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PDB: 440 件
4DVT
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BU of 4dvt by Molmil
Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with AS-II-37
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-(4-chloro-3-fluorophenyl)-N'-[(1S)-1,2,3,4-tetrahydroisoquinolin-1-ylmethyl]ethanediamide, ...
著者Kwon, Y.D, Kwong, P.D.
登録日2012-02-23
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site.
Plos One, 9, 2014
4DVX
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BU of 4dvx by Molmil
Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with MAE-II-188
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-(4-chloro-3-fluorophenyl)-N'-{[(3R)-1-cyclopropylpyrrolidin-3-yl]methyl}ethanediamide, ...
著者Kwon, Y.D, Kwong, P.D.
登録日2012-02-23
公開日2013-02-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site.
Plos One, 9, 2014
4DVS
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BU of 4dvs by Molmil
Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with NBD-557
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-(4-bromophenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)ethanediamide, ...
著者Kwon, Y.D, Kwong, P.D.
登録日2012-02-23
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site.
Plos One, 9, 2014
4DKO
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BU of 4dko by Molmil
Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with TS-II-224
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 gp120 core, ...
著者Kwon, Y.D, LaLonde, J.M, Jones, D.M, Sun, A.W, Courter, J.R, Soeta, T, Kobayashi, T, Princiotto, A.M, Wu, X, Mascola, J, Schon, A, Freire, E, Sodroski, J, Madani, N, Smith III, A.B, Kwong, P.D.
登録日2012-02-03
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.981 Å)
主引用文献Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors.
J.Med.Chem., 55, 2012
5FYJ
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BU of 5fyj by Molmil
Crystal Structure at 3.4 A Resolution of Fully Glycosylated HIV-1 Clade G X1193.c1 SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122, 35O22 and VRC01
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Stewart-Jones, G.B.E, Zhou, T, Thomas, P.V, Kwong, P.D.
登録日2016-03-08
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G
Cell(Cambridge,Mass.), 165, 2016
5F9W
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BU of 5f9w by Molmil
Crystal structure of broadly neutralizing VH1-46 germline-derived CD4-binding site-directed antibody CH235 in complex with HIV-1 clade A/E 93TH057 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of CH235-lineage antibody CH235, Light chain of CH235-lineage antibody CH235, ...
著者Chen, L, Zhou, T, Kwong, P.D.
登録日2015-12-10
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8911 Å)
主引用文献Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.
Cell, 165, 2016
5FYK
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BU of 5fyk by Molmil
Crystal Structure at 3.7 A Resolution of Fully Glycosylated HIV-1 Clade B JR-FL SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122, 35O22 and VRC01
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22, ...
著者Stewart-Jones, G.B.E, Zhou, T, Thomas, P.V, Kwong, P.D.
登録日2016-03-08
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.107 Å)
主引用文献Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G
Cell(Cambridge,Mass.), 165, 2016
4DVW
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BU of 4dvw by Molmil
Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with MAE-II-167
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-(4-chloro-3-fluorophenyl)-N'-[(3aS,6aS)-hexahydrocyclopenta[c]pyrrol-3a(1H)-ylmethyl]ethanediamide, ...
著者Kwon, Y.D, Kwong, P.D.
登録日2012-02-23
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site.
Plos One, 9, 2014
4DKU
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BU of 4dku by Molmil
Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with NBD-09027
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 gp120 core, ...
著者Kwon, Y.D, Debnath, A.K, Kwong, P.D.
登録日2012-02-04
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4902 Å)
主引用文献Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study.
Antimicrob. Agents Chemother., 58, 2014
4DKV
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BU of 4dkv by Molmil
Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with NBD-10007
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 gp120 core, ...
著者Kwon, Y.D, Debnath, A.K, Kwong, P.D.
登録日2012-02-04
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1847 Å)
主引用文献Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study.
Antimicrob. Agents Chemother., 58, 2014
4DVR
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BU of 4dvr by Molmil
Crystal structure of YU2 gp120 core in complex with Fab 48d and NBD-557
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, Fab 48d Heavy chain, ...
著者Kwon, Y.D, Kwong, P.D.
登録日2012-02-23
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site.
Plos One, 9, 2014
4DKQ
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BU of 4dkq by Molmil
Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with DMJ-I-228
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-[(1S,2S)-2-carbamimidamido-2,3-dihydro-1H-inden-1-yl]-N'-(4-chloro-3-fluorophenyl)ethanediamide, ...
