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PDB: 10 results

8UGY
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BU of 8ugy by Molmil
Serotonin 1E receptor (5-HT1eR)-Gi1 Complex bound with Mianserin
Descriptor: 5-hydroxytryptamine receptor 1E, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Zilberg, G, Warren, A.L, Wacker, D.
Deposit date:2023-10-06
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R.
Sci Adv, 10, 2024
8UHB
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BU of 8uhb by Molmil
Cryo-EM Structure of the Ro5256390-bound hTA1-Gs heterotrimer signaling complex
Descriptor: (2R,4S)-4-[(2S)-2-phenylbutyl]-1,3-oxazolidin-2-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zilberg, G, Warren, A.L, Parpounas, A.K, Wacker, D.
Deposit date:2023-10-08
Release date:2024-01-10
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Molecular basis of human trace amine-associated receptor 1 activation.
Nat Commun, 15, 2024
8FYX
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BU of 8fyx by Molmil
Buspirone-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex
Descriptor: Buspirone, CHOLESTEROL HEMISUCCINATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Warren, A.L, Zilberg, G, Capper, M.J, Wacker, D.
Deposit date:2023-01-26
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Structural pharmacology and therapeutic potential of 5-methoxytryptamines.
Nature, 2024
8FY8
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BU of 8fy8 by Molmil
5-MeO-DMT-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex
Descriptor: 2-(5-methoxy-1H-indol-3-yl)-N,N-dimethylethan-1-amine, CHOLESTEROL HEMISUCCINATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Warren, A.L, Zilberg, G, Capper, M.J, Wacker, D.
Deposit date:2023-01-25
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Structural pharmacology and therapeutic potential of 5-methoxytryptamines.
Nature, 2024
8FYL
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BU of 8fyl by Molmil
Vilazodone-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex
Descriptor: 5-{4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide, CHOLESTEROL HEMISUCCINATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Warren, A.L, Zilberg, G, Capper, M.J, Wacker, D.
Deposit date:2023-01-26
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural pharmacology and therapeutic potential of 5-methoxytryptamines.
Nature, 2024
8FYT
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BU of 8fyt by Molmil
LSD-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex
Descriptor: (8alpha)-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carboxamide, CHOLESTEROL HEMISUCCINATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Warren, A.L, Zilberg, G, Capper, M.J, Wacker, D.
Deposit date:2023-01-26
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Structural pharmacology and therapeutic potential of 5-methoxytryptamines.
Nature, 2024
8FYE
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BU of 8fye by Molmil
4-F, 5-MeO-PyrT-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex
Descriptor: 4-fluoro-5-methoxy-3-[2-(pyrrolidin-1-yl)ethyl]-1H-indole, CHOLESTEROL HEMISUCCINATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Warren, A.L, Zilberg, G, Capper, M.J, Wacker, D.
Deposit date:2023-01-26
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural pharmacology and therapeutic potential of 5-methoxytryptamines.
Nature, 2024
8UH3
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BU of 8uh3 by Molmil
Serotonin 1E receptor (5-HT1eR)-Gi1 Complex bound with Setiptiline
Descriptor: 5-hydroxytryptamine receptor 1E, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Wacker, D, Parpounas, A.K, Warren, A.L, Zilberg, G.
Deposit date:2023-10-06
Release date:2024-05-01
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R.
Sci Adv, 10, 2024
8T6U
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BU of 8t6u by Molmil
Cryo-EM structure of human Anion Exchanger 1 bound to Dipyridamole
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Capper, M.J, Zilberg, G, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D.
Deposit date:2023-06-18
Release date:2023-09-13
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Substrate binding and inhibition of the anion exchanger 1 transporter.
Nat.Struct.Mol.Biol., 30, 2023
8T6V
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BU of 8t6v by Molmil
Cryo-EM structure of human Anion Exchanger 1 bound to 4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid (DIDS)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid, ...
Authors:Capper, M.J, Zilberg, G, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D.
Deposit date:2023-06-18
Release date:2023-09-13
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Substrate binding and inhibition of the anion exchanger 1 transporter.
Nat.Struct.Mol.Biol., 30, 2023

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PDB entries from 2024-06-05

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