5KLS

Structure of CavAb in complex with Br-dihydropyridine derivative UK-59811

Summary for 5KLS

Entry DOI	10.2210/pdb5kls/pdb
Descriptor	Ion transport protein, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, ... (5 entities in total)
Functional Keywords	voltage-gated calcium channel, transport protein
Biological source	Arcobacter butzleri (strain RM4018)
Total number of polymer chains	4
Total formula weight	143178.53
Authors	Tang, L.,Gamal EL-Din, T.M.,Swanson, T.M.,Pryde, D.C.,Scheuer, T.,Zheng, N.,Catterall, W.A. (deposition date: 2016-06-25, release date: 2016-08-31, Last modification date: 2024-03-06)
Primary citation	Tang, L.,El-Din, T.M.,Swanson, T.M.,Pryde, D.C.,Scheuer, T.,Zheng, N.,Catterall, W.A. Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs. Nature, 537:117-121, 2016 Cited by PubMed: 27556947 DOI: 10.1038/nature19102 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.299 Å)

Structure validation