-GLU-TYR-LEU-LYS-ALA-ILE-GLN-UNK | 著者 | Shang, Y, Huang, X, Li, X, Zhang, M. | 登録日 | 2021-06-29 | 公開日 | 2022-02-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.446 Å) | 主引用文献 | Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain. Rsc Chem Biol, 2, 2021
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7XMW
| Crystal structure of anti-CRISPR protein AcrVIA2 | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, AcrVIA2, SELENIUM ATOM, ... | 著者 | Yan, X, Li, X, Song, G. | 登録日 | 2022-04-27 | 公開日 | 2023-05-31 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Structure of AcrVIA2 and its binding mechanism to CRISPR-Cas13a. Biochem.Biophys.Res.Commun., 612, 2022
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7XY9
| Cryo-EM structure of secondary alcohol dehydrogenases TbSADH after carrier-free immobilization based on weak intermolecular interactions | 分子名称: | MAGNESIUM ION, NADP-dependent isopropanol dehydrogenase, ZINC ION | 著者 | Chen, Q, Li, X, Yang, F, Qu, G, Sun, Z.T, Wang, Y.J. | 登録日 | 2022-06-01 | 公開日 | 2023-06-07 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.12 Å) | 主引用文献 | Active and stable alcohol dehydrogenase-assembled hydrogels via synergistic bridging of triazoles and metal ions. Nat Commun, 14, 2023
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7E1Y
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7CLA
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7YPG
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7XEE
| Crystal Structure of the Y53F/N55A mutant of LEH complexed with 2-(3-phenyloxetan-3-yl)ethanamine | 分子名称: | 1,2-ETHANEDIOL, 2-(3-phenyloxetan-3-yl)ethanamine, Limonene-1,2-epoxide hydrolase, ... | 著者 | Qu, G, Li, X, Sun, Z.T. | 登録日 | 2022-03-31 | 公開日 | 2023-01-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.877 Å) | 主引用文献 | Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles. Nat Commun, 13, 2022
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7XEF
| Crystal Structure of the Y53F/N55A mutant of LEH complexed with (R)-(1-benzyl-3-phenylpyrrolidin-3-yl)methanol | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Limonene-1,2-epoxide hydrolase, ... | 著者 | Qu, G, Li, X, Sun, Z.T. | 登録日 | 2022-03-31 | 公開日 | 2023-01-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.816 Å) | 主引用文献 | Rational enzyme design for enabling biocatalytic Baldwin cyclization and asymmetric synthesis of chiral heterocycles. Nat Commun, 13, 2022
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8KGS
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8KGL
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8KGR
| Structure of African swine fever virus topoisomerase II in complex with dsDNA | 分子名称: | DNA (32-MER), DNA (33-MER), DNA topoisomerase 2, ... | 著者 | Cong, J, Xin, U, Li, X, Chen, Y. | 登録日 | 2023-08-19 | 公開日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of African swine fever virus topoisomerase II in complex with dsDNA To Be Published
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8KGQ
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8KGM
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8KGN
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7EXT
| Cryo-EM structure of cyanobacterial phycobilisome from Synechococcus sp. PCC 7002 | 分子名称: | Allophycocyanin alpha subunit, Allophycocyanin beta subunit, Allophycocyanin subunit alpha-B, ... | 著者 | Zheng, L, Zheng, Z, Li, X, Wang, G, Zhang, K, Wei, P, Zhao, J, Gao, N. | 登録日 | 2021-05-28 | 公開日 | 2021-10-06 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural insight into the mechanism of energy transfer in cyanobacterial phycobilisomes. Nat Commun, 12, 2021
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7EYD
| Cryo-EM structure of cyanobacterial phycobilisome from Anabaena sp. PCC 7120 | 分子名称: | Allophycocyanin subunit alpha 1, Allophycocyanin subunit alpha-B, Allophycocyanin subunit beta, ... | 著者 | Zheng, L, Zheng, Z, Li, X, Wang, G, Zhang, K, Wei, P, Zhao, J, Gao, N. | 登録日 | 2021-05-30 | 公開日 | 2021-10-06 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural insight into the mechanism of energy transfer in cyanobacterial phycobilisomes. Nat Commun, 12, 2021
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6JCG
| Room temperature structure of HIV-1 Integrase catalytic core domain by serial femtosecond crystallography. | 分子名称: | CACODYLATE ION, Integrase | 著者 | Park, J.H, Shi, Y, Han, J, Li, X, Kim, T.H, Yun, J.H. | 登録日 | 2019-01-28 | 公開日 | 2019-07-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Non-Cryogenic Structure and Dynamics of HIV-1 Integrase Catalytic Core Domain by X-ray Free-Electron Lasers. Int J Mol Sci, 20, 2019
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7XL5
| Crystal structure of the H42T/A85G/I86A mutant of a nadp-dependent alcohol dehydrogenase | 分子名称: | NADP-dependent isopropanol dehydrogenase | 著者 | Jiang, Y.Y, Qu, G, Li, X, Sun, Z.T, Han, X, Liu, W.D. | 登録日 | 2022-04-21 | 公開日 | 2023-05-31 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (2.604 Å) | 主引用文献 | Engineering the hydrogen transfer pathway of an alcohol dehydrogenase to increase activity by rational enzyme design Mol Catal, 530, 2022
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6LAW
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