1UKF
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![BU of 1ukf by Molmil](/molmil-images/mine/1ukf) | Crystal Structure of Pseudomonas Avirulence Protein AvrPphB | Descriptor: | Avirulence protein AVRPPH3 | Authors: | Zhu, M, Shao, F, Innes, R.W, Dixon, J.E, Xu, Z. | Deposit date: | 2003-08-21 | Release date: | 2003-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | The crystal structure of Pseudomonas avirulence protein AvrPphB: a papain-like fold with a distinct substrate-binding site. Proc.Natl.Acad.Sci.Usa, 101, 2004
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6JZB
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8GYE
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3HQM
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3HSV
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![BU of 3hsv by Molmil](/molmil-images/mine/3hsv) | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep2 | Descriptor: | Core histone macro-H2A.1, SULFATE ION, Speckle-type POZ protein, ... | Authors: | Zhuang, M, Schulman, B.A, Miller, D. | Deposit date: | 2009-06-10 | Release date: | 2009-10-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. Mol.Cell, 36, 2009
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3HTM
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3HVE
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3HQH
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3HQI
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3HQL
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3HU6
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5CHH
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![BU of 5chh by Molmil](/molmil-images/mine/5chh) | Crystal structure of transcriptional regulator CdpR from Pseudomonas aeruginosa | Descriptor: | AraC family transcriptional regulator | Authors: | Zhao, J.R, Yu, X, Zhu, M, Kang, H.P, Kong, W.N, Ma, J.B, Deng, X, Gan, J.H, Liang, H.H. | Deposit date: | 2015-07-10 | Release date: | 2016-05-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural and Molecular Mechanism of CdpR Involved in Quorum-Sensing and Bacterial Virulence in Pseudomonas aeruginosa Plos Biol., 14, 2016
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5YM9
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8OR1
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![BU of 8or1 by Molmil](/molmil-images/mine/8or1) | Co-crystal strucutre of PD-L1 with low molecular weight inhibitor | Descriptor: | 5-[[5-[[2-chloranyl-3-(2-fluorophenyl)phenyl]methoxy]-2-[(~{E})-2-hydroxyethyliminomethyl]phenoxy]methyl]pyridine-3-carbonitrile, Programmed cell death 1 ligand 1 | Authors: | Zhang, H, Zhou, S, Wu, C, Zhu, M, Yu, Q, Wang, X, Awadasseid, A, Plewka, J, Magiera-Mularz, K, Wu, Y, Zhang, W. | Deposit date: | 2023-04-12 | Release date: | 2023-08-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Design, Synthesis, and Antitumor Activity Evaluation of 2-Arylmethoxy-4-(2,2'-dihalogen-substituted biphenyl-3-ylmethoxy) Benzylamine Derivatives as Potent PD-1/PD-L1 Inhibitors. J.Med.Chem., 66, 2023
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7YDS
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![BU of 7yds by Molmil](/molmil-images/mine/7yds) | The structure of the bispecific antibody targeted PD-L1 and 4-1BB | Descriptor: | Anti-PDL1-VH-CH1, Anti-PDL1-VL-CL, Programmed cell death 1 ligand 1 | Authors: | Gao, Y, Zhu, M, Liu, W.T, Cheng, L.S, Zhu, Z.L, Niu, L.W. | Deposit date: | 2022-07-04 | Release date: | 2023-07-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A bispecific antibody targeted PD-L1 and 4-1BB induces a potent antitumor immune activity in colorectal cancer without systemic toxicity To Be Published
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5J2Y
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![BU of 5j2y by Molmil](/molmil-images/mine/5j2y) | Molecular insight into the regulatory mechanism of the quorum-sensing repressor RsaL in Pseudomonas aeruginosa | Descriptor: | DNA (26-MER), Regulatory protein | Authors: | Zhao, J, Gan, J, Zhang, J, Kang, H, Kong, W, Zhu, M, Li, F, Song, Y, Qin, J, Liang, H. | Deposit date: | 2016-03-30 | Release date: | 2017-04-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of Pseudomonas aeruginosa RsaL bound to promoter DNA reaffirms its role as a global regulator involved in quorum-sensing. Nucleic Acids Res., 45, 2017
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1Y8X
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![BU of 1y8x by Molmil](/molmil-images/mine/1y8x) | Structural basis for recruitment of Ubc12 by an E2-binding domain in NEDD8's E1 | Descriptor: | Ubiquitin-activating enzyme E1C, Ubiquitin-conjugating enzyme E2 M | Authors: | Huang, D.T, Paydar, A, Zhuang, M, Waddell, M.B, Holton, J.M, Schulman, B.A. | Deposit date: | 2004-12-13 | Release date: | 2005-02-08 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1. Mol.Cell, 17, 2005
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2NVU
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![BU of 2nvu by Molmil](/molmil-images/mine/2nvu) | Structure of APPBP1-UBA3~NEDD8-NEDD8-MgATP-Ubc12(C111A), a trapped ubiquitin-like protein activation complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Maltose binding protein/NEDD8-activating enzyme E1 catalytic subunit chimera, ... | Authors: | Huang, D.T, Hunt, H.W, Zhuang, M, Ohi, M.D, Holton, J.M, Schulman, B.A. | Deposit date: | 2006-11-13 | Release date: | 2007-01-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity. Nature, 445, 2007
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