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PDB: 313 results

5HFL
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BU of 5hfl by Molmil
Gp41-targeting HIV-1 fusion inhibitors with helical Ile-Asp-Leu tail
Descriptor: Envelope glycoprotein,gp41 CHR region
Authors:Zhu, Y, Ye, S, Zhang, R.
Deposit date:2016-01-07
Release date:2017-01-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations
Sci Rep, 6, 2016
4KDR
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BU of 4kdr by Molmil
Crystal Structure of UBIG/SAH complex
Descriptor: 3-demethylubiquinone-9 3-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Zhu, Y, Teng, M, Li, X.
Deposit date:2013-04-25
Release date:2014-04-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Crystal Structure of the UBIG/SAH complex
To be Published
4KDC
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BU of 4kdc by Molmil
Crystal Structure of UBIG
Descriptor: 3-demethylubiquinone-9 3-methyltransferase
Authors:Zhu, Y, Teng, M, Li, X.
Deposit date:2013-04-24
Release date:2014-04-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural and biochemical studies reveal UbiG/Coq3 as a class of novel membrane-binding proteins.
Biochem. J., 470, 2015
4Q77
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BU of 4q77 by Molmil
Crystal structure of Rot, a global regulator of virulence genes in Staphylococcus aureus
Descriptor: GLYCEROL, HTH-type transcriptional regulator rot
Authors:Zhu, Y, Fan, X, Li, X, Teng, M.
Deposit date:2014-04-24
Release date:2014-09-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structure of Rot, a global regulator of virulence genes in Staphylococcus aureus.
Acta Crystallogr.,Sect.D, 70, 2014
4KUC
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BU of 4kuc by Molmil
Crystal structure of ricin-A chain in complex with the antibody 6C2
Descriptor: Ricin, mAb6c2 fab-Heavy chain, mAb6c2 fab-Light chain
Authors:Zhu, Y, Li, X, Teng, M.
Deposit date:2013-05-21
Release date:2013-07-17
Method:X-RAY DIFFRACTION (2.787 Å)
Cite:Structural insights into the neutralization mechanism of mAb 6C2 against ricin
To be Published
6J9M
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BU of 6j9m by Molmil
NmeBH+AcrIIC2
Descriptor: AcrIIC2, CRISPR-associated endonuclease Cas9
Authors:Zhu, Y.L, Gao, A, Serganov, A, Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 74, 2019
6J9K
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BU of 6j9k by Molmil
Apo-AcrIIC2
Descriptor: AcrIIC2, MAGNESIUM ION
Authors:Zhu, Y.L, Gao, A, Serganov, A, Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (2.234 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 74, 2019
6J9L
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BU of 6j9l by Molmil
FnoBH+AcrIIC2
Descriptor: AcrIIC2, HNH endonuclease family protein
Authors:Zhu, Y.L, Gao, A, Serganov, A, Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 74, 2019
6J9N
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BU of 6j9n by Molmil
NmeHNH+AcrIIC3
Descriptor: AcrIIC3, CRISPR-associated endonuclease Cas9
Authors:Zhu, Y.L, Gao, A, Serganov, A, Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (2.606 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 74, 2019
7E9T
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BU of 7e9t by Molmil
Nanometer resolution in situ structure of SARS-CoV-2 post-fusion spike
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2, ...
Authors:Zhu, Y, Tai, L, Zhu, G, Yin, G, Sun, F.
Deposit date:2021-03-05
Release date:2021-11-17
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (10.9 Å)
Cite:Nanometer-resolution in situ structure of the SARS-CoV-2 postfusion spike protein.
Proc.Natl.Acad.Sci.USA, 118, 2021
7XAQ
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BU of 7xaq by Molmil
Cryo-EM structure of PvrA-DNA complex
Descriptor: Probable transcriptional regulator, fadD1
Authors:Zhu, Y.B, Su, Z.M, Bao, R.
Deposit date:2022-03-18
Release date:2023-04-26
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:The Pseudomonas aeruginosa regulator PvrA binds cooperatively to multiple pseudo-palindromic sites to efficiently stimulate target gene
To be published
5VFP
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BU of 5vfp by Molmil
Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ...
Authors:Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y.
