6E9C
 
 | | Selenomethionine Derivative Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster | | Descriptor: | Major facilitator family transporter | | Authors: | Zhou, F, Yao, D, Rao, B, Zhang, L, Cao, Y. | | Deposit date: | 2018-07-31 | | Release date: | 2019-08-14 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure of a bacterial homolog to human lysosomal transporter, spinster
Sci Bull (Beijing), 64, 2019
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6EBA
 | | Crystal Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster, in Inward-facing And Unoccupied Conformation | | Descriptor: | Major facilitator family transporter | | Authors: | Zhou, F, Yao, D, Rao, B, Zhang, L, Cao, Y. | | Deposit date: | 2018-08-06 | | Release date: | 2019-08-21 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.812 Å) | | Cite: | Crystal structure of a bacterial homolog to human lysosomal transporter, spinster
Sci Bull (Beijing), 64, 2019
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6E8J
 | | Crystal Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster, in Inward-facing And Occupied Conformation | | Descriptor: | Major facilitator family transporter | | Authors: | Zhou, F, Yao, D, Rao, B, Zhang, L, Cao, Y. | | Deposit date: | 2018-07-30 | | Release date: | 2019-08-14 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3.091 Å) | | Cite: | Crystal structure of a bacterial homolog to human lysosomal transporter, spinster
Sci Bull (Beijing), 64, 2019
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7CZ5
 | | Cryo-EM structure of the human growth hormone-releasing hormone receptor-Gs protein complex | | Descriptor: | CHOLESTEROL, Growth hormone-releasing hormone receptor,growth hormone-releasing hormone receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Zhou, F, Zhang, H, Cong, Z, Zhao, L, Zhou, Q, Mao, C, Cheng, X, Shen, D, Cai, X, Ma, C, Wang, Y, Dai, A, Zhou, Y, Sun, W, Zhao, F, Zhao, S, Jiang, H, Jiang, Y, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | | Deposit date: | 2020-09-07 | | Release date: | 2020-11-18 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structural basis for activation of the growth hormone-releasing hormone receptor.
Nat Commun, 11, 2020
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8XL2
 | | Human acetyl-CoA carboxylase 1 filament in complex with acetyl-CoA (ACC1-inact) | | Descriptor: | ACETYL COENZYME *A, Acetyl-CoA carboxylase 1 | | Authors: | Zhou, F.Y, Zhang, Y.Y, Zhou, Q, Hu, Q. | | Deposit date: | 2023-12-25 | | Release date: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.73 Å) | | Cite: | Filament structures unveil the dynamic organization of human acetyl-CoA carboxylase.
Sci Adv, 10, 2024
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8XL8
 | | Structure of human 3-methylcrotonyl-CoA carboxylase in complex with propionyl-CoA (MCC-PCO) | | Descriptor: | BIOTIN, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... | | Authors: | Zhou, F.Y, Zhang, Y.Y, Zhou, Q, Hu, Q. | | Deposit date: | 2023-12-25 | | Release date: | 2024-10-30 | | Last modified: | 2024-11-27 | | Method: | ELECTRON MICROSCOPY (2.36 Å) | | Cite: | Structural insights into human propionyl-CoA carboxylase (PCC) and 3-methylcrotonyl-CoA carboxylase (MCC)
Elife, 2024
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8XL0
 | | Citrate-induced filament of human acetyl-coenzyme A carboxylase 1 (ACC1-citrate) | | Descriptor: | Acetyl-CoA carboxylase 1, BIOTIN | | Authors: | Zhou, F.Y, Zhang, Y.Y, Zhou, Q, Hu, Q. | | Deposit date: | 2023-12-25 | | Release date: | 2024-10-23 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (4.14 Å) | | Cite: | Filament structures unveil the dynamic organization of human acetyl-CoA carboxylase.
