7T1Y
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![BU of 7t1y by Molmil](/molmil-images/mine/7t1y) | Structure of the Fbw7-Skp1-MycCdegron complex | 分子名称: | F-box/WD repeat-containing protein 7, Myc proto-oncogene protein C terminal degron, S-phase kinase-associated protein 1, ... | 著者 | Wang, B, Rusnac, D.V, Clurman, B.E, Zheng, N. | 登録日 | 2021-12-02 | 公開日 | 2022-02-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor. Sci Adv, 8, 2022
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7T1Z
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![BU of 7t1z by Molmil](/molmil-images/mine/7t1z) | Structure of the Fbw7-Skp1-MycNdegron complex | 分子名称: | F-box/WD repeat-containing protein 7, Myc proto-oncogene N terminal degron, S-phase kinase-associated protein 1, ... | 著者 | Wang, B, Rusnac, D.V, Clurman, B.E, Zheng, N. | 登録日 | 2021-12-02 | 公開日 | 2022-02-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor. Sci Adv, 8, 2022
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6C1P
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![BU of 6c1p by Molmil](/molmil-images/mine/6c1p) | HypoPP mutant | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHAPSO, Ion transport protein, ... | 著者 | Catterall, W.A, Zheng, N, Jiang, D, Gamal El-Din, T.M. | 登録日 | 2018-01-05 | 公開日 | 2018-05-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for gating pore current in periodic paralysis. Nature, 557, 2018
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6BRP
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![BU of 6brp by Molmil](/molmil-images/mine/6brp) | F-box protein form 2 | 分子名称: | F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A | 著者 | Shabek, N, Zheng, N, Mao, H, Hinds, T.R, Ticchiarelli, F, Leyser, O. | 登録日 | 2017-11-30 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structural plasticity of D3-D14 ubiquitin ligase in strigolactone signalling. Nature, 563, 2018
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6BRQ
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![BU of 6brq by Molmil](/molmil-images/mine/6brq) | Crystal structure of rice ASK1-D3 ubiquitin ligase complex crystal form 3 | 分子名称: | F-box/LRR-repeat MAX2 homolog, SKP1-like protein 1A | 著者 | Shabek, N, Zheng, N, Mao, H, Hinds, T.R, Ticchiarelli, F, Leyser, O. | 登録日 | 2017-11-30 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Structural plasticity of D3-D14 ubiquitin ligase in strigolactone signalling. Nature, 563, 2018
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6BRT
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![BU of 6brt by Molmil](/molmil-images/mine/6brt) | F-box protein CTH with hydrolase | 分子名称: | (5R)-5-hydroxy-3-methylfuran-2(5H)-one, D3-CTH-D14-D-ring | 著者 | Shabek, N, Zheng, N, Mao, H, Hinds, T.R, Ticchiarelli, F, Leyser, O. | 登録日 | 2017-12-01 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.393 Å) | 主引用文献 | Structural plasticity of D3-D14 ubiquitin ligase in strigolactone signalling. Nature, 563, 2018
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6BRO
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![BU of 6bro by Molmil](/molmil-images/mine/6bro) | |
4EKW
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![BU of 4ekw by Molmil](/molmil-images/mine/4ekw) | Crystal structure of the NavAb voltage-gated sodium channel (wild-type, 3.2 A) | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, PHOSPHATE ION | 著者 | Payandeh, J, Gamal El-Din, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2012-04-10 | 公開日 | 2012-05-16 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Crystal structure of a voltage-gated sodium channel in two potentially inactivated states. Nature, 486, 2012
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5K1C
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![BU of 5k1c by Molmil](/molmil-images/mine/5k1c) | Crystal structure of the UAF1/WDR20/USP12 complex | 分子名称: | PHOSPHATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Ubiquitin carboxyl-terminal hydrolase 12, ... | 著者 | Li, H, D'Andrea, A.D, Zheng, N. | 登録日 | 2016-05-18 | 公開日 | 2016-07-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20. Mol.Cell, 63, 2016
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5K1B
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![BU of 5k1b by Molmil](/molmil-images/mine/5k1b) | |
5KMD
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![BU of 5kmd by Molmil](/molmil-images/mine/5kmd) | Structure of CavAb in complex with amlodipine | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2016-06-26 | 公開日 | 2016-08-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs. Nature, 537, 2016
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5KLB
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![BU of 5klb by Molmil](/molmil-images/mine/5klb) | Crystal structure of the CavAb voltage-gated calcium channel(wild-type, 2.7A) | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CALCIUM ION, ... | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2016-06-23 | 公開日 | 2016-08-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs. Nature, 537, 2016
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5KLS
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![BU of 5kls by Molmil](/molmil-images/mine/5kls) | Structure of CavAb in complex with Br-dihydropyridine derivative UK-59811 | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2016-06-25 | 公開日 | 2016-08-31 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.299 Å) | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs. Nature, 537, 2016
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5KMH