Deposit date:2017-04-09
Release date:2018-07-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5VFR
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BU of 5vfr by Molmil
Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ...
Authors:Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y.
Deposit date:2017-04-09
Release date:2018-07-18
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
5VFU
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BU of 5vfu by Molmil
Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y.
Deposit date:2017-04-09
Release date:2018-07-18
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.
Nat Commun, 9, 2018
7C53
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BU of 7c53 by Molmil
Crystal Structure of SARS-CoV-2 HR1 motif in complex with pan-CoVs inhibitor EK1
Descriptor: CALCIUM ION, Spike protein S2',pan-CoVs inhibitor EK1
Authors:Zhu, Y, Yang, X, Sun, F.
Deposit date:2020-05-19
Release date:2021-05-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.278 Å)
Cite:Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation.
Signal Transduct Target Ther, 6, 2021
7WGX
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BU of 7wgx by Molmil
SARS-CoV-2 spike glycoprotein trimer in closed state after treatment with Cathepsin L
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ...
Authors:Zhu, Y, Tai, L, Yin, G, Sun, F.
Deposit date:2021-12-29
Release date:2023-01-04
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies
Cell Discov, 8, 2022
7WGV
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BU of 7wgv by Molmil
SARS-CoV-2 spike glycoprotein trimer in closed state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ...
Authors:Zhu, Y, Tai, L, Yin, G, Sun, F.
Deposit date:2021-12-29
Release date:2023-01-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies
Cell Discov, 8, 2022
7WGY
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BU of 7wgy by Molmil
SARS-CoV-2 spike glycoprotein trimer in Intermediate state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Zhu, Y, Tai, L, Yin, G, Sun, F.
Deposit date:2021-12-29
Release date:2023-01-04
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies
Cell Discov, 8, 2022
7WVX
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BU of 7wvx by Molmil
Cryo-EM structure of the human formyl peptide receptor 2 in complex with fhumanin and Gi2
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-2, ...
Authors:Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-02-11
Release date:2022-04-13
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin.
Nat Commun, 13, 2022
7WVW
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BU of 7wvw by Molmil
Cryo-EM structure of the human formyl peptide receptor 2 in complex with fMYFINILTL and Gi2
Descriptor: FME-TYR-PHE-ILE-ASN-ILE-LEU-THE-LEU, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-02-11
Release date:2022-04-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin.
Nat Commun, 13, 2022
2Q8Y
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BU of 2q8y by Molmil
Structural insight into the enzymatic mechanism of the phophothreonine lyase
Descriptor: 27.5 kDa virulence protein, Mitogen-activated protein kinase 7
Authors:Zhu, Y.-Q, Wang, D.-C, Shao, F.
Deposit date:2007-06-12
Release date:2007-12-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the enzymatic mechanism of the pathogenic MAPK phosphothreonine lyase
Mol.Cell, 28, 2007
7WVY
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BU of 7wvy by Molmil
Cryo-EM structure of the human formyl peptide receptor 2 in complex with Abeta42 and Gi2
Descriptor: Amyloid-beta A4 protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-02-11
Release date:2022-04-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin.
Nat Commun, 13, 2022
7WVV
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BU of 7wvv by Molmil
Cryo-EM structure of the human formyl peptide receptor 2 in complex with fMLFII and Gi2
Descriptor: FME-LEU-PHE-ILE-ILE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-02-11
Release date:2022-04-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin.
Nat Commun, 13, 2022
7WVU
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BU of 7wvu by Molmil
Cryo-EM structure of the human formyl peptide receptor 1 in complex with fMLF and Gi1
Descriptor: FME-LEU-PHE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Zhu, Y, Lin, X, Zong, X, Han, S, Zhao, Q, Wu, B.
Deposit date:2022-02-11
Release date:2022-04-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of FPR2 in recognition of A beta 42 and neuroprotection by humanin.
Nat Commun, 13, 2022
7WGZ
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BU of 7wgz by Molmil
SARS-CoV-2 spike glycoprotein trimer in open state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Zhu, Y, Tai, L, Yin, G, Sun, F.
Deposit date:2021-12-29
Release date:2023-01-04
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies
Cell Discov, 8, 2022

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