4DKV

Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with NBD-10007

Summary for 4DKV

Entry DOI	10.2210/pdb4dkv/pdb
Related	4DKU
Descriptor	HIV-1 gp120 core, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total)
Functional Keywords	hiv-1 gp120, clade a/e, cd4 mimic, nbd-10007, hydrolase
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	2
Total formula weight	84095.42
Authors	Kwon, Y.D.,Debnath, A.K.,Kwong, P.D. (deposition date: 2012-02-04, release date: 2013-03-20, Last modification date: 2023-09-13)
Primary citation	Curreli, F.,Kwon, Y.D.,Zhang, H.,Yang, Y.,Scacalossi, D.,Kwong, P.D.,Debnath, A.K. Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study. Antimicrob. Agents Chemother., 58:5478-5491, 2014 Cited by PubMed: 25001301 DOI: 10.1128/AAC.03339-14 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1847 Å)

Structure validation