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PDB: 289 件
5EPR
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BU of 5epr by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with SEED11
分子名称: (3~{S})-3-methyl-3,4-dihydro-1~{H}-quinoxalin-2-one, NITRATE ION, Peregrin
著者Zhu, J, Caflisch, A.
登録日2015-11-12
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
J.Med.Chem., 59, 2016
5EQ1
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BU of 5eq1 by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with SEED12
分子名称: 5-METHYL-1,2,4-TRIAZOLO[3,4-B]BENZOTHIAZOLE, NITRATE ION, Peregrin
著者Zhu, J, Caflisch, A.
登録日2015-11-12
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
J.Med.Chem., 59, 2016
5ETB
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BU of 5etb by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with SEED13
分子名称: 1-(7-methyl-1~{H}-indol-3-yl)ethanone, NITRATE ION, Peregrin
著者Zhu, J, Caflisch, A.
登録日2015-11-17
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
J.Med.Chem., 59, 2016
5ETD
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BU of 5etd by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with SEED14
分子名称: 1-(1~{H}-indol-3-yl)ethanone, NITRATE ION, Peregrin
著者Zhu, J, Caflisch, A.
登録日2015-11-17
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
J.Med.Chem., 59, 2016
5EVA
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BU of 5eva by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with SEED16
分子名称: NITRATE ION, Peregrin, ~{N}-[2,4-bis(fluoranyl)phenyl]-2-methyl-pyrazole-3-carboxamide
著者Zhu, J, Caflisch, A.
登録日2015-11-19
公開日2016-06-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
J.Med.Chem., 59, 2016
5EV9
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BU of 5ev9 by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with SEED15
分子名称: NITRATE ION, Peregrin, ~{N}-[5-(1~{H}-pyrazol-4-yl)quinolin-8-yl]ethanamide
著者Zhu, J, Caflisch, A.
登録日2015-11-19
公開日2016-06-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
J.Med.Chem., 59, 2016
5EWW
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BU of 5eww by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with SEED21
分子名称: NITRATE ION, Peregrin, ~{N}-[(2~{R})-butan-2-yl]-1-methyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine
著者Zhu, J, Wiedmer, L, Caflisch, A.
登録日2015-11-21
公開日2016-11-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal structure of the human BRPF1 bromodomain in complex with SEED21
To Be Published
5EWH
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BU of 5ewh by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with SEED19
分子名称: NITRATE ION, Peregrin, isoquinolin-5-ol
著者Zhu, J, Caflisch, A.
登録日2015-11-20
公開日2016-06-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
J.Med.Chem., 59, 2016
5EWC
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BU of 5ewc by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with SEED17
分子名称: NITRATE ION, Peregrin, ethyl (2~{R})-2-methyl-3-oxidanylidene-2,4-dihydro-1~{H}-quinoxaline-6-carboxylate
著者Zhu, J, Caflisch, A.
登録日2015-11-20
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
J.Med.Chem., 59, 2016
5EWV
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BU of 5ewv by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with SEED20
分子名称: 1,5-dimethyl-[1,2,4]triazolo[4,3-a]quinoline, NITRATE ION, Peregrin
著者Zhu, J, Wiedmer, L, Caflisch, A.
登録日2015-11-21
公開日2016-11-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Crystal structure of the human BRPF1 bromodomain in complex with SEED20
To Be Published
4HTX
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BU of 4htx by Molmil
Crystal structure of PDE2 catalytic domain in complex with BAY60-7550
分子名称: 2-(3,4-dimethoxybenzyl)-7-[(2R,3R)-2-hydroxy-6-phenylhexan-3-yl]-5-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one, MAGNESIUM ION, ZINC ION, ...
著者Zhu, J, Huang, Q.
登録日2012-11-02
公開日2013-08-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray Crystal Structure of Phosphodiesterase 2 in Complex with a Highly Selective, Nanomolar Inhibitor Reveals a Binding-Induced Pocket Important for Selectivity.
J.Am.Chem.Soc., 135, 2013
4HTZ
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BU of 4htz by Molmil
Crystal structure of PDE2 catalytic domain in space group P1
分子名称: MAGNESIUM ION, ZINC ION, cGMP-dependent 3',5'-cyclic phosphodiesterase
著者Zhu, J, Huang, Q.
登録日2012-11-02
公開日2013-08-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray Crystal Structure of Phosphodiesterase 2 in Complex with a Highly Selective, Nanomolar Inhibitor Reveals a Binding-Induced Pocket Important for Selectivity.
J.Am.Chem.Soc., 135, 2013
5YPR
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BU of 5ypr by Molmil
Crystal Structure of PSD-95 SH3-GK domain in complex with a synthesized inhibitor
分子名称: Disks large homolog 4, Synthesized GK inhibitor
著者Zhu, J, Zhou, Q, Shang, Y, Weng, Z, Zhu, R, Zhang, M.
登録日2017-11-02
公開日2018-03-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.349 Å)
主引用文献Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs.
