6JMT
| Crystal structure of GIT/PIX complex | Descriptor: | ARF GTPase-activating protein GIT2, ZINC ION, beta PIX | Authors: | Zhu, J, Lin, L, Xia, Y, Zhang, R, Zhang, M. | Deposit date: | 2019-03-13 | Release date: | 2020-05-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling. Mol.Cell, 79, 2020
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5YPO
| Crystal structure of PSD-95 GK domain in complex with phospho-SAPAP peptide | Descriptor: | Disks large homolog 4, GLYCEROL, SAPAP | Authors: | Zhu, J, Zhou, Q, Shang, Y, Weng, Z, Zhang, R, Zhang, M. | Deposit date: | 2017-11-02 | Release date: | 2018-03-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs. Cell Rep, 21, 2017
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5C89
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5EWW
| Crystal structure of the human BRPF1 bromodomain in complex with SEED21 | Descriptor: | NITRATE ION, Peregrin, ~{N}-[(2~{R})-butan-2-yl]-1-methyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-amine | Authors: | Zhu, J, Wiedmer, L, Caflisch, A. | Deposit date: | 2015-11-21 | Release date: | 2016-11-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Crystal structure of the human BRPF1 bromodomain in complex with SEED21 To Be Published
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5EWV
| Crystal structure of the human BRPF1 bromodomain in complex with SEED20 | Descriptor: | 1,5-dimethyl-[1,2,4]triazolo[4,3-a]quinoline, NITRATE ION, Peregrin | Authors: | Zhu, J, Wiedmer, L, Caflisch, A. | Deposit date: | 2015-11-21 | Release date: | 2016-11-02 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Crystal structure of the human BRPF1 bromodomain in complex with SEED20 To Be Published
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6BK4
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6JMU
| Crystal structure of GIT1/Paxillin complex | Descriptor: | ARF GTPase-activating protein GIT1, Paxillin | Authors: | Zhu, J, Lin, L, Xia, Y, Zhang, R, Zhang, M. | Deposit date: | 2019-03-13 | Release date: | 2020-05-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling. Mol.Cell, 79, 2020
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7VFJ
| Cytochrome c-type biogenesis protein CcmABCD | Descriptor: | Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein B, Heme exporter protein C, ... | Authors: | Zhu, J.P, Zhang, K, Li, J, Zheng, W, Gu, M. | Deposit date: | 2021-09-13 | Release date: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (3.98 Å) | Cite: | Structures of the CcmABCD heme release complex at multiple states. Nat Commun, 13, 2022
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7FBJ
| Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing nanobody 17F6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, New antigen receptor variable domain, ... | Authors: | Zhu, J, Xu, T, Feng, B, Liu, J. | Deposit date: | 2021-07-11 | Release date: | 2022-07-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | A Class of Shark-Derived Single-Domain Antibodies can Broadly Neutralize SARS-Related Coronaviruses and the Structural Basis of Neutralization and Omicron Escape. Small Methods, 6, 2022
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7FBK
| Crystal structure of SARS-CoV-2 receptor binding domain N501Y mutant in complex with neutralizing nanobody 20G6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, New antigen receptor variable domain, Spike protein S1 | Authors: | Zhu, J, Xu, T, Feng, B, Liu, J. | Deposit date: | 2021-07-11 | Release date: | 2022-07-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Class of Shark-Derived Single-Domain Antibodies can Broadly Neutralize SARS-Related Coronaviruses and the Structural Basis of Neutralization and Omicron Escape. Small Methods, 6, 2022
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5VD9
| Crystal structure of human WEE1 kinase domain in complex with RAC-IV-097, a MK1775 analogue | Descriptor: | 1,2-ETHANEDIOL, 1-{6-[(1R)-1-hydroxyethyl]pyridin-2-yl}-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, CHLORIDE ION, ... | Authors: | Zhu, J.-Y, Schonbrunn, E. | Deposit date: | 2017-04-01 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structural basis of Wee family kinase inhibition by small molecules to be published
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5VD4
| CRYSTAL STRUCTURE OF HUMAN WEE1 KINASE DOMAIN IN COMPLEX WITH RAC-IV-016, a MK1775 analougue | Descriptor: | 1,2-ETHANEDIOL, 6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1-{6-[(1S)-2,2,2-trifluoro-1-hydroxyethyl]pyridin-2-yl}-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, CHLORIDE ION, ... | Authors: | Zhu, J.-Y, Schonbrunn, E. | Deposit date: | 2017-04-01 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structural basis of Wee family kinase inhibition by small molecules to be published
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5VD8
| Crystal structure of human WEE1 kinase domain in complex with RAC-IV-099, a MK1775 analogue | Descriptor: | 1,2-ETHANEDIOL, 6-{[3-chloro-4-(4-methylpiperazin-1-yl)phenyl]amino}-1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, CHLORIDE ION, ... | Authors: | Zhu, J.-Y, Schonbrunn, E. | Deposit date: | 2017-04-01 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis of Wee family kinase inhibition by small molecules to be published
