8DDR
 
 | | cryo-EM structure of TRPM3 ion channel in the absence of PIP2 | | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ... | | Authors: | Zhao, C, MacKinnon, R. | | Deposit date: | 2022-06-18 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
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8DDV
 | | Cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state4 | | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ... | | Authors: | Zhao, C, MacKinnon, R. | | Deposit date: | 2022-06-19 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
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1V95
 | | Solution Structure of Anticodon Binding Domain from Nuclear Receptor Coactivator 5 (Human KIAA1637 Protein) | | Descriptor: | Nuclear receptor coactivator 5 | | Authors: | Zhao, C, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-01-20 | | Release date: | 2004-07-20 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Anticodon Binding Domain from Nuclear Receptor Coactivator 5 (Human KIAA1637 Protein)
To be Published
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1V5O
 | | Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 1700011N24Rik Protein | | Descriptor: | 1700011N24Rik protein | | Authors: | Zhao, C, Kigawa, T, Tomizawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-11-25 | | Release date: | 2004-05-25 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 1700011N24Rik Protein
To be Published
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1V2Y
 | | Solution Structure of Mouse Hypothetical Gene (RIKEN cDNA 3300001G02) Product Homologous to Ubiquitin Fold | | Descriptor: | 3300001G02Rik protein | | Authors: | Zhao, C, Kigawa, T, Tomizawa, T, Koshiba, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-10-17 | | Release date: | 2004-04-17 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Mouse Hypothetical Gene (RIKEN cDNA 3300001G02) Product Homologous to Ubiquitin Fold
To be Published
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1V6E
 | | Solution Structure of a N-terminal Ubiquitin-like Domain in Mouse Tubulin-specific Chaperone B | | Descriptor: | cytoskeleton-associated protein 1 | | Authors: | Zhao, C, Kigawa, T, Saito, K, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-11-29 | | Release date: | 2004-12-14 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of a N-terminal Ubiquitin-like Domain in Mouse Tubulin-specific Chaperone B
To be Published
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1V5T
 | | Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 8430435I17Rik Protein | | Descriptor: | 8430435I17Rik Protein | | Authors: | Zhao, C, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-11-25 | | Release date: | 2004-05-25 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 8430435I17Rik Protein
To be Published
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1UEQ
 | | Solution Structure of The First PDZ domain of Human Atrophin-1 Interacting Protein 1 (KIAA0705 protein) | | Descriptor: | MEMBRANE ASSOCIATED GUANYLATE KINASE INVERTED-2 (MAGI-2) | | Authors: | Zhao, C, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-05-20 | | Release date: | 2003-11-20 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of The First PDZ domain of Human Atrophin-1 Interacting Protein 1 (KIAA0705 protein)
To be Published
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1UEY
 | | Solution Structure of The First Fibronectin Type III Domain of Human KIAA0343 protein | | Descriptor: | KIAA0343 protein | | Authors: | Zhao, C, Kigawa, T, Muto, Y, Koshiba, S, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-05-22 | | Release date: | 2003-11-22 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of The First Fibronectin Type III Domain of Human KIAA0343 protein
To be Published
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1UG2
 | | Solution Structure of Mouse Hypothetical Gene (2610100B20Rik) Product Homologous to Myb DNA-binding Domain | | Descriptor: | 2610100B20Rik gene product | | Authors: | Zhao, C, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-06-11 | | Release date: | 2004-06-22 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Mouse Hypothetical Gene (2610100B20Rik) Product Homologous to Myb DNA-binding Domain
To be Published
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7S5X
 | | Human KATP channel in open conformation, focused on Kir and one SUR, position 1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Zhao, C, MacKinnon, R. | | Deposit date: | 2021-09-12 | | Release date: | 2021-12-01 | | Last modified: | 2021-12-08 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7S61
 | | Human KATP channel in open conformation, focused on Kir and one SUR, position 5 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Zhao, C, MacKinnon, R. | | Deposit date: | 2021-09-12 | | Release date: | 2021-12-01 | | Last modified: | 2021-12-08 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7S5Y
 | | Human KATP channel in open conformation, focused on Kir and one SUR, position 2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Zhao, C, MacKinnon, R. | | Deposit date: | 2021-09-12 | | Release date: | 2021-12-01 | | Last modified: | 2021-12-08 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7S5Z
 | | Human KATP channel in open conformation, focused on Kir and one SUR, position 3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Zhao, C, MacKinnon, R. | | Deposit date: | 2021-09-12 | | Release date: | 2021-12-01 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7S60
 | | Human KATP channel in open conformation, focused on Kir and one SUR, position 4 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Zhao, C, MacKinnon, R. | | Deposit date: | 2021-09-12 | | Release date: | 2021-12-01 | | Last modified: | 2021-12-08 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Molecular structure of an open human K ATP channel.
Proc.Natl.Acad.Sci.USA, 118, 2021
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8DDW
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8DDX
 | | cryo-EM structure of TRPM3 ion channel in complex with Gbg in the presence of PIP2, tethered by ALFA-nanobody | | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Zhao, C, MacKinnon, R. | | Deposit date: | 2022-06-19 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
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5HHK
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2A4F
 | | Synthesis and Activity of N-Axyl Azacyclic Urea HIV-1 Protease Inhibitors with High Potency Against Multiple Drug Resistant Viral Strains. | | Descriptor: | (5R,6R)-5-BENZYL-6-HYDROXY-2,4-BIS(4-HYDROXY-3-METHOXYBENZYL)-1-[3-(4-HYDROXYPHENYL)PROPANOYL]-1,2,4-TRIAZEPAN-3-ONE, Pol polyprotein | | Authors: | Zhao, C, Sham, H, Sun, M, Lin, S, Stoll, V, Stewart, K.D, Mo, H, Vasavanonda, S, Saldivar, A, McDonald, E. | | Deposit date: | 2005-06-28 | | Release date: | 2005-09-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Synthesis and activity of N-acyl azacyclic urea HIV-1 protease inhibitors with high potency against multiple drug resistant viral strains
Bioorg.Med.Chem.Lett., 15, 2005
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5HHJ
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5IRF
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6K0K
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7V9P
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7V9Q
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7V9O
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