8XJ2
MAT2A in complex with SAM and allosteric inhibitor SCR-7952
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | S-adenosylmethionine synthase isoform type-2 | polymer | 395 | 43720.6 | 4 | UniProt (P31153) Pfam (PF00438) Pfam (PF02772) Pfam (PF02773) | Homo sapiens (human) | AdoMet synthase 2,Methionine adenosyltransferase 2,MAT 2,Methionine adenosyltransferase II,MAT-II |
| 2 | E, F, H, J (A, B, C, D) | 7-chloranyl-5-(2-cyclopropylpyridin-3-yl)-1-methyl-imidazo[4,5-c]quinolin-4-one | non-polymer | 350.8 | 4 | Chemie (A1LVL) | |||
| 3 | G, I (B, C) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 174882.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2200.1 | |
| All* | Total formula weight | 177082.6 |
