8XJ2

MAT2A in complex with SAM and allosteric inhibitor SCR-7952

This is a non-PDB format compatible entry.

Summary for 8XJ2

• Entry DOI: 10.2210/pdb8xj2/pdb
• EMDB information: 38392
• Descriptor: S-adenosylmethionine synthase isoform type-2, 7-chloranyl-5-(2-cyclopropylpyridin-3-yl)-1-methyl-imidazo[4,5-c]quinolin-4-one, S-ADENOSYLMETHIONINE (3 entities in total)
• Functional Keywords: methionine adenosyltransferase, cancer, sam, antitumor protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 177082.58

Authors

Zhou, F. (deposition date: 2023-12-20, release date: 2024-12-25)

• Primary citation: Zhou, F.; MAT2A in complex with SAM and allosteric inhibitor SCR-7952; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.16 Å)