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PDB: 110 results

5EG7
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BU of 5eg7 by Molmil
The cap binding site of influenza virus protein PB2 as a drug target
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, Polymerase basic protein 2
Authors:Severin, C, Rocha de Moura, T, Liu, Y, Li, K, Zheng, X, Luo, M.
Deposit date:2015-10-26
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The cap-binding site of influenza virus protein PB2 as a drug target.
Acta Crystallogr D Struct Biol, 72, 2016
5EG8
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The cap binding site of influenza virus protein PB2 as a drug target
Descriptor: Polymerase basic protein 2, THIOCYANATE ION
Authors:Liu, Y, Zheng, X, Severin, C, Rocha de Moura, T, Li, K, Luo, M.
Deposit date:2015-10-26
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:The cap-binding site of influenza virus protein PB2 as a drug target.
Acta Crystallogr D Struct Biol, 72, 2016
5WQA
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BU of 5wqa by Molmil
Crystal structure of PDE4D catalytic domain complexed with Selaginpulvilins K
Descriptor: 1-[2-(4-hydroxyphenyl)ethynyl]-9,9-bis(4-methoxyphenyl)-7-oxidanyl-fluorene-2-carbaldehyde, MAGNESIUM ION, ZINC ION, ...
Authors:Huang, Y, Zhang, T, Zheng, X, Yin, S, Luo, H.B.
Deposit date:2016-11-24
Release date:2017-02-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The discovery, complex crystal structure, and recognition mechanism of a novel natural PDE4 inhibitor from Selaginella pulvinata
Biochem. Pharmacol., 130, 2017
5EG9
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BU of 5eg9 by Molmil
The cap binding site of influenza virus protein PB2 as a drug target
Descriptor: Polymerase basic protein 2
Authors:Severin, C, Rocha de Moura, T, Liu, Y, Li, K, Zheng, X, Luo, M.
Deposit date:2015-10-26
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The cap-binding site of influenza virus protein PB2 as a drug target.
Acta Crystallogr D Struct Biol, 72, 2016
5FN0
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BU of 5fn0 by Molmil
Crystal structure of Pseudomonas fluorescens kynurenine-3- monooxygenase (KMO) in complex with GSK180
Descriptor: 3-(5,6-DICHLORO-2-OXOBENZO[D]OXAZOL-3(2H)-YL)PROPANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, KYNURENINE 3-MONOOXYGENASE
Authors:Mole, D.J, Webster, S.P, Uings, I, Zheng, X, Binnie, M, Wilson, K, Hutchinson, J.P, Mirguet, O, Walker, A, Beaufils, B, Ancellin, N, Trottet, L, Beneton, V, Mowat, C.G, Wilkinson, M, Rowland, P, Haslam, C, McBride, A, Homer, N.Z.M, Baily, J.E, Sharp, M.G.F, Garden, O.J, Hughes, J, Howie, S.E.M, Holmes, D, Liddle, J, Iredale, J.P.
Deposit date:2015-11-10
Release date:2016-01-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Kynurenine-3-Monooxygenase Inhibition Prevents Multiple Organ Failure in Rodent Models of Acute Pancreatitis.
Nat.Med. (N.Y.), 22, 2016
2KW0
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BU of 2kw0 by Molmil
Solution structure of N-terminal domain of CcmH from Escherichia.coli
Descriptor: CcmH protein
Authors:Hong, J, Zheng, X, Hu, H, Lin, D.
Deposit date:2010-03-30
Release date:2011-07-13
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Biochemical properties and catalytic domain structure of the CcmH protein from Escherichia coli.
Biochim.Biophys.Acta, 1824, 2012
4ORO
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BU of 4oro by Molmil
Structure of Influenza B PB2 cap-binding domain complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Polymerase PB2
Authors:Liu, Y, Zheng, X.
Deposit date:2014-02-11
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of Influenza B PB2 cap-binding domain complex with GDP
to be published
4OR6
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BU of 4or6 by Molmil
Structure of Influenza B PB2 cap-binding domain with Q325F mutation complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Polymerase basic protein 2
Authors:Liu, Y, Fan, J, Zheng, X.
Deposit date:2014-02-11
Release date:2015-02-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.293 Å)
Cite:The crystal structure of the PB2 cap-binding domain of influenza B virus reveals a novel cap recognition mechanism.
J.Biol.Chem., 290, 2015
4OR4
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BU of 4or4 by Molmil
Structure of Influenza B PB2 cap-binding domain with Q325F mutation complex with m7GDP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Polymerase basic protein 2
Authors:Liu, Y, Fan, J, Zheng, X.
Deposit date:2014-02-10
Release date:2015-02-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:The crystal structure of the PB2 cap-binding domain of influenza B virus reveals a novel cap recognition mechanism.
J.Biol.Chem., 290, 2015
4Q46
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BU of 4q46 by Molmil
The second structure of Influenza B PB2 cap-binding domain complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Polymerase basic protein 2
Authors:Liu, Y, Yang, Y, Zheng, X.
Deposit date:2014-04-13
Release date:2015-02-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of the PB2 cap-binding domain of influenza B virus reveals a novel cap recognition mechanism.
J.Biol.Chem., 290, 2015

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