7WGV

SARS-CoV-2 spike glycoprotein trimer in closed state

Summary for 7WGV

Entry DOI	10.2210/pdb7wgv/pdb
EMDB information	32490
Descriptor	Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2
Total number of polymer chains	3
Total formula weight	417232.15
Authors	Zhu, Y.,Tai, L.,Yin, G.,Sun, F. (deposition date: 2021-12-29, release date: 2023-01-04, Last modification date: 2024-11-06)
Primary citation	Zhao, M.M.,Zhu, Y.,Zhang, L.,Zhong, G.,Tai, L.,Liu, S.,Yin, G.,Lu, J.,He, Q.,Li, M.J.,Zhao, R.X.,Wang, H.,Huang, W.,Fan, C.,Shuai, L.,Wen, Z.,Wang, C.,He, X.,Chen, Q.,Liu, B.,Xiong, X.,Bu, Z.,Wang, Y.,Sun, F.,Yang, J.K. Novel cleavage sites identified in SARS-CoV-2 spike protein reveal mechanism for cathepsin L-facilitated viral infection and treatment strategies Cell Discov, 8:53-, 2022 Cited by DOI: 10.1038/s41421-022-00419-w PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation