8PVZ
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8RKF
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![BU of 8rkf by Molmil](/molmil-images/mine/8rkf) | Crystal structure of the ZP-N1 and ZP-N2 domains of human ZP2 (hZP2-N1N2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Zona pellucida sperm-binding protein 2 | Authors: | Dioguardi, E, Stsiapanava, A, de Sanctis, D, Jovine, L. | Deposit date: | 2023-12-25 | Release date: | 2024-03-13 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat. Cell, 187, 2024
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4BLB
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![BU of 4blb by Molmil](/molmil-images/mine/4blb) | Crystal structure of a human Suppressor of fused (SUFU)-GLI1p complex | Descriptor: | MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG, ZINC FINGER PROTEIN GLI1, ... | Authors: | Cherry, A.L, Finta, C, Karlstrom, M, De Sanctis, D, Toftgard, R, Jovine, L. | Deposit date: | 2013-05-02 | Release date: | 2013-11-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation Acta Crystallogr.,Sect.D, 69, 2013
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5KOP
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![BU of 5kop by Molmil](/molmil-images/mine/5kop) | Arabidopsis thaliana fucosyltransferase 1 (FUT1) in its apo-form | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Galactoside 2-alpha-L-fucosyltransferase | Authors: | Rocha, J, de Sanctis, D, Breton, C. | Deposit date: | 2016-07-01 | Release date: | 2016-10-12 | Last modified: | 2018-10-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of Arabidopsis thaliana FUT1 Reveals a Variant of the GT-B Class Fold and Provides Insight into Xyloglucan Fucosylation. Plant Cell, 28, 2016
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4BLD
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![BU of 4bld by Molmil](/molmil-images/mine/4bld) | Crystal structure of a human Suppressor of fused (SUFU)-GLI3p complex | Descriptor: | MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG, TRANSCRIPTIONAL ACTIVATOR GLI3, ... | Authors: | Cherry, A.L, Finta, C, Karlstrom, M, De Sanctis, D, Toftgard, R, Jovine, L. | Deposit date: | 2013-05-02 | Release date: | 2013-11-27 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.802 Å) | Cite: | Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation Acta Crystallogr.,Sect.D, 69, 2013
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5II6
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![BU of 5ii6 by Molmil](/molmil-images/mine/5ii6) | Crystal structure of the ZP-N1 domain of mouse sperm receptor ZP2 at 0.95 A resolution | Descriptor: | Zona pellucida sperm-binding protein 2 | Authors: | Dioguardi, E, Han, L, Nishimura, K, De Sanctis, D, Jovine, L. | Deposit date: | 2016-03-01 | Release date: | 2017-06-14 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Structural Basis of Egg Coat-Sperm Recognition at Fertilization. Cell, 169, 2017
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8PW0
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8PVT
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4AWE
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![BU of 4awe by Molmil](/molmil-images/mine/4awe) | The Crystal Structure of Chrysonilia sitophila endo-beta-D-1,4- mannanase | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Goncalves, A.M.D, Silva, C.S, De Sanctis, D, Bento, I. | Deposit date: | 2012-06-01 | Release date: | 2012-10-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Endo-Beta-D-1,4-Mannanase from Chrysonilia Sitophila Displays a Novel Loop Arrangement for Substrate Selectivity Acta Crystallogr.,Sect.D, 68, 2012
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8RKI
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![BU of 8rki by Molmil](/molmil-images/mine/8rki) | Molecular basis of ZP3/ZP1 heteropolymerization: crystal structure of a native vertebrate egg coat filament fragment | Descriptor: | Choriogenin H, YTTERBIUM (III) ION, Zona pellucida sperm-binding protein 3, ... | Authors: | Wiseman, B, Zamora-Caballero, S, de Sanctis, D, Yasumasu, S, Jovine, L. | Deposit date: | 2023-12-25 | Release date: | 2024-03-13 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat. Cell, 187, 2024
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8RKG