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5VD7
| CRYSTAL STRUCTURE OF HUMAN WEE1 KINASE DOMAIN IN COMPLEX WITH RAC-IV-098, a MK1775 analogue | Descriptor: | 1,2-ETHANEDIOL, 6-{[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]amino}-1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, CHLORIDE ION, ... | Authors: | Zhu, J.-Y, Schonbrunn, E. | Deposit date: | 2017-04-01 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural basis of Wee family kinase inhibition by small molecules to be published
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5VD5
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5VDA
| Crystal structure of human WEE1 kinase domain in complex with RAC-IV-101, a MK1775 analogue | Descriptor: | 1,2-ETHANEDIOL, 1-{6-[(1S)-1-hydroxyethyl]pyridin-2-yl}-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, CHLORIDE ION, ... | Authors: | Zhu, J.-Y, Schonbrunn, E. | Deposit date: | 2017-04-01 | Release date: | 2018-04-04 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of Wee family kinase inhibition by small molecules to be published
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7VRU
| Crystal structure of PacII_M1M2S-DNA-SAH complex | Descriptor: | DNA (25-mer), S-ADENOSYL-L-HOMOCYSTEINE, Site-specific DNA recognition subunit, ... | Authors: | Zhu, J, Gao, P. | Deposit date: | 2021-10-25 | Release date: | 2022-11-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems. Nat Commun, 13, 2022
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7VS4
| Crystal structure of PacII_M1M2S-DNA(m6A)-SAH complex | Descriptor: | DNA (25-mer), S-ADENOSYL-L-HOMOCYSTEINE, Site-specific DNA recognition subunit, ... | Authors: | Zhu, J, Gao, P. | Deposit date: | 2021-10-25 | Release date: | 2022-11-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Molecular insights into DNA recognition and methylation by non-canonical type I restriction-modification systems. Nat Commun, 13, 2022
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6QST
| Structure of CREBBP bromodomain with compound 2 bound | Descriptor: | CREB-binding protein, ~{N}-[3-(3-azanyl-5-methyl-1,2-oxazol-4-yl)-5-(5-ethanoyl-2-ethoxy-phenyl)phenyl]furan-2-carboxamide | Authors: | Zhu, J, Sledz, P, Caflisch, A. | Deposit date: | 2019-02-22 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of CREBBP bromodomain with compound 2 bound To Be Published
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2IEL
| CRYSTAL STRUCTURE OF TT0030 from Thermus Thermophilus | Descriptor: | Hypothetical Protein TT0030 | Authors: | Zhu, J, Huang, J, Stepanyuk, G, Chen, L, Chang, J, Zhao, M, Xu, H, Liu, Z.J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2006-09-19 | Release date: | 2006-11-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | CRYSTAL STRUCTURE OF TT0030 from Thermus Thermophilus AT 1.6 ANGSTROMS RESOLUTION To be Published
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2P3E
| Crystal structure of AQ1208 from Aquifex aeolicus | Descriptor: | Diaminopimelate decarboxylase | Authors: | Zhu, J, Swindell II, J.T, Chen, L, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Fu, Z.-Q, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-08 | Release date: | 2007-05-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | To be Published To be Published
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2P17
| Crystal structure of GK1651 from Geobacillus kaustophilus | Descriptor: | FE (III) ION, Pirin-like protein | Authors: | Zhu, J, Swindell II, J.T, Chen, L, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Fu, Z.-Q, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-02 | Release date: | 2007-05-01 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Crystal structure of GK1651 from Geobacillus kaustophilus To be Published
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2KBK
| Solution Structure of BmK-M10 | Descriptor: | Neurotoxin BmK-M10 | Authors: | Zhu, J, Wu, H. | Deposit date: | 2008-11-28 | Release date: | 2009-12-22 | Last modified: | 2019-12-11 | Method: | SOLUTION NMR | Cite: | Solution Structure of BmK-M10 To be Published
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2KBJ
| solution structure of BmKalphaTx11 (minor conformation) | Descriptor: | Toxin Bmka2 | Authors: | Zhu, J, Wu, H. | Deposit date: | 2008-11-28 | Release date: | 2009-12-08 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of BmKalphaTx11, a toxin from the venom of the Chinese scorpion Buthus martensii Karsch Biochem.Biophys.Res.Commun., 391, 2010
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2KBH
| solution structure of BmKalphaTx11 (major conformation) | Descriptor: | Toxin Bmka2 | Authors: | Zhu, J, Wu, H. | Deposit date: | 2008-11-28 | Release date: | 2009-12-08 | Last modified: | 2019-12-11 | Method: | SOLUTION NMR | Cite: | Solution structure of BmKalphaTx11, a toxin from the venom of the Chinese scorpion Buthus martensii Karsch Biochem.Biophys.Res.Commun., 391, 2010
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