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![BU of 5kmh by Molmil](/molmil-images/mine/5kmh) | Structure of CavAb in complex with Br-verapamil | 分子名称: | (2~{R})-2-(2-bromophenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-propan-2-yl-pentanenitrile, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, ... | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2016-06-27 | 公開日 | 2016-08-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs. Nature, 537, 2016
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5KMF
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![BU of 5kmf by Molmil](/molmil-images/mine/5kmf) | Structure of CavAb in complex with nimodipine | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2016-06-26 | 公開日 | 2016-08-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs. Nature, 537, 2016
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5KLG
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![BU of 5klg by Molmil](/molmil-images/mine/5klg) | Structure of CavAb(W195Y) in complex with Br-dihydropyridine derivative UK-59811 | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | 登録日 | 2016-06-24 | 公開日 | 2016-08-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs. Nature, 537, 2016
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2P1M
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![BU of 2p1m by Molmil](/molmil-images/mine/2p1m) | TIR1-ASK1 complex structure | 分子名称: | INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, TRANSPORT INHIBITOR RESPONSE 1 protein | 著者 | Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N. | 登録日 | 2007-03-05 | 公開日 | 2007-04-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mechanism of auxin perception by the TIR1 ubiquitin ligase Nature, 446, 2007
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2P1O
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![BU of 2p1o by Molmil](/molmil-images/mine/2p1o) | Mechanism of Auxin Perception by the TIR1 ubiquitin ligase | 分子名称: | Auxin-responsive protein IAA7, INOSITOL HEXAKISPHOSPHATE, NAPHTHALEN-1-YL-ACETIC ACID, ... | 著者 | Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N. | 登録日 | 2007-03-06 | 公開日 | 2007-04-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanism of auxin perception by the TIR1 ubiquitin ligase Nature, 446, 2007
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2P1Q
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![BU of 2p1q by Molmil](/molmil-images/mine/2p1q) | Mechanism of Auxin Perception by the TIR1 ubiquitin ligase | 分子名称: | 1H-INDOL-3-YLACETIC ACID, Auxin-responsive protein IAA7, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N. | 登録日 | 2007-03-06 | 公開日 | 2007-04-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Mechanism of auxin perception by the TIR1 ubiquitin ligase. Nature, 446, 2007
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2P1P
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![BU of 2p1p by Molmil](/molmil-images/mine/2p1p) | Mechanism of Auxin Perception by the TIR1 ubiquitin ligase | 分子名称: | 1H-INDOL-3-YLACETIC ACID, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ... | 著者 | Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N. | 登録日 | 2007-03-06 | 公開日 | 2007-04-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Mechanism of auxin perception by the TIR1 ubiquitin ligase Nature, 446, 2007
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6P6W
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![BU of 6p6w by Molmil](/molmil-images/mine/6p6w) | Cryo-EM structure of voltage-gated sodium channel NavAb N49K/L109A/M116V/G94C/Q150C disulfide crosslinked mutant in the resting state | 分子名称: | Fusion of Maltose-binding protein and voltage-gated sodium channel NavAb | 著者 | Wisedchaisri, G, Tonggu, L, McCord, E, Gamal El-Din, T.M, Wang, L, Zheng, N, Catterall, W.A. | 登録日 | 2019-06-04 | 公開日 | 2019-08-14 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel. Cell, 178, 2019
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6P6Y
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![BU of 6p6y by Molmil](/molmil-images/mine/6p6y) | Crystal structure of voltage-gated sodium channel NavAb V100C/Q150C disulfide crosslinked mutant in the activated state | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein | 著者 | Wisedchaisri, G, Tonggu, L, McCord, E, Gamal El-din, T.M, Wang, L, Zheng, N, Catterall, W.A. | 登録日 | 2019-06-04 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel. Cell, 178, 2019
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6P6X
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![BU of 6p6x by Molmil](/molmil-images/mine/6p6x) | Crystal structure of voltage-gated sodium channel NavAb G94C/Q150C mutant in the activated state | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein | 著者 | Wisedchaisri, G, Tonggu, L, McCord, E, Gamal El-Din, T.M, Wang, L, Zheng, N, Catterall, W.A. | 登録日 | 2019-06-04 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel. Cell, 178, 2019
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3C6N
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![BU of 3c6n by Molmil](/molmil-images/mine/3c6n) | Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling | 分子名称: | (2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ... | 著者 | Tan, X, Zheng, N, Hayashi, K. | 登録日 | 2008-02-04 | 公開日 | 2008-04-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling. Proc.Natl.Acad.Sci.Usa, 105, 2008
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5K19
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![BU of 5k19 by Molmil](/molmil-images/mine/5k19) | |