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PDB: 67 results

6RQM
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BU of 6rqm by Molmil
A blocking anti-CTLA-4 Nanobody (KN044) complexed with CTLA-4
Descriptor: A blocking anti-CTLA-4 nanobody (KN044), Cytotoxic T-lymphocyte protein 4
Authors:Zhang, F, Zhou, A, Gao, H.
Deposit date:2019-05-16
Release date:2020-07-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:A blocking anti-CTLA-4 Nanobody (KN044) complexed with CTLA-4
To Be Published
6RP8
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BU of 6rp8 by Molmil
Crystal Structure of Ipilimumab Fab complexed with CTLA-4 at 2.6A resolution
Descriptor: Antibody Ipilimumab heavy chain, Antibody Ipilimumab light chain, Cytotoxic T-lymphocyte protein 4
Authors:Zhang, F, Zhou, A.
Deposit date:2019-05-14
Release date:2020-07-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Ipilimumab Fab complexed with CTLA-4 at 2.6A resolution
To Be Published
1OC0
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BU of 1oc0 by Molmil
plasminogen activator inhibitor-1 complex with somatomedin B domain of vitronectin
Descriptor: PLASMINOGEN ACTIVATOR INHIBITOR-1, VITRONECTIN
Authors:Read, R.J, Zhou, A, Huntington, J.A, Pannu, N.S, Carrell, R.W.
Deposit date:2003-02-03
Release date:2003-06-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:How Vitronectin Binds Pai-1 to Modulate Fibrinolysis and Cell Migration
Nat.Struct.Biol., 10, 2003
4AJT
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BU of 4ajt by Molmil
The crystal structure of mouse protein-Z dependent protease inhibitor(mZPI)
Descriptor: PROTEIN Z-DEPENDENT PROTEASE INHIBITOR
Authors:Yan, Y, Zhou, A.
Deposit date:2012-02-19
Release date:2012-12-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z.
Blood, 120, 2012
6XY2
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BU of 6xy2 by Molmil
Crystal structure of CTLA-4 complexed with the Fab of HL32 antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytotoxic T-lymphocyte protein 4, Heavy chain, ...
Authors:Gao, H, Zhou, A.
Deposit date:2020-01-29
Release date:2020-12-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure of CTLA-4 complexed with a pH-sensitive cancer immunotherapeutic antibody.
Cell Discov, 6, 2020
5INW
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BU of 5inw by Molmil
Structure of reaction loop cleaved lamprey angiotensinogen
Descriptor: C-terminal peptide of Putative angiotensinogen, Putative angiotensinogen, SULFATE ION
Authors:Wei, H, Zhou, A.
Deposit date:2016-03-08
Release date:2016-10-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism
J.Biol.Chem., 291, 2016
4C41
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BU of 4c41 by Molmil
Corticosteroid-binding globulin with engineered disulphide bridge between residues 100 and 236
Descriptor: CORTICOSTEROID-BINDING GLOBULIN
Authors:Chan, W.L, Zhou, A, Read, R.J.
Deposit date:2013-08-28
Release date:2014-10-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Towards Engineering Hormone-Binding Globulins as Drug Delivery Agents.
Plos One, 9, 2014
4C49
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BU of 4c49 by Molmil
Reactive loop cleaved human CBG in complex with cortisol
Descriptor: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN
Authors:Chan, W.L, Zhou, A, Read, R.J.
Deposit date:2013-09-02
Release date:2014-10-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Role of Sa-Hd Loop Movement in Cortisol Release Mechanism of Cbg
To be Published
5FQL
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BU of 5fql by Molmil
Insights into Hunter syndrome from the structure of iduronate-2- sulfatase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Demydchuk, M, Hill, C.H, Zhou, A, Bunkoczi, G, Stein, P.E, Marchesan, D, Deane, J.E, Read, R.J.
Deposit date:2015-12-11
Release date:2017-01-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insights into Hunter syndrome from the structure of iduronate-2-sulfatase.
Nat Commun, 8, 2017
7WPP
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BU of 7wpp by Molmil
Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 2.85 angstron resolution (1 unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis of von Willebrand factor multimerization and tubular storage.
Blood, 139, 2022
7WQT
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BU of 7wqt by Molmil
Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 4.3 angstron resolution (VWF tube)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-26
Release date:2022-05-25
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of von Willebrand factor multimerization and tubular storage.
Blood, 139, 2022
7WPQ
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BU of 7wpq by Molmil
Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 3.27 angstron resolution (2 units)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (3.267 Å)
Cite:Structural basis of von Willebrand factor multimerization and tubular storage.
Blood, 139, 2022
7WPS
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BU of 7wps by Molmil
Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 4.3 angstron resolution (7 units)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (4.32 Å)
Cite:Structural basis of von Willebrand factor multimerization and tubular storage.
Blood, 139, 2022
7WPR
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BU of 7wpr by Molmil
VWF D'D3 dimer complexed with D1D2 at 4.39 angstron resolution(VWF tube)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (4.39 Å)
Cite:Structural basis of von Willebrand factor multimerization and tubular storage.
Blood, 139, 2022
7WN6
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BU of 7wn6 by Molmil
Cryo-EM structure of VWF D'D3 dimer (R1136M/E1143M mutant) complexed with D1D2 at 3.29 angstron resolution (2 units)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-17
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Structural mechanism of VWF D'D3 dimer formation.
Cell Discov, 8, 2022
7WN4
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BU of 7wn4 by Molmil
Cryo-EM structure of VWF D'D3 dimer (wild type) complexed with D1D2 at 3.4 angstron resolution (1 unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-17
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural mechanism of VWF D'D3 dimer formation.
Cell Discov, 8, 2022
7WN3
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BU of 7wn3 by Molmil
Cryo-EM structure of VWF D'D3 dimer (2M mutant) complexed with D1D2 at 3.29 angstron resolution (2 units)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-17
Release date:2022-05-25
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Structural mechanism of VWF D'D3 dimer formation.
Cell Discov, 8, 2022
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