Cell Rep, 21, 2017
6BK4
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BU of 6bk4 by Molmil
Crystal structure of the HR-1 domain of Drosophila caprin in the P212121 space group
分子名称: Caprin homolog
著者Zhu, J, Wu, Y, Huang, X, Du, Z.
登録日2017-11-07
公開日2018-11-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a dimerization domain of Drosophila Caprin: further supports the assembly of an evolutionarily conserved ribonucleoprotein complex containing Caprin and FMRP
To Be Published
2QVO
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BU of 2qvo by Molmil
Crystal structure of AF1382 from Archaeoglobus fulgidus
分子名称: Uncharacterized protein AF_1382
著者Zhu, J, Zhao, M, Fu, Z.-Q, Yang, H, Chang, J, Hao, X, Chen, L, Liu, Z.J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2007-08-08
公開日2007-09-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of AF1382 from Archaeoglobus fulgidus.
To be Published
7FBJ
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BU of 7fbj by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing nanobody 17F6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, New antigen receptor variable domain, ...
著者Zhu, J, Xu, T, Feng, B, Liu, J.
登録日2021-07-11
公開日2022-07-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A Class of Shark-Derived Single-Domain Antibodies can Broadly Neutralize SARS-Related Coronaviruses and the Structural Basis of Neutralization and Omicron Escape.
Small Methods, 6, 2022
7FBK
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BU of 7fbk by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain N501Y mutant in complex with neutralizing nanobody 20G6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, New antigen receptor variable domain, Spike protein S1
著者Zhu, J, Xu, T, Feng, B, Liu, J.
登録日2021-07-11
公開日2022-07-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Class of Shark-Derived Single-Domain Antibodies can Broadly Neutralize SARS-Related Coronaviruses and the Structural Basis of Neutralization and Omicron Escape.
Small Methods, 6, 2022
6EKQ
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BU of 6ekq by Molmil
Crystal structure of the human BRPF1 bromodomain complexed with BZ054 in space group C2
分子名称: NITRATE ION, Peregrin, ~{N}-[4-[[(3~{S},5~{R})-3,5-dimethylpiperidin-1-yl]methyl]-1,3-thiazol-2-yl]-2,4-dimethyl-1,3-oxazole-5-carboxamide
著者Zhu, J, Caflisch, A.
登録日2017-09-26
公開日2018-06-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure-based discovery of selective BRPF1 bromodomain inhibitors.
Eur J Med Chem, 155, 2018
6JMT
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BU of 6jmt by Molmil
Crystal structure of GIT/PIX complex
分子名称: ARF GTPase-activating protein GIT2, ZINC ION, beta PIX
著者Zhu, J, Lin, L, Xia, Y, Zhang, R, Zhang, M.
登録日2019-03-13
公開日2020-05-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling.
Mol.Cell, 79, 2020
6JMU
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BU of 6jmu by Molmil
Crystal structure of GIT1/Paxillin complex
分子名称: ARF GTPase-activating protein GIT1, Paxillin
著者Zhu, J, Lin, L, Xia, Y, Zhang, R, Zhang, M.
登録日2019-03-13
公開日2020-05-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling.
Mol.Cell, 79, 2020
7T62
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BU of 7t62 by Molmil
GPC2 HEP CT3 complex
分子名称: CT3, Glypican-2
著者Zhu, J, Cachau, R, De Val Alda, N, Li, N, Ho, M.
登録日2021-12-13
公開日2021-12-22
実験手法ELECTRON MICROSCOPY (21 Å)
主引用文献CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice.
Cell Rep Med, 2, 2021
5YPO
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BU of 5ypo by Molmil
Crystal structure of PSD-95 GK domain in complex with phospho-SAPAP peptide
分子名称: Disks large homolog 4, GLYCEROL, SAPAP
著者Zhu, J, Zhou, Q, Shang, Y, Weng, Z, Zhang, R, Zhang, M.
登録日2017-11-02
公開日2018-03-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs.
Cell Rep, 21, 2017
2P3E
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BU of 2p3e by Molmil
Crystal structure of AQ1208 from Aquifex aeolicus
分子名称: Diaminopimelate decarboxylase
著者Zhu, J, Swindell II, J.T, Chen, L, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Fu, Z.-Q, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-08
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献To be Published
To be Published
2P17
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BU of 2p17 by Molmil
Crystal structure of GK1651 from Geobacillus kaustophilus
分子名称: FE (III) ION, Pirin-like protein
著者Zhu, J, Swindell II, J.T, Chen, L, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Fu, Z.-Q, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-02
公開日2007-05-01
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Crystal structure of GK1651 from Geobacillus kaustophilus
To be Published
7VRU
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BU of 7vru by Molmil
Crystal structure of PacII_M1M2S-DNA-SAH complex
分子名称: DNA (25-mer), S-ADENOSYL-L-HOMOCYSTEINE, Site-specific DNA recognition subunit, ...
著者Zhu, J, Gao, P.
登録日2021-10-25
公開日2022-11-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems.
Nat Commun, 13, 2022

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件を2024-05-29に公開中

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