5CVC
| Structure of maize serine racemase | Descriptor: | MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, Serine racemase | Authors: | Song, Y, Zou, L, Fan, J. | Deposit date: | 2015-07-26 | Release date: | 2016-03-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Crystal structure of maize serine racemase with pyridoxal 5'-phosphate. Acta Crystallogr.,Sect.F, 72, 2016
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8QBF
| Compact state - Pil1 dimer with lipid headgroups fitted in native eisosome lattice bound to plasma membrane microdomain | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, PHOSPHOSERINE, Sphingolipid long chain base-responsive protein PIL1 | Authors: | Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J. | Deposit date: | 2023-08-24 | Release date: | 2024-07-24 | Last modified: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain. Nature, 632, 2024
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8QB7
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8QB8
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8QBB
| Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture +PIP2/-sterol (DOPC, DOPE, DOPS, PI(4,5)P2 50:20:20:10) | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Sphingolipid long chain base-responsive protein PIL1 | Authors: | Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J. | Deposit date: | 2023-08-24 | Release date: | 2024-07-24 | Last modified: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain. Nature, 632, 2024
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8QBD
| Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture +PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol, PI(4,5)P2 35:20:20:15:10) | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, Sphingolipid long chain base-responsive protein PIL1 | Authors: | Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J. | Deposit date: | 2023-08-24 | Release date: | 2024-07-24 | Last modified: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.61 Å) | Cite: | Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain. Nature, 632, 2024
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8QBG
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8QBE
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8QB9
| Helical reconstruction of yeast eisosome protein Pil1 bound to membrane composed of lipid mixture -PIP2/+sterol (DOPC, DOPE, DOPS, cholesterol 30:20:20:30) | Descriptor: | Sphingolipid long chain base-responsive protein PIL1 | Authors: | Kefauver, J.M, Zou, L, Desfosses, A, Loewith, R.J. | Deposit date: | 2023-08-24 | Release date: | 2024-07-24 | Last modified: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain. Nature, 632, 2024
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3N3Z
| Crystal structure of PDE9A (E406A) mutant in complex with IBMX | Descriptor: | 3-ISOBUTYL-1-METHYLXANTHINE, CHLORIDE ION, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, ... | Authors: | Hou, J, Luo, H.-B, Chen, Y, Xu, J, Zhao, R, Zou, L. | Deposit date: | 2010-05-21 | Release date: | 2011-04-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of PDE9A (E406A) mutation in complex with IBMX To be Published
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7XNE
| Crystal structure of CBP bromodomain liganded with Y08284 | Descriptor: | CREB-binding protein, GLYCEROL, N-[3-(1-cyclopropylpyrazol-4-yl)-2-fluoranyl-5-[(1S)-1-oxidanylethyl]phenyl]-3-ethanoyl-7-methoxy-indolizine-1-carboxamide | Authors: | Xiang, Q, Wang, C, Wu, T, Zhang, C, Hu, Q, Luo, G, Hu, J, Zhuang, X, Zou, L, Shen, H, Wu, X, Zhang, Y, Kong, X, Xu, Y. | Deposit date: | 2022-04-28 | Release date: | 2022-07-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer. J.Med.Chem., 65, 2022
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1Z1D
| Structural Model for the interaction between RPA32 C-terminal domain and SV40 T antigen origin binding domain. | Descriptor: | Large T antigen, Replication protein A 32 kDa subunit | Authors: | Arunkumar, A.I, Klimovich, V, Jiang, X, Ott, R.D, Mizoue, L, Fanning, E, Chazin, W.J. | Deposit date: | 2005-03-03 | Release date: | 2005-05-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Insights into hRPA32 C-terminal domain--mediated assembly of the simian virus 40 replisome. Nat.Struct.Mol.Biol., 12, 2005
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3TDM
| Computationally designed TIM-barrel protein, HalfFLR | Descriptor: | Computationally designed two-fold symmetric TIM-barrel protein, FLR (half molecule), PHOSPHATE ION | Authors: | Harp, J.M, Fortenberry, C, Bowman, E, Profitt, W, Dorr, B, Mizoue, L. | Deposit date: | 2011-08-11 | Release date: | 2011-11-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Exploring symmetry as an avenue to the computational design of large protein domains. J.Am.Chem.Soc., 133, 2011
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3TDN
| Computationally designed two-fold symmetric Tim-barrel protein, FLR | Descriptor: | FLR SYMMETRIC ALPHA-BETA TIM BARREL | Authors: | Harp, J.M, Fortenberry, C, Bowman, E, Profitt, W, Dorr, B, Mizoue, L, Meiler, J. | Deposit date: | 2011-08-11 | Release date: | 2011-11-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Exploring symmetry as an avenue to the computational design of large protein domains. J.Am.Chem.Soc., 133, 2011
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