著者Kwon, Y.D, LaLonde, J.M, Jones, D.M, Sun, A.W, Courter, J.R, Soeta, T, Kobayashi, T, Princiotto, A.M, Wu, X, Mascola, J, Schon, A, Freire, E, Sodroski, J, Madani, N, Smith III, A.B, Kwong, P.D.
登録日2012-02-03
公開日2012-05-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.888 Å)
主引用文献Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors.
J.Med.Chem., 55, 2012
4DQO
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BU of 4dqo by Molmil
Crystal Structure of PG16 Fab in Complex with V1V2 Region from HIV-1 strain ZM109
分子名称: 1FD6-V1V2 scaffold ZM109 HIV-1 strain, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PG16 Fab Heavy Chain, ...
著者Pancera, M, McLellan, J.S, Kwong, P.D.
登録日2012-02-16
公開日2013-03-06
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.438 Å)
主引用文献Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16.
Nat.Struct.Mol.Biol., 20, 2013
3ONY
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BU of 3ony by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with Fucose
分子名称: 1,2-ETHANEDIOL, Capsid protein, alpha-L-fucopyranose
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-08-30
公開日2011-05-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
3ONU
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BU of 3onu by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026
分子名称: 1,2-ETHANEDIOL, Capsid protein
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-08-30
公開日2011-05-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.395 Å)
主引用文献Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
3PA1
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BU of 3pa1 by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type A
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-10-18
公開日2011-05-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
3LEV
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BU of 3lev by Molmil
HIV-1 antibody 2F5 in complex with epitope scaffold ES2
分子名称: 2F5 ANTIBODY HEAVY CHAIN, 2F5 ANTIBODY LIGHT CHAIN, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Ofek, G, Guenaga, F.J, Schief, W.R, Skinner, J, Baker, D, Wyatt, R, Kwong, P.D.
登録日2010-01-15
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Elicitation of structure-specific antibodies by epitope scaffolds.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LEY
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BU of 3ley by Molmil
2F5 Epitope scaffold elicited anti-HIV-1 monoclonal antibody 6a7 in complex with HIV-1 GP41
分子名称: 6a7 Antibody Heavy Chain, 6a7 Antibody Light Chain, Envelope glycoprotein gp41, ...
著者Ofek, G, Guenaga, F.J, Schief, W.R, Skinner, J, Baker, D, Wyatt, R, Kwong, P.D.
登録日2010-01-15
公開日2010-09-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Elicitation of structure-specific antibodies by epitope scaffolds.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LEX
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BU of 3lex by Molmil
2F5 Epitope scaffold elicited anti-HIV-1 monoclonal antibody 11F10 in complex with HIV-1 GP41
分子名称: 11f10 Antibody Heavy Chain, 11f10 Antibody Light Chain, Envelope glycoprotein gp41
著者Ofek, G, Guenaga, F.J, Schief, W.R, Skinner, J, Baker, D, Wyatt, R, Kwong, P.D.
登録日2010-01-15
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Elicitation of structure-specific antibodies by epitope scaffolds.
Proc.Natl.Acad.Sci.USA, 107, 2010
3Q3A
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BU of 3q3a by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type H2 (triglycan)
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-12-21
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3Q6Q
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BU of 3q6q by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with disordered HBGA type Lea
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2011-01-03
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3QWO
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BU of 3qwo by Molmil
Crystal structure of a motavizumab epitope-scaffold bound to motavizumab Fab
分子名称: 1,2-ETHANEDIOL, SULFATE ION, motavizumab epitope scaffold, ...
著者McLellan, J.S, Kwong, P.D.
登録日2011-02-28
公開日2011-05-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus.
J.Mol.Biol., 409, 2011
3Q38
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BU of 3q38 by Molmil
Crystal structure of P domain from norwalk virus strain vietnam 026 in complex with HBGA type B (triglycan)
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-12-21
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3R6J
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BU of 3r6j by Molmil
Crystal Structure of the Capsid P Domain from Norwalk Virus Strain Hiroshima/1999
分子名称: 1,2-ETHANEDIOL, VP1 protein
著者Hansman, G.S, Biertumpfel, C, McLellan, J.S, Georgiev, I, Chen, L, Zhou, T, Katayama, K, Kwong, P.D.
登録日2011-03-21
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3R0M
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BU of 3r0m by Molmil
Crystal structure of anti-HIV llama VHH antibody A12
分子名称: Llama VHH A12, SULFATE ION
著者Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D.
登録日2011-03-08
公開日2012-03-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Single-Headed Immunoglobulins Efficiently Penetrate CD4-Binding Site and Effectively Neutralize HIV-1
To be Published

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件を2024-07-31に公開中

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