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![BU of 8rkg by Molmil](/molmil-images/mine/8rkg) | Crystal structure of tetrameric collagenase-cleaved Xenopus ZP2-N2N3 (cleaved xZP2-N2N3) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BICINE, ... | Authors: | Nishio, S, de Sanctis, D, Jovine, L. | Deposit date: | 2023-12-25 | Release date: | 2024-03-13 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat. Cell, 187, 2024
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4ABX
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![BU of 4abx by Molmil](/molmil-images/mine/4abx) | Crystal structure of Deinococcus radiodurans RecN coiled-coil domain | Descriptor: | DNA REPAIR PROTEIN RECN | Authors: | Pellegrino, S, Radzimanowski, J, de Sanctis, D, McSweeney, S, Timmins, J. | Deposit date: | 2011-12-12 | Release date: | 2012-12-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.041 Å) | Cite: | Structural and Functional Characterization of an Smc-Like Protein Recn: New Insights Into Double-Strand Break Repair. Structure, 20, 2012
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4BAG
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4C14
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![BU of 4c14 by Molmil](/molmil-images/mine/4c14) | The crystal strucuture of PpAzoR in complex with reactive black 5 (RB5) | Descriptor: | DODECAETHYLENE GLYCOL, FMN-DEPENDENT NADH-AZOREDUCTASE 1, [5-[3-[2-[[4-[2-[1-azanyl-7-[2-[4-[methyl-bis(oxidanyl)-$l^{4}-sulfanyl]phenyl]hydrazinyl]-8-oxidanyl-3,6-bis[tris(oxidanyl)-$l^{4}-sulfanyl]naphthalen-2-yl]hydrazinyl]phenyl]-bis(oxidanyl)-$l^{4}-sulfanyl]ethoxy]-7,8-dimethyl-2,4-bis(oxidanylidene)benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentyl] dihydrogen phosphate | Authors: | Goncalves, A.M.D, de Sanctis, D, Bento, I. | Deposit date: | 2013-08-09 | Release date: | 2013-10-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structure of Pseudomonas putida azoreductase - the active site revisited. FEBS J., 280, 2013
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4E05
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![BU of 4e05 by Molmil](/molmil-images/mine/4e05) | Anophelin from the malaria vector inhibits thrombin through a novel reverse-binding mechanism | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Salivary anti-thrombin peptide anophelin, ... | Authors: | Figueiredo, A.C, de Sanctis, D, Gutierrez-Gallego, R, Cereija, T.B, Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B. | Deposit date: | 2012-03-02 | Release date: | 2012-12-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.304 Å) | Cite: | Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector. Proc.Natl.Acad.Sci.USA, 109, 2012
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4E06
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![BU of 4e06 by Molmil](/molmil-images/mine/4e06) | Anophelin from the malaria vector inhibits thrombin through a novel reverse-binding mechanism | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Salivary anti-thrombin peptide anophelin, ... | Authors: | Figueiredo, A.C, de Sanctis, D, Gutierrez-Gallego, R, Cereija, T.B, Macedo-Ribeiro, S, Fuentes-Prior, P, Pereira, P.J.B. | Deposit date: | 2012-03-02 | Release date: | 2012-12-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.196 Å) | Cite: | Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector. Proc.Natl.Acad.Sci.USA, 109, 2012
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4ABY
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![BU of 4aby by Molmil](/molmil-images/mine/4aby) | Crystal structure of Deinococcus radiodurans RecN head domain | Descriptor: | DNA REPAIR PROTEIN RECN | Authors: | Pellegrino, S, Radzimanowski, J, de Sanctis, D, McSweeney, S, Timmins, J. | Deposit date: | 2011-12-12 | Release date: | 2012-12-12 | Last modified: | 2012-12-26 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural and Functional Characterization of an Smc-Like Protein Recn: New Insights Into Double-Strand Break Repair. Structure, 20, 2012
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4BAJ
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![BU of 4baj by Molmil](/molmil-images/mine/4baj) | MYCOBACTERIUM TUBERCULOSIS CHORISMATE SYNTHASE after exposure to 266nm UV laser | Descriptor: | ACETATE ION, CHORISMATE SYNTHASE | Authors: | Pereira, P.J.B, Royant, A, Panjikar, S, de Sanctis, D. | Deposit date: | 2012-09-14 | Release date: | 2013-04-17 | Last modified: | 2019-03-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | In-house UV radiation-damage-induced phasing of selenomethionine-labeled protein structures. J. Struct. Biol., 181, 2013