Sci Adv, 10, 2024
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8XL3
 | | Structure of human propionyl-CoA carboxylase at apo-state (PCC-Apo) | | Descriptor: | BIOTIN, Propionyl-CoA carboxylase alpha chain, mitochondrial, ... | | Authors: | Zhou, F.Y, Zhang, Y.Y, Zhou, Q, Hu, Q. | | Deposit date: | 2023-12-25 | | Release date: | 2024-10-30 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Structural insights into human propionyl-CoA carboxylase (PCC) and 3-methylcrotonyl-CoA carboxylase (MCC)
Elife, 2024
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8XL5
 | | Structure of human propionyl-CoA carboxylase in complex with propionyl-CoA (PCC-PCO) | | Descriptor: | BIOTIN, Propionyl-CoA carboxylase alpha chain, mitochondrial, ... | | Authors: | Zhou, F.Y, Zhang, Y.Y, Zhou, Q, Hu, Q. | | Deposit date: | 2023-12-25 | | Release date: | 2024-10-30 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural insights into human propionyl-CoA carboxylase (PCC) and 3-methylcrotonyl-CoA carboxylase (MCC)
Elife, 2024
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8XL6
 | | Structure of human 3-methylcrotonyl-CoA carboxylase at apo-state (MCC-Apo) | | Descriptor: | BIOTIN, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... | | Authors: | Zhou, F.Y, Zhang, Y.Y, Zhou, Q, Hu, Q. | | Deposit date: | 2023-12-25 | | Release date: | 2024-10-30 | | Last modified: | 2024-11-27 | | Method: | ELECTRON MICROSCOPY (2.29 Å) | | Cite: | Structural insights into human propionyl-CoA carboxylase (PCC) and 3-methylcrotonyl-CoA carboxylase (MCC)
Elife, 2024
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8XL4
 | | Structure of human propionyl-CoA carboxylase in complex with acetyl-CoA (PCC-ACO) | | Descriptor: | ACETYL COENZYME *A, BIOTIN, Propionyl-CoA carboxylase alpha chain, ... | | Authors: | Zhou, F.Y, Zhang, Y.Y, Zhou, Q, Hu, Q. | | Deposit date: | 2023-12-25 | | Release date: | 2024-10-30 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | Structural insights into human propionyl-CoA carboxylase (PCC) and 3-methylcrotonyl-CoA carboxylase (MCC)
Elife, 2024
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8XL7
 | | Structure of human 3-methylcrotonyl-CoA carboxylase in complex with acetyl-CoA (MCC-ACO) | | Descriptor: | ACETYL COENZYME *A, BIOTIN, Methylcrotonoyl-CoA carboxylase beta chain, ... | | Authors: | Zhou, F.Y, Zhang, Y.Y, Zhou, Q, Hu, Q. | | Deposit date: | 2023-12-25 | | Release date: | 2024-10-30 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Structural insights into human propionyl-CoA carboxylase (PCC) and 3-methylcrotonyl-CoA carboxylase (MCC)
Elife, 2024
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8XL1
 | | Core region of the human acetyl-CoA carboxylase 1 filament in complex with acetyl-CoA (ACC1-inact) | | Descriptor: | ACETYL COENZYME *A, Acetyl-CoA carboxylase 1 | | Authors: | Zhou, F.Y, Zhang, Y.Y, Zhou, Q, Hu, Q. | | Deposit date: | 2023-12-25 | | Release date: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.57 Å) | | Cite: | Filament structures unveil the dynamic organization of human acetyl-CoA carboxylase.
Sci Adv, 10, 2024
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8X6L
 | | PRMT5:MEP50 WITH SCR-6920 AND SAM | | Descriptor: | 1-ethyl-8-[(2-methoxy-7-azaspiro[3.5]nonan-7-yl)carbonyl]-4-[2-oxidanylidene-2-[(3~{S})-1,2,3,4-tetrahydroisoquinolin-3-yl]ethyl]-2,3-dihydro-1,4-benzodiazepin-5-one, GLYCEROL, Methylosome protein WDR77, ... | | Authors: | Zhou, F, Zhou, F. | | Deposit date: | 2023-11-21 | | Release date: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | PRMT5:MEP50 WITH SCR-6920 AND SAM
To Be Published
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8XKZ
 | | Core region of the citrate-induced human acetyl-CoA carboxylase 1 filament (ACC1-citrate) | | Descriptor: | Acetyl-CoA carboxylase 1, BIOTIN | | Authors: | Zhou, F.Y, Zhang, Y.Y, Zhou, Q, Hu, Q. | | Deposit date: | 2023-12-25 | | Release date: | 2024-10-23 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (2.55 Å) | | Cite: | Filament structures unveil the dynamic organization of human acetyl-CoA carboxylase.