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4BAI
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![BU of 4bai by Molmil](/molmil-images/mine/4bai) | Mycobacterium tuberculosis Chorismate synthase before exposure to 266 nm UV laser | Descriptor: | ACETATE ION, CHORISMATE SYNTHASE | Authors: | Pereira, P.J.B, Royant, A, Panjikar, S, de Sanctis, D. | Deposit date: | 2012-09-14 | Release date: | 2013-04-17 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | In-house UV radiation-damage-induced phasing of selenomethionine-labeled protein structures. J. Struct. Biol., 181, 2013
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4C0X
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![BU of 4c0x by Molmil](/molmil-images/mine/4c0x) | The crystal strucuture of PpAzoR in complex with anthraquinone-2- sulfonate | Descriptor: | 9,10-dioxo-9,10-dihydroanthracene-2-sulfonic acid, FLAVIN MONONUCLEOTIDE, FMN-DEPENDENT NADH-AZOREDUCTASE 1, ... | Authors: | Goncalves, A.M.D, de Sanctis, D, Bento, I. | Deposit date: | 2013-08-08 | Release date: | 2013-10-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.499 Å) | Cite: | The Crystal Structure of Pseudomonas Putida Azor: The Active Site Revisited. FEBS J., 280, 2013
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4AD8
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![BU of 4ad8 by Molmil](/molmil-images/mine/4ad8) | Crystal structure of a deletion mutant of Deinococcus radiodurans RecN | Descriptor: | DNA REPAIR PROTEIN RECN | Authors: | Pellegrino, S, Radzimanowski, J, de Sanctis, D, McSweeney, S, Timmins, J. | Deposit date: | 2011-12-22 | Release date: | 2012-12-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.998 Å) | Cite: | Structural and Functional Characterization of an Smc-Like Protein Recn: New Insights Into Double-Strand Break Repair. Structure, 20, 2012
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4C0W
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2YFC
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![BU of 2yfc by Molmil](/molmil-images/mine/2yfc) | STRUCTURAL AND FUNCTIONAL INSIGHTS OF DR2231 PROTEIN, THE MAZG-LIKE NUCLEOSIDE TRIPHOSPHATE PYROPHOSPHOHYDROLASE FROM DEINOCOCCUS RADIODURANS, COMPLEXED WITH Mn and dUMP | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Goncalves, A.M.D, De Sanctis, D, Mcsweeney, S.M. | Deposit date: | 2011-04-05 | Release date: | 2011-07-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural and Functional Insights Into Dr2231 Protein, the Mazg-Like Nucleoside Triphosphate Pyrophosphohydrolase from Deinococcus Radiodurans. J.Biol.Chem., 286, 2011
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2YEU
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![BU of 2yeu by Molmil](/molmil-images/mine/2yeu) | Structural and functional insights of DR2231 protein, the MazG-like nucleoside triphosphate pyrophosphohydrolase from Deinococcus radiodurans, complex with Gd | Descriptor: | DR2231, GADOLINIUM ATOM, GLYCEROL, ... | Authors: | Goncalves, A.M.D, de Sanctis, D, McSweeney, S.M. | Deposit date: | 2011-03-30 | Release date: | 2011-07-06 | Last modified: | 2011-09-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Functional Insights Into Dr2231 Protein, the Mazg-Like Nucleoside Triphosphate Pyrophosphohydrolase from Deinococcus Radiodurans. J.Biol.Chem., 286, 2011
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2YFD
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![BU of 2yfd by Molmil](/molmil-images/mine/2yfd) | STRUCTURAL AND FUNCTIONAL INSIGHTS OF DR2231 PROTEIN, THE MAZG-LIKE NUCLEOSIDE TRIPHOSPHATE PYROPHOSPHOHYDROLASE FROM DEINOCOCCUS RADIODURANS, COMPLEXED WITH Mg and dUMP | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, ACETATE ION, CHLORIDE ION, ... | Authors: | Goncalves, A.M.D, De Sanctis, D, Mcsweeney, S.M. | Deposit date: | 2011-04-05 | Release date: | 2011-07-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.767 Å) | Cite: | Structural and Functional Insights Into Dr2231 Protein, the Mazg-Like Nucleoside Triphosphate Pyrophosphohydrolase from Deinococcus Radiodurans. J.Biol.Chem., 286, 2011
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