Sci Adv, 10, 2024
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8XL9
 | | Structure of human pyruvate carboxylase | | Descriptor: | BIOTIN, Pyruvate carboxylase, mitochondrial | | Authors: | Zhou, F.Y, Zhang, Y.Y, Zhou, Q, Hu, Q. | | Deposit date: | 2023-12-25 | | Release date: | 2024-11-13 | | Last modified: | 2024-11-27 | | Method: | ELECTRON MICROSCOPY (2.61 Å) | | Cite: | Structural insights into human propionyl-CoA carboxylase (PCC) and 3-methylcrotonyl-CoA carboxylase (MCC).
Elife, 2024
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7DW9
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5Z33
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8XJ2
 | | MAT2A in complex with SAM and allosteric inhibitor SCR-7952 | | Descriptor: | 7-chloranyl-5-(2-cyclopropylpyridin-3-yl)-1-methyl-imidazo[4,5-c]quinolin-4-one, S-ADENOSYLMETHIONINE, S-adenosylmethionine synthase isoform type-2 | | Authors: | Zhou, F. | | Deposit date: | 2023-12-20 | | Release date: | 2024-12-25 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | MAT2A in complex with SAM and allosteric inhibitor SCR-7952
To Be Published
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5KLV
 | | Structure of bos taurus cytochrome bc1 with fenamidone inhibited | | Descriptor: | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3-(phenylamino)-3,5-dihydro-4H-imidazol-4-one, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ... | | Authors: | Xia, D, Esser, L, Zhou, F, Zhou, Y, Xiao, Y, Tang, W.K, Yu, C.A, Qin, Z. | | Deposit date: | 2016-06-25 | | Release date: | 2016-10-12 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.652 Å) | | Cite: | Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
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5KLI
 | | Rhodobacter sphaeroides bc1 with stigmatellin and antimycin | | Descriptor: | (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, (2R,3S,6S,7R,8R)-3-{[3-(FORMYLAMINO)-2-HYDROXYBENZOYL]AMINO}-8-HEXYL-2,6-DIMETHYL-4,9-DIOXO-1,5-DIOXONAN-7-YL (2S)-2-METHYLBUTANOATE, Cytochrome b, ... | | Authors: | Xia, D, Esser, L, Zhou, F, Tang, W.K, Yu, C.A. | | Deposit date: | 2016-06-24 | | Release date: | 2016-10-12 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.996 Å) | | Cite: | Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
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5KKZ
 | | Rhodobacter sphaeroides bc1 with famoxadone | | Descriptor: | (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, ASCORBIC ACID, Cytochrome b, ... | | Authors: | Xia, D, Esser, L, Zhou, F, Tang, W.K, Yu, C.A. | | Deposit date: | 2016-06-23 | | Release date: | 2016-10-12 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.97 Å) | | Cite: | Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
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5KOY
 | | Mouse pgp 34 linker deleted bound with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Multidrug resistance protein 1A | | Authors: | Xia, D, Esser, L, Zhou, F. | | Deposit date: | 2016-07-01 | | Release date: | 2016-12-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.85 Å) | | Cite: | Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
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5KO2
 | | Mouse pgp 34 linker deleted mutant Hg derivative | | Descriptor: | MERCURY (II) ION, Multidrug resistance protein 1A | | Authors: | Xia, D, Esser, L, Zhou, F. | | Deposit date: | 2016-06-29 | | Release date: | 2016-11-30 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
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5KPD
 | | Mouse pgp 34 linker deleted double EQ mutant | | Descriptor: | Multidrug resistance protein 1A | | Authors: | Xia, D, Esser, L, Zhou, F. | | Deposit date: | 2016-07-03 | | Release date: | 2016-11-30 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.35 Å) | | Cite: | Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
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